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Genetics Journal Highlights For April 2013

Date: Apr-03-2013
Listed below are the selected highlights for the April 2013 issue of the Genetics Society of America's journal, Genetics. The April issue is available online.* ISSUE HIGHLIGHTS Methods, Technology and Resources 1. Marker density and read depth for genotyping populations using genotyping-by-sequencing, pp. 1073-1081 Timothy M. Beissinger, Candice N. Hirsch, Rajandeep S. Sekhon, Jillian M. Foerster, James M. Johnson, German Muttoni, Brieanne Vaillancourt, C. Robin Buell, Shawn M...

How Much We Shrink With Age Influenced By Adult Health Habits

Date: Apr-03-2013
Even if you didn't eat your veggies or drink your milk as a child, your height is still in your hands, reveal new findings by economists from the University of Southern California, Harvard University and Peking University. Using unique data from a new massive longitudinal survey of 17,708 adults beginning at age 45, the researchers show for the first time that lifestyle choices we make in adulthood - and not just the hand we're dealt as children - influence how tall we stand as we age...

Novel Brain Cancer Treatment Uses Genetic Material From Bone Marrow Cells

Date: Apr-03-2013
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of tumor. Specifically, the research team found that introducing genetic material produced by MSCs, significantly reduced a particularly resistant form of malignant brain tumor in living lab rats. "This is the first foray of its type in experimental cancer therapy, and it represents a highly novel and potentially effective treatment," says Michael Chopp, Ph.D...

Disrupting Our Internal Clocks May Lead To A Complete Absence Of 24-Hour Bodily Rhythms And An Immediate Gain In Body Weight

Date: Apr-03-2013
If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published in The FASEB Journal used mice to show that proper sleep patterns are critical for healthy metabolic function, and even mild impairment in our circadian rhythms can lead to serious health consequences, including diabetes and obesity. "We should acknowledge the unforeseen importance of our 24-hour rhythms for health," said Claudia Coomans, Ph.D...

Nonsurgical Option Shows Promise In Restoring Near Vision Without Glasses

Date: Apr-03-2013
By middle age, most people have age-related declines in near vision (presbyopia) requiring bifocals or reading glasses. An emerging technique called hyperopic orthokeratology (OK) may provide a new alternative for restoring near vision without the need for glasses, according to a study, "Refractive Changes from Hyperopic Orthokeratology Monovision in Presbyopes", appearing in the April issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins , a part of Wolters Kluwer Health...

Should Suicidal Patients At Emergency Departments Be Asked About Gun Access?

Date: Apr-03-2013
Although guns are used in over half of all American suicides, a new study shows that many emergency room doctors and nurses do not routinely ask suicidal patients about their access to firearms. "In our study, less than half of emergency room medical providers believe most or all suicides are preventable and many rarely ask about the availability of firearms," said Marian Betz, MD, MPH, at the University of Colorado School of Medicine and lead author of the study. "There is a great opportunity to save lives here that many are not taking advantage of...

Guided Self-Help Found To Be Effective In Treating Childhood Obesity

Date: Apr-03-2013
It is known that family-based treatment that combines nutrition and exercise education, along with behavior modification, is a good approach to help children lose weight. But clinic-based weight-control programs for childhood obesity are not accessible to many families, due to issues such as cost or time commitment. Initial studies at the University of California, San Diego School of Medicine indicate that a self-help treatment program for overweight children and their parents, guided by clinical experts, may be an effective solution...

Fish Oil May Actually Enhance The Function Of B Cells

Date: Apr-03-2013
Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive...

Discovery Of Immunity Protein That Ramps Up Inflammation - And Agents That Can Block It - Offers Potential To Improve Treatments For Pneumonia

Date: Apr-03-2013
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival and improved lung function in animal models of pneumonia. They reported their findings in Nature Immunology. Pneumonia and other infections sometimes provoke an inflammatory response from the body that is more detrimental than the disease-causing bacteria, said senior author Rama Mallampalli, M...

Role Of Cells Other Than Motor Neurons Much Larger Than Anticipated In The Development Of Amyotrophic Lateral Sclerosis

Date: Apr-03-2013
Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a fatal degenerative disease. The discovery holds promise, they say, for identifying new targets for interrupting the disease's progress...