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Climate Change Driving Diarrheal Disease
Date: Mar-28-2013In a National Science Foundation funded study, Kathleen Alexander, an associate professor of wildlife at Virginia Tech, found that climate drives a large part of diarrheal disease and increases the threat of climate change for vulnerable communities. The only study of its kind in Sub-Saharan Africa is based on three decades of historical data and has important implications for arid countries around the world struggling with poverty and increasing health challenges...
Depression Can Rob Us Of The Full Benefits Of Healthy Behaviors
Date: Mar-28-2013Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine. The finding - based on measurements of the cardio-metabolic risk marker C-reactive protein (CRP) - points to another potential danger of depression, which afflicts an estimated one in 10 adults in the United States. Study results were published online in the journal Brain, Behavior, and Immunity...
Genomic, Molecular Findings Help To Customize Personalized Medicine For Pediatric Brain Tumors
Date: Mar-28-2013Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child's tumor...
Increased Risk Of Adverse Neonatal And Maternal Outcomes In Overweight And Obese Women
Date: Mar-28-2013Overweight and obese women are more likely to require specialist medical care during their pregnancy due to the increased risk of adverse neonatal and maternal outcomes, finds a new study published in BJOG: An International Journal of Obstetrics and Gynaecology. The study, carried out by a team from Queen's University Belfast and Belfast Health and Social Care Trust, found that maternal obesity has significant health implications contributing to increased morbidity and mortality for both mother and baby...
Childhood Body Weight Strongly Influenced By Genes
Date: Mar-28-2013Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%. 32 genes have been identified as risk factors for obesity but previous analyses suggest that these genes alone cannot fully explain the high level of heritability in childhood obesity, as together they explain only 2% of individual differences in childhood body weight. This has led to a problem of 'missing heritability'...
Online Dietary Recommendations For Cancer Patients Inconsistent
Date: Mar-28-2013Radiation oncologists at Thomas Jefferson University Hospital are stressing the need for evidence-based, standardized guidelines on dietary recommendations for cancer patients - and with good reason. A new analysis revealed that online dietary recommendations for cancer patients, if even present on an institution's website, appear to be consistently inconsistent. A review of all 21 of the National Comprehensive Cancer Network (NCCN) member institutions found that only four provided nutritional guidelines, with seven linking to external sites...
Genetic Connections Identified In 15q Duplication Syndrome/Autism
Date: Mar-28-2013A new study published in the March issue of Autism Research from the University of Tennessee Health Science Center and Le Bonheur researchers is making the genetic connections between autism and Chromosome 15q Duplication Syndrome (Dup15q). The Memphis researchers determined that the maternally derived or inherited duplication of the region inclusive of the UBE3A gene (also known as the Angelman/Prader-Willi syndrome locus) are sufficient to produce a phenotype on the autism spectrum in all ten maternal duplication subjects...
Mugging Victims Suffer Paranoia For Months After Attack
Date: Mar-28-2013Being mugged or randomly attacked in the street often leaves people paranoid and distrustful of others long after the attack, according to a study just published. The research highlights a previously under-recognised consequence of physical assault which will help to inform therapy for those seeking help. In the study, four out of five victims reported that since the assault they were more fearful of other people than they wanted to be. Importantly the study identified what led to excessive mistrust lasting over the next six months...
Decreasing Diabetes Risk In Obese Children And Adolescents Through Vitamin D Supplementation
Date: Mar-28-2013Childhood and adolescent obesity rates in the United States have increased dramatically in the past three decades. Being obese puts individuals at greater risk for developing Type 2 diabetes, a disease in which individuals have too much sugar in their blood. Now, University of Missouri researchers found vitamin D supplements can help obese children and teens control their blood-sugar levels, which may help them stave off the disease...
Patients With ALK--Positive Non-Small Cell Lung Cancer Benefit From Ganetespib
Date: Mar-28-2013A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK--positive non-small cell lung cancer. The drug, ganetespib, may also be effective for treating patients who have become resistant to the only FDA-approved targeted therapy for this disease, crizotinib, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research...
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