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New Therapy Directly Targets The Cause Of Specific Type Of Amyotrophic Lateral Sclerosis
Date: Apr-05-2013The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis (ALS) - blocking production of a mutant protein that causes an inherited form of the progressive neurodegenerative disease - may be a first step towards a new era in the treatment of such disorders...
Studying Repeat Suicide-Related Behavior In Youth
Date: Apr-05-2013New research out of St. Michael's Hospital has found that multiple factors independently predict what makes youth more likely to make repeat suicide-related behaviour. The study, led by Dr. Anne Rhodes, a research scientist at the hospital's Suicide Studies Research Unit, looked at whether factors such as permanent removal from the parental home by the courts due to maltreatment, neighbourhood size or income, gender, severity of first visit to an emergency department, age or having a mental disorder made youth significantly more likely to repeat suicide-related behavior...
One Specific MicroRNA Appears To Promote Tumor Growth And Cancer Spread
Date: Apr-05-2013Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis. As a therapeutic target, miR-155 could potentially provide a new avenue of treatment when targeted with drugs to suppress its activity. The study was published in a recent online issue of Oncogene...
First Potentially Effective Therapy For Human Prion Disease Identified
Date: Apr-05-2013Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet - incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems. The most well-known of these is Creutzfeldt-Jakob disease, which can be described as the naturally occurring human equivalent of mad cow disease...
3-D Images Created By Imaging Specialists To Aid Surgeons
Date: Apr-05-2013University of Notre Dame researchers have successfully created three-dimensional anatomical models from CT scans using 3-D printing technology, a process that holds promise for medical professionals and their patients. A paper by the researchers, "3D Printing of Preclinical X-ray Computed Tomographic Data Sets," was published in the Journal of Visualized Experiments this week. The strategy was initiated last spring by then-freshman Evan Doney, a Glynn Family Honors student in the laboratory of W. Matthew Leevy, research assistant professor at the Notre Dame Integrated Imaging Facility...
Even High Deductibles Don't Motivate Patients To Shop Around For The Cheapest Medical Services
Date: Apr-05-2013Consumer-directed health plans (CDHPs) offer low premiums but high deductibles on the premise that patients who are faced with deductibles of $1,000 or more for individual coverage (or twice that for family coverage) will shop around for the best price for the health care. In practice, however, that's not the case, according to a new study by the USC Schaeffer Center for Health Policy and Economics and the RAND Corporation...
Much Greater Risk For Urinary Tract Infections In Schizophrenia Relapse
Date: Apr-05-2013Schizophrenia patients experiencing relapse are 29 times more likely than healthy individuals to have a urinary tract infection, researchers report. Urinary tract infections, which can cause painful and frequent urination, are common but patients hospitalized for schizophrenia are even more likely to have a UTI than healthy individuals or even others whose illness is under control, said Dr. Brian J. Miller, psychiatrist and schizophrenia expert at the Medical College of Georgia at Georgia Regents University...
Monkey Model Developed To Study Novel Coronavirus Infection
Date: Apr-05-2013National Institutes of Health (NIH) researchers have developed a model of infection in rhesus macaques that will help scientists around the world better understand how an emerging coronavirus, first identified in September 2012, affects people. The virus has so far infected at least 17 people in the Middle East and Europe, killing 11 of them. The NIH team established the nonhuman primate model in December 2012 and is using it to study how the virus causes disease and to evaluate potential vaccines and antiviral treatments...
Injectable Protein To Reverse Symptoms Of Gynecological Disorders
Date: Apr-05-2013The creation of new blood vessels in the body, called "angiogenesis," is usually discussed in connection with healing wounds and tumors. But it's also an ongoing process in the female reproductive tract, where the growth and breaking of blood vessels is a normal part of the menstrual cycle. But abnormal growth of blood vessels can have painful consequences and resultant pathologies. Now, Prof. Ruth Shalgi and research associate Dr...
Boron Neutron Capture Therapy Could Cure Human Cancers With No Side Effects
Date: Apr-05-2013Cancer painfully ends more than 500,000 lives in the United States each year, according to the Centers for Disease Control and Prevention. The scientific crusade against cancer recently achieved a victory under the leadership of University of Missouri Curators' Professor M. Frederick Hawthorne. Hawthorne's team has developed a new form of radiation therapy that successfully put cancer into remission in mice. This innovative treatment produced none of the harmful side-effects of conventional chemo and radiation cancer therapies...
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