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Patients Benefit From Personalized Therapy Following Development Of New Multiple Myeloma Treatment Guidelines
Date: Apr-02-2013Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy. The guidelines are published in the current issue of the journal Mayo Clinic Proceedings and represent a consensus opinion of hematologists at Mayo Clinic Cancer Center sites in Minnesota, Florida and Arizona...
Scientists Get Inside Look At How AIDS Virus Grooms Its Assault Team
Date: Apr-02-2013A new study by Los Alamos National Laboratory and University of Pennsylvania scientists defines previously unknown properties of transmitted HIV-1, the virus that causes AIDS. The viruses that successfully pass from a chronically infected person to a new individual are both remarkably resistant to a powerful initial human immune-response mechanism, and they are blanketed in a greater amount of envelope protein that helps them access and enter host cells...
New Study Adds Prostate To Cancers Associated With Lynch Syndrome
Date: Apr-02-2013Men with an inherited genetic condition called Lynch syndrome face a higher lifetime risk of developing prostate cancer and appear to develop the disease at an earlier age, according to a new study led by researchers at the University of Michigan Comprehensive Cancer Center. Lynch syndrome is an inherited condition linked to a higher risk of several types of cancer. People with Lynch syndrome have up to 80 percent lifetime risk of colorectal cancer and are also more likely to develop endometrial, gastric, ovarian, urinary tract, pancreatic and brain tumors...
Targeting Early-Morning Smoking May Reduce Risk For Lung And Oral Cancers
Date: Apr-02-2013The sooner a person smokes a cigarette upon waking in the morning, the more likely he or she is to acquire lung or oral cancer, according to Penn State researchers. "We found that smokers who consume cigarettes immediately after waking have higher levels of NNAL -- a metabolite of the tobacco-specific carcinogen NNK -- in their blood than smokers who refrain from smoking a half hour or more after waking, regardless of how many cigarettes they smoke per day," said Steven Branstetter, assistant professor of biobehavioral health...
Researchers Find Gene For Common Form Of Epilepsy
Date: Apr-02-2013Researchers have found a gene linked to the most common form of epilepsy that could one day lead to a genetic test for the condition. They suggest the discovery will also give new insights into other neurological conditions such as autism. Lead researcher, Ingrid Scheffer, professor and pediatric neurologist, of the Florey Neuroscience Institute in Melbourne, Victoria, Australia, and an international team of colleagues, write about their discovery of the focal epilepsy gene in the 31 March online issue of Nature Genetics...
ALS Disease Involves Cells Other Than Motor Neurons
Date: Apr-02-2013A new study of mice finds that cells other than motor neurons play a bigger role in the development of the fatal degenerative disease amyotrophic lateral sclerosis (ALS) than first thought. It shows that the cells that produce the myelin insulation that protects nerve cells may play a key role. If confirmed, this would suggest ALS has more in common with multiple scleroris (MS) than previously thought...
Gene Evolution Accelerated By Head-On Collisions Between DNA-Code Reading Machineries
Date: Apr-02-2013Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, as University of Washington scientists explain in the journal Nature...
Early Pancreatic Cancer Detection May Be Possible With New Metabolite-Based Diagnostic Test
Date: Apr-02-2013A new diagnostic test that uses a scientific technique known as metabolomic analysis may be a safe and easy screening method that could improve the prognosis of patients with pancreatic cancer through earlier detection. Researchers examined the utility of metabolomic analysis as a diagnostic method for pancreatic cancer and then validated the new approach, according to study results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research...
The Effects Of Combined Hormone Therapy On Breast Cancer Risk
Date: Apr-02-2013Dr. Rowan Chlebowski, MD, PhD, Los Angeles Biomedical Research Institute lead researcher and author of a study released by the Journal of the National Cancer Institute, issued the following statement regarding the latest findings from the Women's Health Initiative, the largest-ever study of hormonal therapy in post-menopausal women. The study Dr. Chlebowski authored reported that estrogen plus progestin use is linked with increased breast cancer incidence...
Prototype Helmet Could Mean Firefighters Are Not Left In The Dark
Date: Apr-02-2013A specially-adapted 'tactile helmet', developed by researchers at the University of Sheffield, could provide fire-fighters operating in challenging conditions with vital clues about their surroundings. The helmet is fitted with a number of ultrasound sensors that are used to detect the distances between the helmet and nearby walls or other obstacles. These signals are transmitted to vibration pads that are attached to the inside of the helmet, touching the wearer's forehead...
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