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Boosting 'Slow Wave' Sleep Could Restore Memory As We Age
Date: Jan-28-2013The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory...
Skin Cells From Patients With Inherited Heart Condition Recreate The Adult-Onset Disease
Date: Jan-28-2013Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by 2012 Nobel Prize winner Shinya Yamanaka, M.D., Ph.D., helps solve this problem. With this technology, researchers can generate heart muscle cells from a patient's own skin cells...
The Mechanism Of Epigenetic Reprogramming Revealed
Date: Jan-28-2013New research reveals a potential way for how parents' experiences could be passed to their offspring's genes. The research was published in the journal Science. Epigenetics is a system that turns our genes on and off. The process works by chemical tags, known as epigenetic marks, attaching to DNA and telling a cell to either use or ignore a particular gene. The most common epigenetic mark is a methyl group. When these groups fasten to DNA through a process called methylation they block the attachment of proteins which normally turn the genes on. As a result, the gene is turned off...
African-American Women Who Suffered Abuse During Childhood At Increased Risk For Uterine Fibroids
Date: Jan-28-2013According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared with women who had no such abuse history. The association was strongest for women who experienced sexual abuse. The study, which is published online in the American Journal of Obstetrics and Gynecology, was led by Lauren A. Wise, ScD, senior epidemiologist at SEC and associate professor of epidemiology at the Boston University School of Public Health...
Training Yourself To Have More Willpower
Date: Jan-28-2013You can train your body, your mind ... and your willpower. That's according to a new study by researchers at The Miriam Hospital's Weight Control and Diabetes Research Center, who say that with a little practice, it may be possible to strengthen and improve your self-control - and lose more weight. The Miriam research team found that individuals with more willpower - or self-control - lost more weight, were more physically active, consumed fewer calories from fat and had better attendance at weight loss group meetings...
Type Of Anesthetic Used, Number Of Exposures And Age Contribute To Risk Of Inflammation, Cognitive Deficits
Date: Jan-28-2013Several studies have found evidence that children who undergo repeated surgical operations with general anesthesia before the age of 4 may be at an increased risk for learning disabilities. In the March issue of Anesthesiology, Massachusetts General Hospital (MGH) researchers report an animal study indicating that several factors - age, the specific anesthetic agent used and the number of doses - combine to induce impairments in learning and memory accompanied by the inflammation of brain tissue...
Prototype Drug Stabs Membranes To Kill Microbes That Cause Pneumonia, Sepsis, Other Infections
Date: Jan-28-2013An engineered peptide provides a new prototype for killing an entire category of resistant bacteria by shredding and dissolving their double-layered membranes, which are thought to protect those microbes from antibiotics. The synthetic peptide was effective in lab experiments against antibiotic-resistant Gram-negative bacteria, which cause a variety of difficult-to-treat, potentially lethal infections such as pneumonia and sepsis...
Epithelial Cell Cooperation Analyzed As Cells 'Flock' To Heal Wounds
Date: Jan-28-2013Like flocks of birds, cells coordinate their motions as they race to cover and ultimately heal wounds to the skin. How that happens is a little less of a mystery today. Researchers once thought only the cells at the edge of a growing patch of wounded skin were actively moving while dividing cells passively filled in the middle. But that's only part of the picture. Rice University physicist Herbert Levine and his colleagues have discovered that the process works much more efficiently if highly activated cells in every part of the patch exert force as they pull their neighbors along...
Neuroscientists Create Fiber-Optic Method Of Arresting Epileptic Seizures
Date: Jan-28-2013UC Irvine neuroscientists have developed a way to stop epileptic seizures with fiber-optic light signals, heralding a novel opportunity to treat the most severe manifestations of the brain disorder. Using a mouse model of temporal lobe epilepsy, Ivan Soltesz, Chancellor's Professor and chair of anatomy & neurobiology, and colleagues created an EEG-based computer system that activates hair-thin optical strands implanted in the brain when it detects a real-time seizure...
No Significant Cancer Risk For Patients From Lupus Drugs
Date: Jan-28-2013People who take immunosuppressive drugs to treat lupus do not necessarily increase their cancer risk according to new research led by scientists at the Research Institute of the McGill University Health Centre (RI-MUHC). This landmark study, which was published in Annals of the Rheumatic Diseases this month, addresses long-standing fears of a link between lupus medication and cancer...
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