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Regulator Of Skin Aging
Date: Jan-23-2013Despite progress in regenerative medicine, with age, the skin loses its properties in an irreversible manner. The ATIP-Avenir team "Epidermal homeostasis and tumorigenesis" directed by Chloe Feral, an Inserm researcher at the French Cancer and Aging Research Institute (Inserm/CNRS/Universite Sophia Antipolis), has just defined the cellular and molecular mechanisms involved in maintaining skin cells and skin healing in advanced years...
No Adverse Reactions To Single Dose Influenza Vaccine In Children Allergic To Egg
Date: Jan-23-2013Egg allergic children, including those with a history of anaphylaxis to egg, can safely receive a single dose of the seasonal influenza vaccine, according to a new study from the University of Michigan. Historically, the CDC recommended that the seasonal influenza vaccine not be administered to egg allergic children. Recent research conducted at the University of Michigan, and elsewhere, helped modify this recommendation in 2011 so that caution was warranted for only those with severe egg allergy...
High Probability of Readmission After Hospitalization
Date: Jan-23-2013An estimated 2 in every 10 people who are hospitalized have to receive acute care 30 days following discharge, with close to 40 percent of such cases resulting in emergency department visits. This finding comes from a recent study published in the latest issue of JAMA. According to the background information in the article, the readmissions are often related to the first hospitalization and can be extremely costly...
Earlier Diagnosis Of Parkinson's Disease Likely Using Blood-Based Biomarkers
Date: Jan-23-2013Parkinson's disease (PD) is a progressive neurological condition. At present, it is usually diagnosed only when motor features are present. Hence, there is a need to develop objective and measurable biomarkers to improve PD diagnostics during its earlier stage, prior to its motor onset. In this pilot study, researchers identified and tested the first blood-based circulating microRNA (miRNA) biomarkers for PD. Their results are published in the latest issue of Journal of Parkinson's Disease...
Hairpin Strategy Employed By Measles Virus Foils Immune System
Date: Jan-23-2013The innate immune system detects invasive pathogens and activates defense mechanisms to eliminate them. Pathogens, however, employ a variety of tricks to block this process. A new study shows how the measles virus thwarts the system, by means of a simple hairpin-like structure. The innate immune system is the body's first line of defense against invasive pathogens and noxious chemicals. Essentially the system consists of an array of receptors that recognize particular molecular conformations which are characteristic of pathogenic organisms and viruses...
Evolutionary Explanations For Why We Get Cancer
Date: Jan-23-2013Over 500 billion cells in our bodies will be replaced daily, yet natural selection has enabled us to develop defenses against the cellular mutations which could cause cancer. It is this relationship between evolution and the body's fight against cancer which is explored in a new special issue of the Open Access journal Evolutionary Applications. "Cancer is far from a single well-defined disease which we can identify and eradicate," said Dr Athena Aktipis, Director, Human and Social Evolution, Center for Evolution and Cancer at the University of California, San Francisco...
Marie Curie Project: "European Training Network For Excellence In Molecular Imaging In Diabetes"
Date: Jan-23-2013A new imaging method for the study of insulin-producing cells in diabetes among other uses is now being presented by a group of researchers at Umeå University in Sweden in the form of a video in the biomedical video journal, The Journal of Visualized Experiments. The developed techniques have contributed to the reasons why the research team recently received a SEK 4.3 million grant from the EU in a Marie Curie program to link together leading research teams in Europe in the field of diabetes imaging...
The Good, The Bad - And The Ugly Cholesterol That Causes Heart Disease
Date: Jan-23-2013The risk of ischaemic heart disease - a disease affecting some 150,000 Danes - is three times higher in persons with high levels of the so-called 'ugly' cholesterol. This is the finding of a new study of 73,000 Danes, which is shedding light on a long debate on this topic. The results have just been published in the Journal of the American College of Cardiology. Most Danes are aware that high cholesterol is life-threatening. But very few know which type of cholesterol is the most frequent killer...
HIV Infection Resisted By Immune Cells Engineered In Lab
Date: Jan-23-2013Researchers at the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS. A new study describes the use of a kind of molecular scissors to cut and paste a series of HIV-resistant genes into T cells, specialized immune cells targeted by the AIDS virus. The genome editing was made in a gene that the virus uses to gain entry into the cell...
Eczema Linked To Gut Bacteria In Kids
Date: Jan-23-2013Kids who have eczema have a more diverse set of bacteria in their guts than kids who do not have the condition. The finding came from new research conducted by a team of experts from the University of Turku, Finland, and was published in BioMed Central's open access journal BMC Microbiology. The scientists discovered that the types of bacteria existing in the guts of the children with eczema were more typical of adult gut microbes than for infants without eczema...
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