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New Therapeutics Developed That Could Accelerate Wound Healing
Date: Feb-22-2013In "before" and "after" photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin. What we don't appreciate is the vital role that our own natural biomolecules play in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells...
Fusing Engineering And Mathematical Principles Helps Create Dynamic Brain Models
Date: Feb-22-2013Models of the human brain, patterned on engineering control theory, may some day help researchers control such neurological diseases as epilepsy, Parkinson's and migraines, according to a Penn State researcher who is using mathematical models of neuron networks from which more complex brain models emerge. "The dual concepts of observability and controlability have been considered one of the most important developments in mathematics of the 20th century," said Steven J. Schiff, the Brush Chair Professor of Engineering and director of the Penn State Center for Neural Engineering...
Tests In Mice & Human Blood Cells Look Promising For Using Old Antidepressant To Treat Sickle Cell Disease
Date: Feb-22-2013An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team from the University of Michigan Medical School. The discovery that tranylcypromine, or TCP, can essentially reverse the effects of sickle cell disease was made by U-M scientists who have spent more than three decades studying the basic biology of the condition, with funding from the National Institutes of Health...
For Colorectal Cancer Prevention, Resistant Starch Should Be On The Menu
Date: Feb-22-2013As the name suggests, you can't digest resistant starch so it ends up in the bowel in pretty much the same form it entered your mouth. As unlovely as that seems, once in the bowel this resistant starch does some important things, including decreasing bowel pH and transit time, and increasing the production of short-chain fatty acids. These effects promote the growth of good bugs while keeping bad bugs at bay...
Poverty May Be A More Powerful Predictor Of Problem Behavior Than The Immediate Parenting Context
Date: Feb-22-2013Some infants raised in poverty exhibit physical traits that make them more vulnerable to poor caregiving, according to new research published in Psychological Science*, a journal of the Association for Psychological Science. The combination of physiological vulnerability and poor caregiving may lead these children to show increased problem behaviors later in childhood. For infants growing up in poverty, the ability to adapt and regulate - both biologically and behaviorally - in response to various environmental pressures seems to be critical for successful development...
Rare Examination Of Interventions In Treating African-Americans With Substance Abuse
Date: Feb-22-2013New research out of the University of Cincinnati reveals a relatively rare look into the success of substance abuse treatment programs for African-Americans. Researchers report that self-motivation could be an important consideration into deciding on the most effective treatment strategy. The study led by Ann Kathleen Burlew, a UC professor of psychology, and LaTrice Montgomery, a UC assistant professor of human services, is published online this week in Psychology of Addictive Behaviors...
Synaptic Molecule Works Differently Than Thought; May Mean New Therapeutic Targets For Treating Alzheimer's Disease
Date: Feb-22-2013In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer's disease impacts that receptor and weakens synaptic connections between brain cells. The findings are published in the early edition of the Proceedings of the National Academy of Sciences...
Malaria Maps Altered By New Approach
Date: Feb-22-2013Identifying areas of malarial infection risk depends more on daily temperature variation than on the average monthly temperatures, according to a team of researchers, who believe that their results may also apply to environmentally temperature-dependent organisms other than the malaria parasite. "Temperature is a key driver of several of the essential mosquito and parasite life history traits that combine to determine transmission intensity, including mosquito development rate, biting rate, development rate and survival of the parasite within the mosquito," said Justine I...
Most Owners Are Unaware That Their Cat's Behavior Is Due To The Painful Condition Osteoarthritis
Date: Feb-22-2013Scientists at the University of Montreal's Quebec Research Group in Animal Pharmacology have found a way to recognize and treat osteoarthritis in cats - a condition that the owner might not notice and that can make even petting painful. "Osteoarthritis frequently affects cats' elbows, backs and hips and joints in the hind limbs, and its prevalence increases dramatically with age. More than 80 % of cats older than 11 years old have it," explained lead author Eric Troncy of the university's Faculty of Veterinary Medicine...
Promising New Compound For Battling Kidney Cancer
Date: Feb-22-2013Chemists at the University of California, Riverside have developed a compound that holds much promise in the laboratory in fighting renal (kidney) cancer. Named TIR-199, the compound targets the "proteasome," a cellular complex in kidney cancer cells, similar to the way the drug bortezomib, approved by the Food and Drug Administration, targets and inhibits the proteasome in multiple myeloma cells, a cancer coming from bone marrow...
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