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How The Nuclear Envelope Affects Nuclear Architecture - And Gene Regulation
Date: Feb-05-2013In a project that began with the retinal cells of nocturnal animals and has led to fundamental insights into the organization of genomic DNA, LMU researchers show how the nuclear envelope affects nuclear architecture - and gene regulation. The double-stranded DNA molecules that make up the genetic material are wrapped around protein complexes to form compacted "chromatin". The active portion of the genome is less densely packed, and thus more easily accessible, than the inactive fraction, and is referred to as euchromatin...
Primary Care Physicians Generally Prefer Delivering Radiology Test Results To Patients Themselves
Date: Feb-05-2013According to a study in the February issue of the Journal of the American College of Radiology, primary care physicians prefer to deliver the results of radiology examinations themselves and feel medico-legally obligated by recommendations within radiology reports. The radiology report is the primary means of communication between the radiologist, the patient, and the patient care team and serves an important role in facilitating patient care, especially for primary care physicians in the outpatient setting. "There is considerable interest in improving radiology reporting practices...
Improved Understanding Of Link Between Dairy Intake And Bone Health
Date: Feb-05-2013A study by researchers at the Institute for Aging Research (IFAR) at Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS), has found that dairy intake - specifically milk and yogurt - is associated with higher bone mineral density (BMD) in the hip, but not the spine. Cream, on the other hand, may be associated with lower BMD overall. Published in the journal Archives of Osteoporosis, these findings suggest that not all dairy products are equally beneficial in promoting bone strength...
Drug Overdose From Prescription Opioids Reaches Epidemic Levels In NYC
Date: Feb-05-2013Fatality rate for white males is 3 times higher than for blacks; Deaths from prescription opioids like Oxycontin soared to 7 times the rate of 1990 The rate of drug overdose from prescription opioids increased seven-fold in New York City over a 16-year period and was concentrated especially among white residents of the city, according to latest research at Columbia University's Mailman School of Public Health. The study is one of the earliest and most comprehensive analyses of how the opioid epidemic has affected an urban area. The findings are published in Drug and Alcohol Dependence...
Antibodies To Treat Rabies From Genetically Modified Tobacco Plants
Date: Feb-05-2013Smoking tobacco might be bad for your health, but a genetically altered version of the plant might provide a relatively inexpensive cure for the deadly rabies virus. In a new research report appearing in The FASEB Journal, scientists produced a monoclonal antibody in transgenic tobacco plants that was shown to neutralize the rabies virus. This new antibody works by preventing the virus from attaching to nerve endings around the bite site and keeps the virus from traveling to the brain...
Similar Forms Of Epilepsy In Both Cats And Humans
Date: Feb-05-2013Epilepsy arises when the brain is temporarily swamped by uncoordinated signals from nerve cells. Research at the Vetmeduni Vienna has now uncovered a cause of a particular type of epilepsy in cats. Surprisingly, an incorrectly channelled immune response seems to be responsible for the condition, which closely resembles a form of epilepsy in humans. The work is published in the current issue of the Journal of Veterinary Internal Medicine. There is something sinister about epilepsy: the disease affects the very core of our being, our brain...
Mutations In ASXL3 Cause Problems Similar To Bohring-Opitz Syndrome
Date: Feb-05-2013Mutations which affect the gene ASXL3 cause a novel syndrome similar to Bohring-Opitz syndrome, finds a study published in BioMed Central's open access journal Genome Medicine. This molecular definition distinguishes these children from those with Bohring-Opitz, and other similar syndromes, and highlights a technique able to help define rare diseases...
Changing Bioelectric Signals A Key To Halting Tumor Growth
Date: Feb-05-2013Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower the incidence of cancerous cells by manipulating the electrical charge across cells' membranes. "The news here is that we've established a bioelectric basis for the early detection of cancer," says Brook Chernet, doctoral student and the first author of a newly published research paper co-authored with Michael Levin, Ph.D...
Cartilage Tympanoplasty In Pediatric Hearing Loss
Date: Feb-05-2013Cartilage tympanoplasty can be performed successfully in 95 percent of young children when appropriate conditions exist, according to a study in the February 2013 issue of Otolaryngology-Head and Neck Surgery. "Pediatric tympanoplasty is a frequently performed procedure with varying reported success rates ranging between 35 percent and 94 percent. In general, tympanic membrane repair success in children is often perceived as lagging behind what is typically achieved in adults having similar underlying risk factors," the authors write...
State Action On Affordable Care Act's 2014 Health Insurance Market Reforms:New Report
Date: Feb-05-2013Only 11 states and the District of Columbia have passed laws or issued regulations to implement the Affordable Care Act's major health insurance market reforms that go into effect in 2014, according to a new Commonwealth Fund report. Thirty-nine states have not yet taken action to implement these requirements, potentially limiting their ability to fully enforce the new reforms and ensure that consumers receive the full protections of the law...
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