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On-Pump Bypass & Off-Pump Have Similar Outcomes After 1 Year
Date: Mar-12-2013Patients who undergo heart bypass surgery without a heart-lung machine do just as well after one year as those whose hearts were connected to a pump during the procedure. The finding came from a new study presented at the American College of Cardiology's 62nd Annual Scientific Session. CORONARY is a global, multi center trial comparing on-pump (with a heart-lung machine) to off-pump bypass surgery. The study, the largest yet to compare the two methods, consisted of 4,752 patients who were about to undergo a bypass procedure...
After Fifth Dose Of Whooping Cough Vaccine Immunity Wanes
Date: Mar-12-2013Even though high numbers of the vaccine for whooping cough have been administered throughout the United States, incidence of pertussis is still at its highest in years. One reason could be that after the fifth dose is administered, immunity starts to wane. (Pertussis is the medical term for whooping cough.) Research from the U.S...
233 Million Women Will Be Lacking Contraception In 2015
Date: Mar-12-2013Despite the increase in people using contraceptives over the past few decades, a recent study published in The Lancet reports that by 2015 the demand for contraception will increase by a further 62 million, which translates into 233 million women with partners who will not have access to contraception. The researchers, from the National University of Singapore, conducted a study that evaluated the extent of contraceptive use among women aged 15 to 49. They analyzed previous data over the past two decades related to contraceptive use from over 194 countries...
PPPs Standing Behind The Growth Of Pharma R&D - 2nd Annual Open Innovation In Pharmaceutical R&D, 15-16 May 2013, Amsterdam
Date: Mar-12-2013In the past years, many blockbuster drugs lost their patents. To avoid the resulting decline in sales, pharma companies had to start looking for new wonder drugs. Considering the main factors such as time horizon and financial resources, they found the solution in public private partnerships. Understanding future opportunities and challenges for further joint industry-academia collaboration in drug discovery and development, big pharma already launched academic medical centres...
People Eat More, Gain Weight With Less Sleep
Date: Mar-12-2013When people don't get enough sleep they tend to eat more, causing them to gain weight. This was the conclusion of a new study led by University of Colorado Boulder in the US that was published online this week in the Proceedings of the National Academy of Sciences. The researchers found that volunteers who slept only 5 hours a night during a working week put on nearly two pounds (0.8 kg) in weight if they had unlimited access to food...
New International Study Investigating Inflammatory Bowel Disease
Date: Mar-12-2013The University of Manchester is leading a 12 million euro systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease. Professor Werner Müller from the Faculty of Life Sciences is the Scientific Co-ordinator for the network called SysmedIBD. It includes universities and companies from the UK, Germany, the Netherlands, Israel and New Zealand...
Signaling Molecule May Help Stem Cells Focus On Making Bone Despite Age, Disease
Date: Mar-12-2013A signaling molecule that helps stem cells survive in the naturally low-oxygen environment inside the bone marrow may hold clues to helping the cells survive when the going gets worse with age and disease, researchers report. They hope the findings, reported in�PLOS ONE, will result in better therapies to prevent bone loss in aging and enhance success of stem cell transplants for a wide variety of conditions from heart disease to cerebral palsy and cancer...
Niacin And Laropiprant Combo Shows No Benefits, Has Some Harmful Effects In Patients With Vascular Disease
Date: Mar-12-2013A highly anticipated study evaluating a combination of the vitamin niacin with the anti-flushing agent laropiprant finds the therapy provides no benefit to and may even be harmful for patients with vascular disease, according to research presented at the American College of Cardiology's 62nd Annual Scientific Session. Detailed trial data is presented here for the first time...
Cancer Cells Communicate With Each Other In Order To Move As A Group
Date: Mar-12-2013Researchers at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC) have discovered a new mechanism that allows some cells in our body to move together, in some ways like the tortoise formation used by Roman soldiers depicted in the Asterix series. Collective cell migration is an essential part of our body's growth and defense system, but it is also used by cancerous cells to disseminate efficiently in the body...
Many Colonoscopies For Seniors May Be Inappropriate
Date: Mar-12-2013A considerable percentage of colonoscopies that are performed on seniors could be potentially inappropriate, researchers from the University of Texas Medical Branch, Galveston, reported in JAMA Internal Medicine. Kristin M. Sheffield, Ph.D., and team set out to determine how frequently potentially inappropriate colonoscopies are performed on elderly Medicare beneficiaries in Texas. They also aimed to examine variations among doctors and across geographic regions. The researchers gathered and examined data from Medicare claims in Texas, as well as a sample from the rest of the USA...
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