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A Better 'Mousetrap' Discovered In Fruit Flies Might Stop A Human Cancer-Driving Kinase In Its Tracks
Date: Mar-15-2013A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers at the Stowers Institute for Medical Research to the discovery of a atypical protein that lures, traps, and inactivates the powerful Polo kinase, widely considered the master regulator of cell division. Its human homolog, Polo-like kinase-1 (Plk1), is misregulated in many types of cancer. Stowers Investigator and senior author R. Scott Hawley, Ph.D...
Age-Related Changes Found In How Autism Affects The Brain
Date: Mar-15-2013Newly released findings from Bradley Hospital published in the Journal of the American Academy of Child & Adolescent Psychiatry have found that autism spectrum disorders (ASD) affect the brain activity of children and adults differently. In the study, titled "Developmental Meta-Analysis of the Functional Neural Correlates of Autism Spectrum Disorders," Daniel Dickstein, M.D., FAAP, director of the Pediatric Mood, Imaging and Neurodevelopment Program at Bradley Hospital, found that autism-related changes in brain activity continue into adulthood...
Paving The Way For Greater Use Of Ancient Medical Knowledge
Date: Mar-15-2013Scientists are reporting an advance toward overcoming a major barrier to tapping the potential of traditional Chinese medicine (TCM) and India's Ayurvedic medicine in developing new and more effective modern drugs. Their report appears in ACS' Journal of Chemical Information and Modeling. Andreas Bender and colleagues explain that TCM has made key contributions to modern medicine...
Controlling Pesticide Exposure In Children
Date: Mar-15-2013New research on household pesticide contamination emphasizes the need for less reliance on pesticides and more emphasis on neatness, blocking cracks where insects can enter and other so-called "integrated pest management" (IPM) measures, scientists have concluded. Their study appears in the ACS' journal Environmental Science & Technology. Chensheng Lu and colleagues cite previous studies showing that urban, low-income, multifamily, public housing dwellings are prone to severe pest infestation problems...
Younger Doctors More Likely To Train And Work Closer To Home
Date: Mar-15-2013Younger doctors are more likely than older generations to train and work in the same region as their home before entering medical school. New research published in the Journal of the Royal Society of Medicine investigating the geographical mobility of UK-trained doctors, reveals that 36% attended a medical school in their home region. 34% of hospital consultants and GP partners settled in the same region as their home before entering medical school. The geographical distribution of doctors is an important factor in the equitable distribution of health services...
Researchers Find Cancer Cell Weakness, A Breakthrough In The Battle Against Leukemia
Date: Mar-15-2013Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments. The research team has demonstrated that leukaemic cells can be eradicated by removing a carbohydrate modification displayed on the cell's surface. Director of Griffith University's Institute for Glycomics, Professor Mark von Itzstein is the Australian team leader...
Old Drug Offers Hope For New Autism Treatment
Date: Mar-15-2013Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications in a mouse model of autism, reversing symptoms of the devastating disorder. The findings are published in the journal PLOS ONE...
Vitamin D Supplements May Help African Americans Lower Blood Pressure
Date: Mar-15-2013Vitamin D supplements significantly reduced blood pressure in the first large controlled study of African-Americans, researchers report in the American Heart Association journal Hypertension. In the prospective trial, a three-month regimen of daily vitamin D increased circulating blood levels of vitamin D and resulted in a decrease in systolic blood pressure ranging from .7 to four mmHg (depending upon the dose given), compared with no change in participants who received a placebo...
Aggregation In CJD Likely Leads To Iron Imbalance And Brain Cell Death
Date: Mar-15-2013An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found. The breakthrough follows discoveries that certain proteins found in the brains of Alzheimer's and Parkinson's patients also regulate iron. The results suggest that neurotoxicity by the form of iron, called redox-active iron, may be a trait of neurodegenerative conditions in all three diseases, the researchers say...
People Experience Time As If They're Moving Toward The Future And Away From The Past
Date: Mar-15-2013We say that time flies, it marches on, it flows like a river - our descriptions of time are closely linked to our experiences of moving through space. Now, new research suggests that the illusions that influence how we perceive movement through space also influence our perception of time. The findings provide evidence that our experiences of space and time have even more in common than previously thought...
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