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Inhibiting Akt May Be A Useful Therapeutic Strategy For Stopping Herpes Infections

Date: Mar-28-2013
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1). The finding, published online by The FASEB Journal, could lead to new drugs for treating or suppressing herpes virus infections. "We've essentially identified the molecular "key" that herpes viruses use to penetrate cell membranes and infect cells of the human body," said Betsy Herold, M.D...

Formula May Pinpoint Timing Of Final Menstrual Period, Help Menopausal Women Combat Bone Loss, Cardiovascular Risk

Date: Mar-28-2013
For women enduring hot flashes and other symptoms of menopause, a new model could better estimate the timing of the final menstrual period, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Researchers at the University of California, Los Angeles (UCLA) developed a formula using the levels of two hormones to estimate when the final menstrual period would occur...

Potential Therapeutic Treatment For Restoring Heart Function Following Heart Attack

Date: Mar-28-2013
In an animal study, researchers at the University of Washington show that it was possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions. Led by University of Washington (UW) Professor and Vice Chair of Bioengineering Michael Regnier and Dr...

If You Think Seatbelt Use Inconvenient, Consider The Inconvenience Of Being Injured, Or Worse

Date: Mar-28-2013
Since most driving is done locally, it should not be surprising that most auto accidents occur during local errands. Yet, occasional seatbelt users are more likely to buckle up for trips on high speed roads, according to an analysis of data from 100 instrumented vehicles reported in a recent issue of Accident Analysis and Prevention. If drivers and front-seat passengers used seatbelts all the time, deaths from crashes would be reduced by 45 percent, according to the National Highway Traffic Safety Administration (NHTSA). Yet 15 percent of drivers and front-seat passengers do not belt up...

Unruptured Intracranial Arteriovenous Malformations Treated With Radiosurgery

Date: Mar-28-2013
Researchers at the University of Virginia (UVA) Health System recommend radiosurgery for treating unruptured arteriovenous malformations (AVMs), because the procedure has a reasonable benefit-to-risk profile. They base this recommendation on an evaluation of clinical and radiographic outcomes in 444 patients treated with radiosurgery for unruptured AVMs at their institution. Detailed findings in this single-institution patient cohort are reported and discussed in "Radiosurgery for patients with unruptured intracranial arteriovenous malformations. Clinical article" by Dale Ding, M.D...

Valuable Organism Discovered Which Will Enable Researchers To Investigate Important Biological Questions

Date: Mar-28-2013
It's been more than fifty years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined; now they do. The new findings are published in the open access journal PLOS Biology. By identifying Tetrahymena's long-unknown mating-type genes, a team of UC Santa Barbara biologists, with research colleagues in the Institute of Hydrobiology of the Chinese Academy of Sciences, and in the J...

Association Between Early-Onset Baldness In African-American Men And Prostate Cancer

Date: Mar-28-2013
Baldness was associated with an increased risk of prostate cancer among African-American men, and risk for advanced prostate cancer increased with younger age and type of baldness, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. "We focused on African-American men because they are at high risk for developing prostate cancer and are more than twice as likely to die from prostate cancer than other groups in the United States," said Charnita Zeigler-Johnson, Ph.D...

Biologists Pinpoint The Origin Of Olfactory Nerve Cells

Date: Mar-28-2013
When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone. These sensory neurons are particularly interesting because they are the only neurons in our bodies that regenerate throughout adult life - as some of our olfactory neurons die, they are soon replaced by newborns. Just where those neurons come from in the first place has long perplexed developmental biologists...

New Compounds That Dynamically Alter Cell Signaling And Expand Options For Developing Breast Cancer Treatments

Date: Mar-28-2013
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect. These findings could lead to new strategies for treating diseases such as breast cancer...

Research Findings Contribute To Understanding Malformations Of The Heart

Date: Mar-28-2013
Viewed from the outside, our body looks completely symmetrical. However, most internal organs - including the heart - are formed asymmetrically. The right side of the heart is responsible for pulmonary circulation; the left side supplies the rest of the body. This asymmetry allows the heart to do its job effectively. In a study on zebrafish embryos, the researchers Dr. Justus Veerkamp and PD Dr. Salim Seyfried from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have now shown how the left and right sides of the heart develop differently...