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Prior To Coronary Intervention Procedure, Validated Pre-Procedure Risk Score Reduces Bleeding Complications

Date: Mar-12-2013
A clinical decision support tool helped physicians identify patients at high risk of bleeding complications prior to undergoing a coronary intervention procedure and helped guide the use of bleeding avoidance strategies, leading to less complications and a shorter hospital stay, according to a study presented at the American College of Cardiology Scientific Sessions. More than 1.3 million percutaneous coronary interventions (PCIs) are performed each year in the United States. Bleeding during and after these procedures is a common risk (3 - 6%)...

The Protective Effect Of Diabetic Medication Against Developing Heart Failure

Date: Mar-12-2013
A class of medications commonly prescribed to lower blood sugar in diabetic patients appears to protect them from developing heart failure, according to a study at Henry Ford Hospital in Detroit. "People with diabetes are at risk for developing heart failure," says Henry Ford researcher and cardiologist David Lanfear, M.D., lead author of the study. "Diabetic adults die of heart disease two to four times more than those without diabetes. "Our study data suggest that diabetic patients taking a particular class of medications are less likely to develop heart failure," adds Dr. Lanfear...

Study On Treatment For Heart Attack Patients

Date: Mar-12-2013
A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal. Presented in San Francisco at the prestigious American cardiology conference, these findings show great promise...

National NIH Collaboration To Find Parkinson's Biomarkers And Open Vast Data Sharing Opportunities

Date: Mar-12-2013
Last month, the National Institutes of Health announced a new collaborative initiative that aims to accelerate the search for biomarkers -- changes in the body that can be used to predict, diagnose or monitor a disease -- in Parkinson's disease, in part by improving collaboration among researchers and helping patients get involved in clinical studies. As part of this program, launched by the National Institute of Neurological Disorders and Stroke (NINDS), part of the NIH, Clemens Scherzer, MD, a neurologist and researcher at Brigham and Women's Hospital (BWH), was awarded $2...

Generics Hold Cost Of Medicines In Check For America Even As Specialty Drug Prices Soar

Date: Mar-12-2013
GPhA Warns Against Legislative Efforts to Undermine Savings For the first time in 20 years, the cost of treating common ailments like high cholesterol, diabetes and high blood pressure dropped in 2012 due to the increased availability of lower priced generic prescription drugs. A report released earlier this week by pharmacy benefits manager Express Scripts Inc...

Largely Present In Women, 'Broken Heart Syndrome' Is Often Triggered By Stress

Date: Mar-12-2013
Even though a newly recognized cardiomyopathy, which mainly impacts women, is typically treatable, Tako-tsubo cardiomyopathy can also be deadly when compounded by other co-morbidities, such as heart failure, according to a study presented at the American College of Cardiology (ACC) Scientific Sessions. This condition, formally known as Tako-tsubo cardiomyopathy (TTC) and informally known as stress cardiomyopathy or broken heart syndrome, has abrupt onset of symptoms and is characterized by a distinctive left ventricular (LV) contraction profile...

Selling Body Parts To Repay Loans

Date: Mar-12-2013
Selling a kidney or part of one's liver to pay off loans is becoming increasingly common in Bangladesh, where desperate villagers are being exploited by human organ traffickers, a Michigan State University researcher has found. In a small village near Joypurhat in northern Bangladesh, Selina Akther sold a kidney to repay her husband's microcredit loans and now suffers from daily pain and the scorn of fellow villagers. Her husband, brother-in-law and father-in-law also sold a kidney...

Detailed Blood Analysis May Be Possible Via Temp-Controlled 'Nanopores'

Date: Mar-12-2013
Tiny biomolecular chambers called nanopores that can be selectively heated may help doctors diagnose disease more effectively if recent research by a team at the National Institute of Standards and Technology (NIST), Wheaton College, and Virginia Commonwealth University (VCU) proves effective. Though the findings* may be years away from application in the clinic, they may one day improve doctors' ability to search the bloodstream quickly for indicators of disease - a longstanding goal of medical research...

Biophysicists Have Shown How A Defect In A Mechanosensitive Ion Channel Can Cause Disease

Date: Mar-12-2013
A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the Proceedings of the National Academy of Sciences by University at Buffalo scientists and colleagues. The research team was led by Frederick Sachs, PhD, SUNY Distinguished Professor in the UB Department of Physiology and Biophysics, who discovered in the 1980s that some ion channels are mechanosensitive, that is, they convert mechanical stress into electrical or biochemical signals...

Recommendations Expanded For Use Of Electronic Health Records In Pediatrics

Date: Mar-12-2013
To speed development and adoption of electronic health records (EHRs) for pediatrics, a group of experts from industry, academia and government convened by the National Institute of Standards and Technology (NIST) has focused its attention on three key audiences - records-system vendors and developers, small-group pediatric medical practices and children's hospitals...