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Tiny Genetic Patch Stops Deafness
Date: Feb-05-2013Researchers used a small genetic patch to partially restore hearing and balance in deaf mice with Usher syndrome, according to a new report published in Nature Medicine. The animal study, which is still in its early stages, could eventually develop into new treatments for Usher syndrome, a congenital hearing disorder which usually goes hand-in-hand with blindness as well. When the scientists injected the profoundly deaf mice with the genetic patch, they developed into partially hearing mice with no balance problems...
Exercise Reduces Risk of Dementia Later In Life
Date: Feb-05-2013People who exercise and have higher physical fitness levels during middle age have a significantly reduced risk of developing dementia later in life. The finding came from a new study conducted by Laura F. DeFina, MD, of The Cooper Institute in Dallas, and her team, and was published in the journal Annals of Internal Medicine. Similarly, a study published in Archives of Neurology indicated that people over the age of 90 who have poor physical performance are at increased risk of developing dementia...
MicroRNA Molecule May Serve As Biomarker, Target For Brain Metastases In Breast Cancer Patients
Date: Feb-05-2013MicroRNA molecule called miR-7 decreased in highly metastatic cancer stem-like cells. Researchers have identified two molecules that could potentially serve as biomarkers in predicting brain metastases in patients with breast cancer, according to data published in Cancer Research, a publication of the American Association for Cancer Research. Currently, most deaths from breast cancer are a result of metastatic disease...
Pharma Packaging And Labeling Conference, 26-27 February 2013, Philadelphia, USA
Date: Feb-05-2013Following thorough content-based research, the 2013 agenda has been based specifically around the key challenges experienced by packaging and labeling at a time of tough industry pressure...
Getting CPOE Adoption Right - Interview, National Healthcare CMO/CMIO Summit, 14-15 March 2013, Atlanta, Georgia
Date: Feb-05-2013The adoption of Computerized Physician Order Entry (CPOE) technologies has been slow in the US, although 2014 is the proposed start date for Stage 2 of the Meaningful Use Requirements. For effective implementation, "clinical leadership is critical," said Chris Snyder, Chief Medical Information Officer, Peninsula Regional Medical Center. The Center was one of the early adopters of CPOE eight years ago, and Snyder found the input from medical and support staff essential, he went on to say...
Sexual Encounters Outside Partnership Major Cause Of HIV In Sub-Saharan Africa
Date: Feb-05-2013One of the main reasons for the HIV epidemic in sub-Saharan Africa is the sheer number of heterosexual couples having intercourse with people outside their partnership. A study published in The Lancet indicates that current anti-HIV strategies which focus solely on couples in which one member is infected with HIV, might not be enough to decrease the prevalence of HIV in the region...
Scientists Weaken Superbugs By Interfering With Their Metabolism
Date: Feb-05-2013By interfering with their cellular metabolism, scientists in the US have found a way to weaken antibiotic-resistant bacteria, in this case E. coli, so that they are once again susceptible to existing antibiotics. The researchers, from Wyss Institute at Harvard University and Boston University, describe how they won this particular battle in the war against superbugs, with weapons like sophisticated computer modeling and biotechnology, in a paper published online in Nature Biotechnology in January...
Prostate Cancer Treatments Often Cause Side Effects
Date: Feb-05-2013Prostate Cancer Study Tracks Long-term Urinary, Sexual and Bowel Function Side Effects Following Therapy A new study comparing outcomes among prostate cancer patients treated with surgery versus radiotherapy found differences in urinary, bowel and sexual function after short-term follow-up, but those differences were no longer significant 15 years after initial treatment. The study, led by first author Matthew Resnick, M.D., instructor in Urologic Surgery, Vanderbilt University Medical Center, was published in the Jan. 31 issue of the New England Journal of Medicine. From Oct...
Scientists Find Way To Knockup Genes
Date: Feb-05-2013Italian scientists use molecular RNA Chaperones to increase protein production from individual genes. The technique is being hailed as a breakthrough in biotechnology that will transform cell science, accelerating the development of new medicines. One of the most innovative biotechnologies of the last decade has recently been developed. SINEUP allows scientists, for the first time, to target individual genes in cells to knockup, or increase, the amount of protein they make. The technique will improve Protein manufacture, analyse the function of genes and engineer improved cell function...
Stillbirth And Liver Problems: New Treatment Target On The Horizon
Date: Feb-05-2013Obstetric cholestasis (OC) is a liver condition that occurs during pregnancy in women. It affects about one in 140 pregnancies in the UK, and can result in stillbirth.1,2 Abnormally high levels of substances in the body linked with pregnancy hormones can contribute to the development of OC, by reducing the body's ability to remove bile from the liver. This results in a build up of toxic bile acids in the bloodstream, causing severe itching especially on the hands and feet, from around week 28 of pregnancy...
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