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Study: Barriers To Prostate Cancer Care: Affordable Care Is Not Enough
Date: Mar-07-2013A combination of financial, cultural and communication barriers plays a role in preventing underserved Latino men with prostate cancer from accessing the care and treatment they need, according to a new study by researchers at the UCLA School of Nursing. The study, "Barriers to Prostate Cancer Care: Affordable Care Is Not Enough," is published in the March issue of the peer-reviewed journal Qualitative Health Research. According to the American Cancer Society, prostate cancer is the most commonly diagnosed cancer among Latino men...
Researchers Uncover Veritable 'Assembly Plants' In Mitochondria, The Organelles Responsible For Energy Production
Date: Mar-07-2013Mitochondria, which are probably derived from distant bacterial ancestors incorporated into our cells, have their own DNA. However, we know little about how these organelles, which convert oxygen and consumed nutrients into energy, regulate the expression of their own genes. Jean-Claude Martinou, professor at the University of Geneva (UNIGE), Switzerland, and his team, have discovered the existence of compartments at the heart of mitochondria, consisting of hundreds of different proteins...
Increasing Resistance To First Line Anti-Malarial Drugs On The Thai-Myanmar Border
Date: Mar-07-2013Early diagnosis and treatment with antimalarial drugs (ACTs - artemisinin based combination treatments) has been linked to a reduction in malaria in the migrant population living on the Thai-Myanmar border, despite evidence of increasing resistance to ACTs in this location, according to a study by international researchers published in this week's PLOS Medicine. These findings are important as this study suggests that alternative treatments are urgently needed to replace the failing first line drug regimen (mefloquine and artesunate)...
Mathematical Model Of Disease Transmission Can Estimate The Pandemic Potential Of A Zoonotic Virus Like Swine Flu
Date: Mar-07-2013A simple new method better assesses the risks posed by emerging zoonotic viruses (those transmissible from animals to humans), according to a study published in PLOS Medicine this week. Dr. Simon Cauchemez and colleagues from Imperial College London in the UK and the Centers for Disease Control and Prevention in the US show that the new tool can produce transmissibility estimates for swine flu (the H3N2v-M virus), allowing researchers to better evaluate the possible pandemic threat posed by this virus...
Prostate Cancer Visualized Using Novel Small Molecules
Date: Mar-07-2013Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine. The imaging agents -123I-MIP-1072 and 123I-MIP-1095 - were shown to have a high sensitivity of lesion detection in bone, soft tissue and the prostate gland with minimal retention in non-target tissue. An estimated 238,500 men will be diagnosed with prostate cancer in 2013, and 29,700 will die from the disease...
Wide Disparities In Access To Latest Rheumatoid Arthritis Drugs Across Europe
Date: Mar-07-201326 countries can't afford certain disease modifying drugs, so excluding 320 million people The cost of one year 's treatment of rheumatoid arthritis with new generation drugs is more than the per capita gross domestic product (GDP) of 26 European countries, reveals research published online in the Annals of the Rheumatic Diseases. This means that 320 million people - 40% of Europe's population - who could benefit from treatment with disease modifying drugs (DMARDs) would struggle to get access to them, say the researchers...
Internet Searches Can Identify Drug Safety Issues Well Ahead Of Public Alerts
Date: Mar-07-2013Analysis of anonymised web log data could be used as early warning system Internet searches on health symptoms can be used to identify drug side effects and could be used to develop a new kind of early warning system to boost drug safety, indicates a study published online in the Journal of the American Medical Informatics Association. The authors base their findings on an analysis of the anonymised search logs of millions of US web users, who agreed to install a browser add-on and share their online searches with Microsoft throughout 2010...
Genome Police May Be Undermined By Selfish Gene
Date: Mar-07-2013Biologists have been observing the "selfish" genetic entity segregation distorter (SD) in fruit flies for decades. Its story is a thriller among molecules, in which the SD gene destroys maturing sperm that have a rival chromosome. A new study reveals a tactic that gives SD's villainy an extra edge. For a bunch of inanimate chemical compounds, the nucleic and amino acids caught up in the infamous "selfish" segregation distorter (SD) saga have put on quite a soap opera for biologists since the phenomenon was discovered in fruit flies 50 years ago...
Fruit Flies Lacking TORC2 Show Defective Long-Term Memory Storage
Date: Mar-07-2013Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory - the introduction - and converted it into a long-term one. The molecular key to this activity is mTORC2 (mammalian target of rapamycin complex 2), according to researchers at Baylor College of Medicine in an article that appeared online in the journal Nature Neuroscience. "Memory consolidation is a fundamental process," said Dr...
Discovery Of A Virus Which Infects A Host That Has A Non-Standard Nuclear Genetic Code
Date: Mar-07-2013Among eukaryotes with modified nuclear genetic codes, viruses are unknown. Until now it had been believed that the modifications to the genetic code effectively prevented new viral infections. However, researchers have now reported the first example of a virus that can be shown to have crossed the boundary from organisms using the standard genetic code to those with an alternate genetic code. "The finding is significant because it means that virus-host co-evolution after a genetic code shift can be more extensive than previously thought", said researcher Derek J...
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