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Exposure To Tobacco Smoke Linked To Signs Of Heart Disease
Date: Mar-11-2013Nonsmokers, beware. It seems the more you are exposed to secondhand tobacco smoke - whether it was during your childhood or as an adult, at work or at home - the more likely you are to develop early signs of heart disease, according to research presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers found that 26 percent of people exposed to varying levels of secondhand smoke had signs of coronary artery calcification (CAC), compared to 18.5 percent in the general population...
Identifying Mechanism Behind Treatment Resistance In Melanoma Suggests Possible Strategy For Improvement
Date: Mar-11-2013A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, which will be published in Cancer Cell and have been released online, suggest a strategy to improve the effectiveness of currently available targeted therapies. "We were surprised to find that melanoma cells treated with the BRAF inhibitor vemurafenib dramatically change the way they produce energy to stay alive," says David E...
Pediatric, Family Medicine Practices Unprepared To Become Medical Homes For Children
Date: Mar-11-2013Primary care practices around the country are being encouraged and even paid to become "medical homes," but small practices might be at a significant disadvantage in this race to improve health care for children, according to a new study by child health experts at C.S. Mott Children's Hospital. Efforts around the country to improve health care for children have increasingly focused on the medical home as a model to make primary care practices more accessible, comprehensive, and focused on quality improvement...
Hypocretin Administration May Elevate Both Mood And Alertness
Date: Mar-11-2013What makes us happy? Family? Money? Love? How about a peptide? The neurochemical changes underlying human emotions and social behavior are largely unknown. Now though, for the first time in humans, scientists at UCLA have measured the release of a specific peptide, a neurotransmitter called hypocretin, that greatly increased when subjects were happy but decreased when they were sad...
Wearing A Surgical Mask Significantly Decreases The Presence Of Flu Virus In Airborne Droplets From Exhaled Breath
Date: Mar-11-2013People may more likely be exposed to the flu through airborne virus than previously thought, according to new research from the University of Maryland School of Public Health. The study also found that when flu patients wear a surgical mask, the release of virus in even the smallest airborne droplets can be significantly reduced. "People are generally surprised to learn that scientists don't know for sure how flu spreads," says Donald Milton, M.D., Dr.P.H...
X-Ray Imaging Sheds New Light On Bone Damage By Illuminating Fractures
Date: Mar-11-2013From athletes to individuals suffering from osteoporosis, bone fractures are usually the result of tiny cracks accumulating over time -- invisible rivulets of damage that, when coalesced, lead to that painful break. Using cutting-edge X-ray techniques, Cornell University researchers have uncovered cellular-level detail of what happens when bone bears repetitive stress over time, visualizing damage at smaller scales than previously observed. Their work could offer clues into how bone fractures could be prevented...
New Technology Improves On Gene Switching
Date: Mar-11-2013Scientists at UC San Francisco have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs and tissues. The strategy borrows from the molecular toolbox of bacteria, using a protein employed by microbes to fight off viruses, according to the researchers, who describe the technique in the current issue of Cell. Turning off genes is a major goal of treatments that target cancer and other diseases...
Gastric Artery Chemical Embolization Lowers Levels Of 'Hunger Hormone,' Leads To Weight Loss
Date: Mar-11-2013Suppressing a hunger-stimulating hormone with a minimally invasive procedure was safe in humans and led to significant weight loss for at least six months in a small preliminary study presented at the American College of Cardiology's 62nd Annual Scientific Session. More than two-thirds of American adults are overweight or obese, conditions that total more than $147 billion in medical costs each year. Excess weight also increases the risk for other conditions, such as high blood pressure, high cholesterol and type 2 diabetes...
More Women With CAD Need To Be Referred For Cardiac Rehab
Date: Mar-11-2013Women with coronary artery disease who completed a 12-week cardiac rehabilitation program were two-thirds less likely to die compared to those who were not referred to the program. In addition, the mortality benefit derived from this evidence-based program appears to be much more striking in women than men with the same condition, yet referrals and attendance among women fall short, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session...
Breakthrough In Anti-Ageing Research
Date: Mar-11-2013Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher. The work, published in the March 8 issue of Science, finally proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans. The paper shows all of the 117 drugs tested work on the single enzyme through a common mechanism. This means that a whole new class of anti-ageing drugs is now viable, which could ultimately prevent cancer, Alzheimer's disease and type 2 diabetes...
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