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Human Cells Probed With High-Frequency Sound
Date: Feb-04-2013Sound waves are widely used in medical imaging, such as when doctors take an ultrasound of a developing fetus. Now scientists have developed a way to use sound to probe tissue on a much tinier scale. Researchers from the University of Bordeaux in France deployed high-frequency sound waves to test the stiffness and viscosity of the nuclei of individual human cells. The scientists predict that the probe could eventually help answer questions such as how cells adhere to medical implants and why healthy cells turn cancerous...
Identifying The Genes Responsible For Autism Disorders Is Critical For Diagnosis And Treatment
Date: Feb-04-2013Autism spectrum disorders affect nearly 1 in 88 children, with symptoms ranging from mild personality traits to severe intellectual disability and seizures. Understanding the altered genetic pathways is critical for diagnosis and treatment. New work to examine which genes are responsible for autism disorders were presented at the 57th Annual Meeting of the Biophysical Society (BPS), held Feb. 2-6, 2013, in Philadelphia, Pa. "Autism is the most inheritable of neurodevelopmental disorders," explains Rajini Rao of Johns Hopkins University in Baltimore, Md...
Interactions Between Two Molecules Thought To Play Critical Roles In Type II Diabetes And The Alzheimer's Disease
Date: Feb-04-2013A research team in Israel has devised a novel approach to identifying the molecular basis for designing a drug that might one day decrease the risk diabetes patients face of developing Alzheimer's disease. The team will present its work at the 57th Annual Meeting of the Biophysical Society (BPS), held Feb. 2-6, 2013, in Philadelphia, Pa. A recent study suggests that people who suffer from type 2 diabetes face twice the risk of developing Alzheimer's disease later in life compared to those who do not have diabetes...
Automated Device Created That Improves Understanding Of How Antibiotic Resistance Evolves At The Genetic Level
Date: Feb-04-2013With the discovery of antibiotics, medicine acquired power on a scale never before possible to protect health, save lives, and reduce suffering caused by certain bacteria. But the power of antibiotics is now under siege because some virulent infections no longer respond to antibiotic drugs. This antibiotic resistance is an urgent public health threat that a team of researchers from Sabanci University in Istanbul, Turkey, and Harvard Medical School and Harvard University in Cambridge, Mass., aim to stop...
New Approach To Delivering Therapeutics Through The Blood Brain Barrier Could Lead To Better Treatment Of Central Nervous System Disorders
Date: Feb-04-2013The treatment of central nervous system (CNS) diseases can be particularly challenging because many of the therapeutic agents such as recombinant proteins and gene medicines are not easily transported across the blood-brain barrier (BBB). Focused ultrasound can be used to "open the door" of the blood brain barrier...
Inflammatory Breast Cancer Treatment May Be Possible Using Quantum Dots To Deliver Vitamin D To Tumors
Date: Feb-04-2013The shortened daylight of a Maine winter may make for long, dark nights - but it has shone a light on a novel experimental approach to fighting inflammatory breast cancer (IBC), an especially deadly form of breast cancer. The new approach enlists the active form of Vitamin D3, called calcitriol, which is delivered therapeutically by quantum dots. Quantum dots are an engineered light-emitting nanoscale delivery vehicle...
Method Of Temperature Imaging Looks At Cellular Functions, Clarifies Pathogenesis Of Diseases Like Cancer
Date: Feb-04-2013A research team in Japan exploring the functions of messenger ribonucleic acid (mRNA) - a molecule that encodes the chemical blueprint for protein synthesis - has discovered a way to take a close look at the temperature distribution inside living cells. This discovery may lead to a better understanding of diseases, such as cancer, which generate extraordinary intracellular heat. This breakthrough is the first time anyone has been able to show the actual temperature distribution inside living cells...
Personalized Medicine Eliminates Need For Drug In 2 Children
Date: Feb-04-2013Using genome-wide analysis, investigators at the Sainte-Justine University Hospital Research Center and the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years. Over a lifespan, the adjustment in treatment represents an approximate saving of $10,000 in drug and test costs per patient. Moreover, the less invasive treatment regime can potentially reduce the lifetime risk of hypertension in the patients...
A Positive Family Climate In Adolescence Is Linked To Marriage Quality In Adulthood
Date: Feb-04-2013Experiencing a positive family climate as a teenager may be connected to your relationships later in life, according to new research published in Psychological Science, a journal of the Association for Psychological Science. While research has demonstrated long-term effects of aggression and divorce across generations, the impact of a positive family climate has received less attention...
Time Spent Watching Television Is Not Associated With Death Among Breast Cancer Survivors
Date: Feb-04-2013Spending a lot of time watching television after breast cancer diagnosis is not linked to death in these breast cancer survivors. It appears that after accounting for self-reported physical activity levels after diagnosis, sedentary behavior was not an independent risk factor for death. These findings by Stephanie George, from the National Cancer Institute, and her colleagues, are published online in Springer's Journal of Cancer Survivorship...
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