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High-Fat Foods May Be A Factor In Glucose Control

Date: Apr-02-2013
In a study of patients with type 1 diabetes, Joslin researchers found that dietary fat can affect glucose levels and insulin requirements. These findings, which appeared in the April edition of Diabetes Care, have major implications for the management of type 1 diabetes. Research has shown that dietary fat and free fatty acids (FFAs) impair insulin sensitivity and increase glucose production. Most studies have focused on the role of fat in the development of type 2 diabetes...

Potential New Treatments For Hormone-Therapy-Related Breast Cancers

Date: Apr-02-2013
More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause. New research by University of Missouri scientist Salman Hyder may lead to treatments for breast cancers associated with taking these synthetic hormones. Hyder, along with an international team, found that hormone-therapy-related breast cancer cells have a physical feature that could be attacked by cancer therapies...

Discovery Has Implications For Improving The Treatment Of Neuropathic Pain

Date: Apr-02-2013
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury. The discovery has implications for improving the treatment of neuropathic pain, a complex and largely mysterious form of chronic pain that afflicts over 100 million Americans. The findings are published in the Journal of Neuroscience...

Cognitive Development May Be Affected By Marital Conflict

Date: Apr-02-2013
Marital conflict is a significant source of environmental stress for children, and witnessing such conflict may harm children's stress response systems which, in turn, may affect their mental and intellectual development. These conclusions come from a new study by researchers at Auburn University and the Catholic University of America. The study appears in the journal Child Development. Researchers looked at 251 children from a variety of backgrounds who lived in two-parent homes...

Pre-Kindergarten Program Boosts Children's Skills In Boston Public Schools

Date: Apr-02-2013
Boston Public Schools' prekindergarten program is substantially improving children's readiness to start kindergarten, according to a new study of more than 2,000 children enrolled there. The program uses research-based curricula and coaching of teachers, is taught primarily by masters-level teachers, and is open to any child regardless of family income. The study, out of Harvard University, appears in the journal Child Development. Some of the study's findings on the effects of the program are the largest found to date in evaluations of large-scale public prekindergarten programs...

Impoverished Children Harmed By Multiple Moves

Date: Apr-02-2013
Poor children who move three or more times before they turn 5 have more behavior problems than their peers, according to a new study by researchers at Cornell University and the National Employment Law Project. The study is published in the journal Child Development. Moving is a fairly common experience for American families; in 2002, 6.5 percent of all children had been living in their current home for less than six months. Among low-income children, that number rose to 10 percent...

Vitamin D Supplements May Help Maintain Kidney Function In Transplant Recipients

Date: Apr-02-2013
Vitamin D deficiency may decrease kidney function in transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The finding suggests that vitamin D supplementation may help improve the health of kidney transplant recipients. Vitamin D deficiency is prevalent in patients with kidney failure. It's not clear how this affects patients after they receive a kidney transplant...

Examining Dialysis Survival Among Racial And Ethnic Subgroups Could Improve Care For All Patients With Kidney Disease

Date: Apr-02-2013
Among kidney failure patients on dialysis, Hispanics tend to live the longest and Whites the shortest, with Blacks' survival time in between these two, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). Examining the reasons for these survival differences could help improve care for all patients with kidney disease. While Blacks have a shorter average lifespan than Whites in the general US population, some studies indicate that among kidney failure patients on dialysis, Blacks tend to live longer than whites...

Designer Antibodies For HIV

Date: Apr-02-2013
An effective vaccine against HIV-1 remains elusive, but one promising strategy focuses on designer antibodies that have much broader potency than most normal, exquisitely specific antibodies. These broadly neutralizing antibodies (bNAbs) can handle the high mutation rate of HIV particles that makes normal, very specific antibodies useless within a short space of time. A study published by Cell Press in the journal Cell reveals surprising mutations in these antibodies that are crucial for strong protection against HIV-1. The findings could guide efforts to design better HIV-1 vaccines...

Just 'Weight' Until Menopause: How Estrogen Deficiency Affects Women's Fat Absorption

Date: Apr-02-2013
Women tend to carry excess fat in their hips and thighs, while men tend to carry it on their stomachs. But after menopause, things start to change: many women's fat storage patterns start to resemble those of men. This indicates that there's a link between estrogen and body fat storage. This connection is well documented, but the underlying mechanisms remained poorly understood until now...