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New Method For Researching The Anopheles Albimanus Mosquito - Another Spreader Of Human Malaria
Date: Mar-04-2013Researchers at the Johns Hopkins Malaria Research Institute have developed a new method for studying the complex molecular workings of Anopheles albimanus, an important but less studied spreader of human malaria. An. albimanus carries Plasmodium vivax, the primary cause of malaria in humans in South America and regions outside of Africa. Unlike Anopheles gambiae, the genome of the An. albimanus mosquito has not been sequenced and since these two species are evolutionarily divergent, the genome sequence of An. gambiae cannot serve as an appropriate reference...
PTSD A Problem For Nearly 1 In 4 Women Newly Diagnosed With Breast Cancer
Date: Mar-04-2013A study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) at NewYork-Presbyterian/Columbia University Medical Center, has found that nearly one in four women (23 percent) newly diagnosed with breast cancer reported symptoms consistent with post-traumatic stress disorder (PTSD) shortly after diagnosis, with increased risk among black and Asian women. The research has been e-published ahead of print in the Journal of the National Cancer Institute...
New Method To Help Simplify The Study Of Brain Pathologies
Date: Mar-04-2013Scientists from the Johns Hopkins University School of Medicine in Baltimore, MD have developed a new way to identify heterogeneous brain cells by looking at epigenetic variation (the heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence). With this publicly available new method (named "CETS"), it will be possible to generate neuronal profiles from DNA methylation data, which will simplify the study of several brain pathologies, including depression and age-associated disorders...
New Mouse Model Could Lead To Improved Treatment For Early Stage Alzheimer's
Date: Mar-04-2013Researchers at the University of Florida and The Johns Hopkins University have developed a line of genetically altered mice that model the earliest stages of Alzheimer's disease. This model may help scientists identify new therapies to provide relief to patients who are beginning to experience symptoms. The researchers report their findings in the current issue of The Journal of Neuroscience...
Appropriate Use Criteria For ICDs And CRT
Date: Mar-04-2013The American College of Cardiology and the Heart Rhythm Society, along with key specialty societies, have released appropriate use criteria for implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy (CRT). The document provides assessed levels of appropriateness for implanting the devices in 369 real-life clinical scenarios, with the goal of enhancing physician and patient decision making and improving care and health outcomes...
Mapping Of Sea Lamprey Genome Offers Improved Understanding Of Neurodegenerative Diseases In Humans
Date: Mar-04-2013Beginning in 2004, a group of scientists from around the globe, including two University of Oklahoma faculty members, set out to map the genome of the sea lamprey. The secrets of how this jawless vertebrate separated from the jawed vertebrates early in the evolutionary process will give insight to the ancestry of vertebrate characters and may help investigators more fully understand neurodegenerative diseases in humans. David McCauley, associate professor in the Biology Department in the OU College of Arts and Sciences, and Sandra W...
How Gold Particles, DNA And Water Have The Potential To Shape The Future Of Medicine
Date: Mar-04-2013A diagnostic "cocktail" containing a single drop of blood, a dribble of water, and a dose of DNA powder with gold particles could mean rapid diagnosis and treatment of the world's leading diseases in the near future. The cocktail diagnostic is a homegrown brew being developed by University of Toronto's Institute of Biomaterials and Biomedical Engineering (IBBME) PhD student Kyryl Zagorovsky and Professor Warren Chan that could change the way infectious diseases, from HPV and HIV to malaria, are diagnosed. And it involves the same technology used in over-the-counter pregnancy tests...
Innovative Strategy Pinpoints Genes Underlying Cardiovascular Disease Risk
Date: Mar-04-2013Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers from the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, through the joint Molecular Medicine Partnership Unit (MMPU), are taking these results one step further by pinpointing the exact genes that could have a role in the onset of the disease. Their findings are published in the Public Library of Science (PLoS) Genetics...
Novel Wireless Brain Sensor
Date: Mar-04-2013A team of neuroengineers based at Brown University has developed a fully implantable and rechargeable wireless brain sensor capable of relaying real-time broadband signals from up to 100 neurons in freely moving subjects. Several copies of the novel low-power device, described in the Journal of Neural Engineering, have been performing well in animal models for more than year, a first in the brain-computer interface field. Brain-computer interfaces could help people with severe paralysis control devices with their thoughts...
Pregnant Moms Addicted To Junk Food May Pass Addiction Onto Offspring
Date: Mar-04-2013Here's another reason why a healthy diet during pregnancy is critical to the future health of your children: New research published in the March 2013 issue of The FASEB Journal, suggests that pregnant mothers who consume junk food actually cause changes in the development of the opioid signaling pathway in the brains of their unborn children. This change results in the babies being less sensitive to opioids, which are released upon consumption of foods that are high in fat and sugar...
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