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Aussie First For Monash IVF Team
Date: Feb-12-2013In an Australian first, a woman has become pregnant after being reimplanted with ovarian tissue she opted to have frozen 7 years earlier before treatment for cancer, according to a case report published online today in the Medical Journal of Australia. The woman, who was 37 when her breast cancer was found, opted for the cryopreservation procedure before starting gonadotoxic chemotherapy which would severely reduce her chances of falling pregnant...
Tumour Blood Vessels Prevent The Spread Of Cancer Cells
Date: Feb-12-2013A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University, Sweden, in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels' protective function...
Stem Cell Breakthrough Could Lead To New Bone Repair Therapies On Nanoscale Surfaces
Date: Feb-12-2013Scientists at the University of Southampton have created a new method to generate bone cells which could lead to revolutionary bone repair therapies for people with bone fractures or those who need hip replacement surgery due to osteoporosis and osteoarthritis. The research, carried out by Dr Emmajayne Kingham at the University of Southampton in collaboration with the University of Glasgow and published in the journal Small, cultured human embryonic stem cells on to the surface of plastic materials and assessed their ability to change...
Apogenix Receives FDA Orphan Drug Designation For Apocept(TM) To Treat Myelodysplastic Syndromes And Initiates Clinical Phase I Study
Date: Feb-12-2013Apogenix GmbH, a clinical stage biopharmaceutical company developing novel protein therapeutics for the treatment of cancer and inflammatory diseases, announced today that its lead product, Apocept(TM) (APG101), has been granted orphan drug designation from the US Food and Drug Administration (FDA) for the treatment of Myelodysplastic syndromes (MDS). MDS are clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis leading to blood cytopenias, especially anemia...
Shire Regenerative Medicine Initiates Phase 3 Study Of ABH001 For Patients With Epidermolysis Bullosa
Date: Feb-12-2013Shire plc (LSE: SHP, NASDAQ: SHPG), have announced the initiation of a Phase 3 study designed to evaluate the efficacy and safety of ABH001, its dermal substitute therapy, for the treatment of non-healing wounds in patients with Epidermolysis Bullosa (EB), a group of rare genetic skin disorders that begin to manifest at birth or early childhood and occur in approximately 19 per 1 million live births in the US. [i] "People affected by EB suffer skin blisters and almost constant, acute pain and scarring," said the study's Principal Investigator, H...
Simple Home Test Can Halve The Risk Of Stroke And Cut The Risk Of Death For Thousands Of Patients On Warfarin Therapy
Date: Feb-12-2013MPs, clinicians and patients are uniting to drive change for patients on long-term warfarin A simple self-monitoring test could reduce the risk of stroke by half in thousands of people who currently take warfarin to prevent blood clots...
Diffusion Abnormality Index Provides Potential Imaging Biomarker To Indicate Brain Tumor Response To Radiation Therapy
Date: Feb-12-2013Diffusion abnormality index (DAI) shows promise as an imaging biomarker to measure brain tumor response to radiation therapy, according to research presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North American (RSNA). The study included 20 patients who had brain metastases and were treated with whole brain radiotherapy. The total of 45 lesions among the patients was further categorized as 16 responsive, 18 stable and 11 progressive lesions...
SUVmax Provides Valuable Indicator Of Progression-Free Survival In Stage I Non-Small Cell Lung Cancer Patients
Date: Feb-12-2013SUVmax (Maximum Standardized Uptake Value) may be a significant and clinically independent marker to indicate progression-free survival in stage I non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy (SBRT), according to research presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North American (RSNA)...
Evaluating Evolutionary Rates Could Provide Insight Into Functions Of Uncharacterized Genes
Date: Feb-12-2013Genes that have roles in the same biological pathways change their rate of evolution in parallel, a finding that could be used to discover their functions, said a researcher at the University of Pittsburgh School of Medicine in the February issue of GENETICS. Humans have nearly 21,000 genes that make as many proteins, but the functions of most of those genes have not been fully determined, said lead investigator Nathan Clark, Ph.D., assistant professor of computational and systems biology at the Pitt School of Medicine...
Pitt/UPMC Team Describes Technology That Lets Spinal Cord-Injured Man Control Robot Arm With Thoughts
Date: Feb-12-2013Researchers at the University of Pittsburgh School of Medicine and UPMC describe in PLoS ONE how an electrode array sitting on top of the brain enabled a 30-year-old paralyzed man to control the movement of a character on a computer screen in three dimensions with just his thoughts. It also enabled him to move a robot arm to touch a friend's hand for the first time in the seven years since he was injured in a motorcycle accident...
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