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97% Of Doctors Prescribe Placebos, UK
Date: Mar-21-2013Ninety-seven percent of doctors have prescribed placebo treatments at least one time, according to a UK survey. The research was published in PLOS ONE and was conducted by a team of experts at the Universities of Oxford and Southampton. The results demonstrated that 97% of clinicians have used impure placebo treatments and 12% have used pure placebos. Treatments that are unproven are known as impure placebos...
Paternal Age Associated With Autism Risk For Grandchildren
Date: Mar-21-2013According to new research published in JAMA Psychiatry, older men who have children are more likely to have grandchildren with autism compared to men who have children at a younger age. The research indicates that risk factors for autism build up over generations. The study was carried out by researchers from the Karolinska Institutet, King's College London's Institute of Pschiatry (IoP), and Queeensland Brain Institute. They analyzed Swedish national registers and looked at the maternal and paternal backgrounds of 5,932 people with autism as well as 30,923 healthy controls...
Functional Characteristics Of Antitumor T Cells Change With Increasing Time After Therapeutic Transfer
Date: Mar-21-2013Beneficial effect of genetically engineered antitumor T cells was transient. Functionality of T cells changed over time. Strategies are needed to sustain antitumor functionality. Scientists have characterized how the functionality of genetically engineered T cells administered therapeutically to patients with melanoma changed over time. The data, which are published in Cancer Discovery, a journal of the American Association for Cancer Research, highlight the need for new strategies to sustain antitumor T cell functionality to increase the effectiveness of this immunotherapeutic approach...
UCLA Researchers Monitor T Cell Function To Improve Melanoma Treatment
Date: Mar-21-2013UCLA and California Institute of Technology scientists from the UCLA Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research (Broad Stem Cell Research Center [BSCRC]) and the Jonsson Comprehensive Cancer Center (JCCC) led by James Heath, member of both centers, professor of molecular & medical pharmacology at UCLA and professor of chemistry at Caltech, have made an important discovery to improve a promising treatment for melanoma, an often deadly form of skin cancer. The breakthrough was published online ahead of print today in Cancer Discovery...
Medical Affairs Leaders Forum Asia, 25-26 July 2013, Singapore
Date: Mar-21-2013This event will offer an unique chance to benchmark with Asia's medical affairs experts to discuss best practices that apply in this region and an ideal opportunity to build contacts and networks for the future. Why Attend? Understand how medical affairs are at the forefront of new pharmaceutical industry commercial models and what needs to be done to maximize success. Discover what are the most intelligent ways to map and engage with KOLs and other prescribers, payers, patient groups, pharmacies and tomorrow's stakeholders...
Pharmaccess Leaders Forum, 6-8 May 2013, Vienna, Austria
Date: Mar-21-2013This event will discuss in detail viewpoints from various payers, HTAs, patient groups on the definition, measurement, validation and value of achieving various QOL improvements in several therapeutic areas. Furthermore, there will also be perspectives from the pharma industry of how they overcame challenges in researching and demonstrating QOL improvements to provide extra value to payers, physicians and patients...
Virus-Based Melanoma Drug Shows Promise In Trial
Date: Mar-21-2013For the first time in a late stage trial, a virus-based cancer drug is showing some promising early results. The news that Amgen's melanoma drug talimogene laherparepvec (TVEC) has met the primary goal of a Phase 3 trial may revive interest in what has proved to be a rather elusive drug technology. The company reports that 16% of the patients who received TVEC experienced tumor shrinkage that persisted for six months compared with only 2% in a control group that received a treatment based on GM-CSF, a protein that stimulates the immune system...
Study: Young People In Abusive Dating Relationships Are Happier When Relationship Ends Than They Expected
Date: Mar-21-2013Young adults in abusive and controlling dating relationships were happier when their relationships were over than they expected to be, according to a Purdue University study. "It wasn't a surprise that these people were better off than they had expected when their relationship ended, but what was interesting was that there was a disconnect between how they actually felt and how they had anticipated feeling months earlier," said Ximena Arriaga (pronounced He-MEN-ah Ah-ree-AH-ga), an associate professor of psychological sciences who studies dating relationships...
Scientists Unlock Hidden Potential Of Cutting-Edge Cancer Drugs
Date: Mar-21-2013A class of cutting-edge cancer drugs could keep patients alive for much longer than they do now following a major new discovery about exactly how they attack tumours. Scientists have hailed the finding "unexpected and exciting". The drugs, known as kinase inhibitors, are some of the most heralded of the new kind of targeted therapies, with 25 already in use and around 400 under development. They treat 5,000-10,000 patients in the UK each year, with that number set to grow as more are approved for use...
Scientists Identify Gene Fault With A Domino Effect On Cancer Risk
Date: Mar-21-2013Scientists have identified a brand new genetic mechanism that raises the risk of cancer via a domino effect on DNA - with one gene fault triggering a second, cancer-causing mutation. A team at The Institute of Cancer Research, London, found some cancer patients inherit a weak point in their DNA that appears to leave one of their chromosomes vulnerable to snapping and becoming mutated. Researchers hailed the finding - published in Nature Genetics today (Sunday) - as a "very important discovery" that opens up new avenues for cancer treatment and prevention...
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