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Big Role In Autism Likely Played By Misregulated Genes
Date: Mar-25-2013A genetic pathway involving proteins in the endosomes of cells appears to be misregulated in the brains of children with autism, according to a newly published statistical analysis in the journal Molecular Psychiatry. Previously the genes were shown to cause rare forms of the disease but the new study suggests they have a wider role. A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism research...
Brain Damage Can Be Averted In Oxygen-Starved Babies With Low-Cost 'Cooling Cure'
Date: Mar-25-2013When babies are deprived of oxygen before birth, brain damage and disorders such as cerebral palsy can occur. Extended cooling can prevent brain injuries, but this treatment is not always available in developing nations where advanced medical care is scarce. To address this need, Johns Hopkins undergraduates have devised a low-tech $40 unit to provide protective cooling in the absence of modern hospital equipment that can cost $12,000...
Quirky Feature Of Lyme Disease Bacteria Revealed
Date: Mar-25-2013Scientists have confirmed that the pathogen that causes Lyme Disease - unlike any other known organism - can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron. To cause disease, Borrelia burgdorferi requires unusually high levels of manganese, scientists at Johns Hopkins University (JHU), Woods Hole Oceanographic Institution (WHOI), and the University of Texas reported...
Links Explored Between Physical And Emotional Pain Relief
Date: Mar-25-2013Though we all desire relief - from stress, work, or pain - little is known about the specific emotions underlying relief. New research from the Association for Psychological Science explores the psychological mechanisms associated with relief that occurs after the removal of pain, also known as pain offset relief. This new research shows that healthy individuals and individuals with a history of self-harm display similar levels of relief when pain is removed, which suggests that pain offset relief may be a natural mechanism that helps us to regulate our emotions. 1...
Gene Identified That Is Consistently Altered In Obese Individuals
Date: Mar-25-2013Food and environment can chemically alter your gene function and scientists have identified a gene that is consistently altered in obesity. The gene LY86 was among a group of 100 genes identified as likely contributors to obesity through genome-wide association studies comparing the DNA of thousands of obese and lean individuals, said Dr. Shaoyong Su, genetic epidemiologist at the Medical College of Georgia at Georgia Regents University...
Scotland Takes Action To Tackle Relationship Between Deprivation And Heart Disease
Date: Mar-25-2013Deprivation represents the "elephant in the room" with regard to cardiovascular disease (CVD), and health care professionals have an important role to play in tackling the problem, delegates heard at a special plenary session opening the EuroHeart Care Congress in Glasgow, Scotland. The session heard how Scotland, a country considered to have the highest rates of heart disease in Western Europe, has recently taken action to address the CVD health inequalities that exist between affluent and deprived communities...
Teen Baseball Players Benefit From Docking Technique To Repair Torn Elbow Ligament
Date: Mar-25-2013A study at Hospital for Special Surgery (HSS) found that a surgical procedure known as the "docking technique" to repair a torn elbow ligament in teenage athletes yielded favorable results. The outcomes were better than those in previously published reports on reconstruction of the ulnar collateral ligament (UCL), also known as Tommy John surgery, in this age group and may be attributed to technique-specific factors, according to the study authors...
Researchers Study Use Of Dasatinib For Patients With High-Risk Myelodysplastic Syndromes
Date: Mar-25-2013Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, or acute myeloid leukemia resulting from MDS and have failed treatment with azanucleosides. The therapy may not be effective for all patients, but those with trisomy 8 chromosomal disorder have higher rates of stable disease and respond better to treatment with dasatinib, the study shows. Results of this study appeared in the March issue of Leukemia Research...
Incidental Findings In Clinical Exome And Genome Sequencing: Report Released By ACMG
Date: Mar-25-2013The American College of Medical Genetics and Genomics (ACMG) released the widely-anticipated "ACMG Recommendations for Reporting of Incidental Findings in Clinical Exome and Genome Sequencing" report at its 2013 Annual Clinical Genetics Meeting in Phoenix. The ACMG Annual Clinical Genetics Meeting is one of the largest gatherings of medical and health professionals in genetics in the world...
Homeless People Have A Disproportionately Higher Risk For Traumatic Brain Injury Compared To The General Population
Date: Mar-25-2013Homeless people and their health care providers need to know more about traumatic brain injuries to help prevent and treat such injuries, a new study has found. Homeless people have a disproportionately higher risk for TBI compared to the general population, yet little is known about the severity of those injuries, who exactly is suffering from them and what the long-term consequences are...
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