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Imbalance Between An Enzyme Called Neutrophil Elastase And Its Inhibitor Causes Inflammation, Obesity, Insulin Resistance, And Fatty Liver
Date: Apr-04-2013Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease. This enzyme is produced by white blood cells called neutrophils, which play an important role in the body's immune defense against bacteria...
National Survey In The US Finds Problems In Access To Mental Health Care For Children And Teens
Date: Apr-04-2013Every day news reports detail the impact of the deficiencies in the nation's mental health care services. Even more startling, a survey from the University of Michigan reveals that many adults across the U.S. believe children and teens have extremely limited or no access to appropriate mental health care services. The W.K. Kellogg Foundation commissioned the National Voices Project to facilitate a five year study to gauge opportunities available for children and teens at the local level in communities across the U.S...
Using Functional Brain Networks, Epileptic Seizures Can Propagate
Date: Apr-04-2013The seizures that affect people with temporal-lobe epilepsy usually start in a region of the brain called the hippocampus. But they are often able to involve other areas outside the temporal lobe, propagating via anatomically and functionally connected networks in the brain. New research findings that link decreased brain cell concentration to altered functional connectivity in temporal-lobe epilepsy are reported in an article in Brain Connectivity, a bimonthly peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available on the Brain Connectivity website...
Basic Lipid Panel May Miss Millions At Risk Of Heart Disease
Date: Apr-04-2013Study shows LDL cholesterol estimated by basic lipid panel misses nearly 60 percent of at-risk patients with triglycerides over 200 when compared with VAP Lipid Panel The basic lipid panel, relied upon for more than 85 percent of adult cholesterol testing each year, could be leaving millions at risk due to errors in estimation of LDL cholesterol levels...
Many Treatments Offered For The Prevention Of PTSD Lack Sufficient Scientific Evidence
Date: Apr-04-2013Millions of adults are exposed to traumatic events each year. Shortly after exposure many experience symptoms of posttraumatic stress disorder (PTSD) such as flashbacks, emotional numbing and difficulty sleeping. Despite this high rate of exposure, little is known about the effectiveness of treatments aimed at preventing and relieving posttraumatic stress symptoms that adults may experience after such events, according to researchers at the RTI-UNC Evidence-based Practice Center...
How Cells Distinguish Friend From Foe
Date: Apr-04-2013Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by breaking into cells. However, sensing proteins instantly detect the invasion, triggering an alarm that mobilizes the innate immune response. This new understanding of immunity could ultimately help researchers find new targets to treat inflammatory disorders. The paper was published in Nature on March 31...
New Diagnostic Technology May Lead To Individualized Treatments For Prostate Cancer
Date: Apr-04-2013NanoVelcro Chip device captures and isolates potentially high-risk cancer cells A research team jointly led by scientists from Cedars-Sinai Medical Center and the University of California, Los Angeles, have enhanced a device they developed to identify and "grab" circulating tumor cells, or CTCs, that break away from cancers and enter the blood, often leading to the spread of cancer to other parts of the body...
A Breath Of New Life For Children Suffering With Motor Disabilities
Date: Apr-04-2013Breathe Arts Health Research, the social enterprise developing creative approaches to tackle healthcare issues, has designed a new therapy to help young people suffering from hemiplegia. With the help of mentors from Lloyds Banking Group, Breathe is looking to expand its work to benefit children nationally and has signed up British Paralympic athlete, Bethy Woodward as the social enterprise's patron...
Survey Finds College Athletes Twice As Likely As Retired College Athletes To Suffer From Depression
Date: Apr-04-2013A survey of current and former college athletes finds depression levels significantly higher in current athletes, a result that upended the researchers' hypothesis. The finding published in Sports Health suggests the need for more research to understand depression among college athletes...
Landmark Study Shows Loss Of E-Cadherin Drives Prostate Cancer Progression And How To Restart Production
Date: Apr-04-2013Prostate cancer doesn't kill in the prostate - it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. A University of Colorado Cancer Center study published in the Journal of Biological Chemistry describes for the first time a switch that regulates the production of E-Cadherin: the transcription factor SPDEF turns on and off production, leading to metastasis or stopping it cold in models of prostate cancer...
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