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Men Taking Long-Acting Chronic Pain Meds 5 Times More Likely To Have Low Testosterone Levels
Date: Feb-04-2013Low testosterone levels occur five times more often among men who take long-acting instead of short-acting opioids for chronic pain, according to a new Kaiser Permanente study published in The Clinical Journal of Pain. While it has been known that opioids cause low testosterone in men, this study is the first to show a significant difference in risk between short-acting (immediate release) and long-acting opioids...
Altruism In The Face Of Disasters: Older Children Likely To Be More Giving, Younger Children To Be More Selfish
Date: Feb-04-2013A natural disaster can bring out the best in older children, prompting 9-year-olds to be more willing to share, while 6-year-olds become more selfish. Researchers at the University of Toronto, the University of Chicago, and Liaoning Normal University made this finding in a rare natural experiment in China around the time of a horrific earthquake. A crucial difference between the two age groups emerged one month after the disaster. The 6-year-olds' willingness to share in a test measuring altruism dropped by a third, while among 9-year-olds, willingness to give to others nearly tripled...
Researchers Identify New Drug Target For Multiple Sclerosis And Alzheimer's Disease
Date: Feb-04-2013Researchers at Boston University School of Medicine (BUSM) led by Carmela Abraham, PhD, professor of biochemistry, along with Cidi Chen, PhD, and other collaborators, report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings, which appear online in Journal of Neuroscience, may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD), in which white matter abnormalities are also common but have been largely ignored...
Hope For An Injectable Antidote Suitable For Treatment Of Cyanide Victims In A Mass Casualty Setting
Date: Feb-04-2013In an advance toward closing a major gap in defenses against terrorist attacks and other mass casualty events, scientists are reporting discovery of a promising substance that could be the basis for development of a better antidote for cyanide poisoning. Their report, which describes a potential antidote that could be self-administered, much like the medication delivered by allergy injection pens, appears in ACS' Journal of Medicinal Chemistry. Steven E. Patterson, Ph.D...
A New Genre Of 'Intelligent' Micro- And Nanomotors
Date: Feb-04-2013Enzymes, workhorse molecules of life that underpin almost every biological process, may have a new role as "intelligent" micro- and nanomotors with applications in medicine, engineering and other fields. That's the topic of a report in the Journal of the American Chemical Society, showing that single molecules of common enzymes can generate enough force to cause movement in specific directions. Peter J. Butler, Ayusman Sen and colleagues point out that enzymes - proteins that jump-start chemical reactions - are the basis of natural biological motors essential to life...
The Significance Of Second Trimester Markers For Down's Syndrome
Date: Feb-04-2013A new analysis has found that some second trimester markers for Down's syndrome that are detected by ultrasound are more telling than others. Published early online in Ultrasound in Obstetrics & Gynecology, the study's results will help adjust pregnant women's risks for having a child with the condition. Screening for Down's syndrome is offered to all pregnant women, who start out with a background risk based on their age...
Medical Units Improved To Reduce Nursing Fatigue, Cut Costs
Date: Feb-04-2013In hospitals, poor floor design, storage closet clutter and crowded corridors can contribute to nurse and medical staff fatigue. These distractions can hurt patient care quality and result in higher medical costs. Now, a new Cornell University study offers a spatial solution. Rana Zadeh, Cornell assistant professor of design and environmental analysis in the College of Human Ecology, analyzed the floor plans and work patterns within five medical-surgical units at U.S. hospitals and found numerous opportunities to boost nurses' efficiency through better design...
Malala Undergoes Two Surgeries, Recovering Well
Date: Feb-04-2013Malala Yousafzai, 15, the Pakistani schoolgirl who received a bullet wound in the head, has undergone surgery at Queen Elizabeth Hospital, Birmingham, England. A hospital spokeswoman said that the medical team was "very pleased" with her progress after the operation, which lasted five hours. At that time the patient was said to be awake and talking to staff and family members. Malala had been shot in the head at point blank range by the Taliban on October 9th, 2012, in an assassination attempt while on her way home on a school bus in Pakistan...
Two-Step Immunotherapy Attacks Advanced Ovarian Cancer, Penn Medicine Researchers Report
Date: Feb-04-2013Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine show that a two-step personalized immunotherapy treatment - a dendritic cell vaccine using patients' own tumor followed by adoptive T cell therapy - triggers anti-tumor immune responses in these type of patients. Four of the six patients treated in the trial responded to the therapy, the investigators report this month in OncoImmunology...
Just 11 Percent Of Adults, 5 Percent Of Children Participate In Medical Research
Date: Feb-04-2013Medical research is vital to the advancement of health care, but many medical research studies have too few people who participate. A new study from the University of Michigan takes an in-depth look at public participation in medical research across the United States. Through a unique, nationally representative survey of 2,150 households in 2011, University of Michigan researchers found that only 11% of adults and 5% of children had ever participated in medical research. The study was published in January in Clinical and Translational Science...
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