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SARS-like Virus Infects Human, UK
Date: Feb-11-2013A novel coronavirus infection has been confirmed in a UK patient who had recently returned from Pakistan and the Middle East, the UK Health Protection Agency announced. Coronaviruses are causes of severe respiratory infections, such as SARS (Severe Acute Respiratory Syndrome) as well as the common cold. The HPA (Health Protection Agency) says the patient is in a Manchester hospital receiving intensive care treatment. This case brings the total number of cases confirmed worldwide to 10 (two of them diagnosed in the United Kingdom)...
Canker Sore Drug Lowers Weight In Mice Without Diet, Exercise
Date: Feb-11-2013An off-patent drug used to treat canker sores and asthma helped lower the weight of obese mice without diet or exercise. The drug, known as amlexanox, was also able to reverse their diabetes and fatty liver. Researchers at the University of Michigan's Life Sciences Institute analyzed the mice in the lab of Alan Saltiel, the Mary Sue Coleman director of the Life Sciences Institute. The findings are published in the journal Nature Medicine...
"Achilles' Heal" Found For Lymphoid Leukemia
Date: Feb-11-2013International Study Suggests Improved Treatment Alternative for Lymphoid Leukemia Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models. Reporting their results Feb. 11 in the journal Cancer Cell, the scientists said the targeted molecular therapy described in their study could have direct implications for current treatment of acute lymphoid leukemia (ALL) in people...
Mouse Model Of Clear Cell Sarcoma Improves Understanding Of Rare, Deadly Cancer
Date: Feb-11-2013May Speed Development of Drugs to Target Gene Mutation Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form. CCS arises in connective soft tissues, such as tendons, fat, blood vessels and muscle...
Infant Gut Microbiota Influenced By Caesarean Section And Breastfeeding Practices
Date: Feb-11-2013Practices may affect health in later life Method of birth (vaginal birth s. cesarean delivery) and feeding practices (breastfeeding v. formula-feeding) influence the development of gut bacteria in newborns and thus may affect lifelong health, according to a new study in CMAJ (Canadian Medical Association Journal). Bacteria in the gut play an important role in health, helping digest food, stimulating the development of the immune system, regulating bowels and protecting against infection...
Fear Factor: Study Shows Brain's Response To Scary Stimuli
Date: Feb-11-2013Driving through his hometown, a war veteran with post-traumatic stress disorder may see roadside debris and feel afraid, believing it to be a bomb. He's ignoring his safe, familiar surroundings and only focusing on the debris; yet, when it comes to the visual cortex, a recent study at the University of Florida suggests this is completely normal. The findings, published in the Journal of Neuroscience, show that even people who don't have anxiety disorders respond visually at the sight of something scary while ignoring signs that indicate safety...
Bringing A New Perspective To Infectious Disease
Date: Feb-11-2013Enlisted in the fight against HIV, MIT engineers and scientists contribute new technology, materials and computational studies. With the recent launch of MIT's Institute for Medical Engineering and Science, MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery. Studying infectious diseases has long been primarily the domain of biologists...
Doctors 'Reverse' Brain Bleed Procedure To Treat Critically Ill Stroke Patients
Date: Feb-11-2013Doctors at Southampton's teaching hospitals have reversed a procedure developed to stem bleeding in the brain to help them save the lives of seriously ill stroke patients. The innovation, which involves placing a thin wire into the groin and passing it up to the skull using high definition TV images, is based on a technique originally used as an alternative to surgery for patients with ruptured brain aneurysms - fluid-filled bulges which force blood vessels to tear...
Stem Cells Show Promise In Extending Transplanted Kidneys' Survival Time
Date: Feb-11-2013Can stem cells provide an answer to the perplexing question of how to ensure long-term survival of transplanted kidneys? The results of a new Phase 1 clinical trial say maybe so. Details of the trial, conducted by researchers at Leiden University Medical Center, The Netherlands, are published in the current issue of STEM CELLS Translational Medicine. Kidney transplants have long been the treatment of choice for many patients with end-stage renal disease, and the short-term results are excellent...
UNMC Study Suggests Vitamin D Could Reduce Lung Inflammation In Asthma, COPD
Date: Feb-11-2013In the first study of its kind, results of a University of Nebraska Medical Center research study suggest that vitamin D may be important for humans exposed to agricultural organic dust. In the study, researchers found a significant decrease in lung inflammation in mice exposed to hog barn dust that received high doses of vitamin D. "We found that the relatively high vitamin D treatment group had significantly decreased lung inflammation. The mice still got inflammation but didn't get it as bad," said Jill Poole, M.D...
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