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Co-Morbidities Associated With Childhood Obesity

Date: Jan-15-2013
While a great deal of research on childhood obesity has spotlighted the long-term health problems that emerge in adulthood, a new UCLA study focuses on the condition's immediate consequences and shows that obese youngsters are at far greater risk than had been supposed. Compared to kids who are not overweight, obese children are at nearly twice the risk of having three or more reported medical, mental or developmental conditions, the UCLA researchers found. Overweight children had a 1.3 times higher risk...

Effective Interventions For Reducing Pedestrian Injury Improves Child Safety In New York City

Date: Jan-15-2013
The national Safe Routes to School (SRTS) program was funded by Congress in 2005 in an effort to create safe environments for American children to walk or bike to school. Has the program been effective? In New York City, most definitely, according to a new study conducted at Columbia University's Mailman School of Public Health that evaluated the program here. Researchers found that the annual rate of injury to school-age pedestrians ages 5-19 fell 44% during the peak times for walking to school, in neighborhoods where the program was implemented...

News From The Annals Of Internal Medicine: Jan. 15, 2013

Date: Jan-15-2013
1. Selective D-Dimer Testing for Suspected Deep Vein Thrombosis Safe and More Efficient than Testing Everyone D-dimer testing based on clinical pretest probability for deep vein thrombosis (DVT) is safe and reduces diagnostic testing compared with testing all patients...

News From The January/February 2013 Annals Of Family Medicine

Date: Jan-15-2013
Electronic Health Record Adoption by Family Physicians Doubles, Projected to Reach 80 Percent by 2013 Adoption of electronic health records by family physicians has doubled since 2005, reaching 68 percent nationally in 2011. According to analysis of two independent data sets, researchers found family physicians are adopting electronic health records at a higher rate than other office-based physicians and are likely to exceed 80 percent penetration by 2013 if the current trend continues...

Distinct Circuit Dysfunctions May Contribute To Different Features Of Emotion Dysregulation In Bipolar Disorder

Date: Jan-15-2013
Bipolar disorder is a severe mood disorder characterized by unpredictable and dramatic mood swings between the highs of mania and lows of depression. These mood episodes occur among periods of 'normal mood', termed euthymia. Prior research has clearly shown that brain emotion circuitry is dysregulated in individuals diagnosed with bipolar disorder. It is thought that these disturbances impair one's ability to control emotion and contribute to mood episodes...

Patients' Threat Perception Following Heart Attack Impacts Depression

Date: Jan-15-2013
"Survivors of heart attacks are three times more likely to develop depression during the first six months after their heart attack, than people with no heart disease. If left untreated this contributes to a worse prognosis, for instance further cardiac events and possibly death. The causes for this high prevalence of depression after heart attacks are still unclear," said Prof. Claus Vögele, Professor of Clinical and Health Psychology at the University of Luxembourg and lead author of the publication entitled "Cardiac Threat Appraisal and Depression after First Myocardial Infarction"...

Surviving Hemorrhage Less Likely If Patients Smoke, Have High Blood Pressure, High Cholesterol

Date: Jan-15-2013
"It is particularly important for subarachnoid haemorrhage survivors to refrain from smoking and to take care of their blood pressure and cholesterol levels; apart from age, these are the primary factors behind the increased risk of mortality," explains neurosurgeon Miikka Korja from the HUCH's Neurosurgery Department together with professor Jaakko Kaprio from the University of Helsinki's Hjelt Institute...

Debating Protein Recognition And Disorder

Date: Jan-15-2013
Two articles published in F1000 Biology Reports debate whether protein recognition can occur in the absence of stable structure. The extent to which three-dimensional structure is required for protein recognition and function is an area of vigorous debate with clear implications for protein engineering. Two differing viewpoints have been put forward in two articles published in F1000 Biology Reports. In structuring their arguments, the authors were encouraged to consider the opposing viewpoint, examine the points put forward and critique them in their own articles...

Research Likely To Improve Drugs Used To Fight Cancer, Diabetes And Other Diseases

Date: Jan-15-2013
Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly policing the streets, making repairs, building new structures and delivering important cargo throughout the bustling organic society. For everything to work properly there must be something to organize and direct the various workers. Enter protein kinases...

IPSCs Define Optimal Treatment For Managing Life-Threatening Arrhythmias

Date: Jan-15-2013
Researchers used induced pluripotent stem cells (iPSCs) derived from a young patient with Long QT syndrome (LQTS), a congenital heart disorder, to determine a course of treatment that helped manage the patient's life-threatening arrhythmias. The results, which appear in The Journal of General Physiology, could lead to improved treatments for LQTS and other channelopathies, diseases caused by disturbed ion channel function...