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Molecular System Identified That Could Help Develop Treatments For Alzheimer's Disease

Date: Feb-25-2013
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases. An important aspect of chronic neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's or prion disease, is the generation of an innate inflammatory reaction within the brain...

Total Eradication Of Malaria Has Longlasting Benefits For Many Countries

Date: Feb-25-2013
Many nations battling malaria face an economic dilemma: spend money indefinitely to control malaria transmission or commit additional resources to eliminate transmission completely. A review of malaria elimination conducted by researchers at the Johns Hopkins Malaria Research Institute and other institutions suggests stopping malaria transmission completely has longlasting benefits for many countries and that once eliminated, the disease is unlikely to reemerge over time...

Adult Life Expectancy Dramatically Increased By Scale-Up Of HIV Treatment In Rural South Africa

Date: Feb-25-2013
The large antiretroviral treatment (ART) scale-up in a rural community in KwaZulu-Natal, South Africa, has led to a rapid and dramatic increase in population adult life expectancy - a gain of 11.3 years over eight calendar years (2004-2011) - and the benefit of providing ART far outweighs the cost, according to new research from Harvard School of Public Health (HSPH)...

Stopping Flu Virus In Its Tracks

Date: Feb-25-2013
A new class of influenza drug has been shown effective against drug-resistant strains of the flu virus, according to a study led by University of British Columbia researchers. Published online in the journal Science Express, the study details the development of a new drug candidate that prevents the flu virus from spreading from one cell to the next. The drug is shown to successfully treat mice with lethal strains of the flu virus. In order to spread in the body, the flu virus first uses a protein, called hemagglutinin, to bind to the healthy cell's receptors...

Publication Of First Comprehensive Literature Review On The Burden Of Liver Disease In Europe: EASL

Date: Feb-25-2013
Major progress has been made in the past 30 years in the knowledge and management of liver disease, yet approximately 29 million Europeans still suffer from a chronic liver condition. The European Association for the Study of the Liver (EASL) has unveiled its new publication The burden of liver disease in Europe: a review of available epidemiological data. Key findings in the report suggest that alcohol consumption, viral hepatitis B and C and metabolic syndromes related to overweight and obesity are the leading causes of cirrhosis and primary liver cancer in Europe...

The Long-Term Efficacy Of Minimally Invasive Therapy For Patients With Barrett's Esophagus

Date: Feb-24-2013
According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, patients with Barrett's esophagus and early or pre-cancerous cells have been shown to significantly benefit from minimally invasive therapy delivered through an endoscope - a medical instrument used to look inside an organ or cavity in the body. Until recently, patients with these conditions were treated by surgery to remove the whole esophagus...

Red Wine And Red Grapes Help Protect Against Hearing Loss And Cognitive Decline

Date: Feb-24-2013
Red wine and red grapes contain resveratrol, a substance which appears to protect against hearing loss and cognitive decline, researchers from the Henry Ford Hospital, Detroit, reported in Otolaryngology-Head and Neck Surgery. In an animal experiment, the scientists found that laboratory rats would suffer less from the long-term effects of noise-induced hearing loss if they consumed resveratrol before listening to extended periods of loud noise. Study lead author Michael D...

Success Of Worksite-Based Weight Loss Intervention In Conjunction With Behavioral Counseling

Date: Feb-24-2013
Workplace-based programs that include dietary advice coupled with behavioral counseling appear to be a promising approach for men and women with significant weight loss goals, based on the results of a pilot study conducted by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University. Employees enrolled in the intervention arm of a randomized controlled trial lost on average, 18 pounds over a six-month period compared to a two pound weight gain in a control group...

New Gene Associated With Alzheimer's Plaques Identified In Genome-Wide Imaging Study

Date: Feb-24-2013
A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE. A national research team, led by scientists at the Indiana University School of Medicine, reported the results of the study in an article in Molecular Psychiatry posted online...

In Prevention Of Hospital-Acquired Infection, Informatics Tools Are Underutilized

Date: Feb-24-2013
Advances in electronic medical record systems and health information exchange are shifting efforts in public health toward greater use of information systems to automate disease surveillance, but a study from the Regenstrief Institute has found that these technologies' capabilities are underutilized by those on the front lines of preventing and reporting infections...