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Anxious Parents Create Anxious Children
Date: Nov-02-2012Parents with social anxiety disorder are more inclined than parents with other forms of anxiety disorders to behave in ways that put their kids at a high risk for developing stress of their own, suggests a new study by researchers at John Hopkins Children's Center. Earlier studies have shown connections between parental anxiety and anxiety in children, but nobody really knew whether people with certain anxiety disorders took part more frequently in anxiety-provoking behaviors. This new report, published in the journal Child Psychiatry and Human Development, suggests they do...
New Paradigms To Fund Biotech Conference, 8-9 January 2013, San Francisco
Date: Nov-02-2012The Conference Forum has announced that Dennis Purcell, Senior Managing Partner of Aisling Capital, will host a series of interviews with some of the top, unique life science deals of 2012 on January 8th, 2013 at the 3rd Annual New Paradigms event in San Francisco...
News From The Journal Of Clinical Investigation: Nov. 1, 2012
Date: Nov-02-2012Congenital diarrheal disorder linked to a mutation in DGAT1 Congenital diarrheal disorders (CDD) are a group of rare intestinal diseases that are caused by genetic mutations. In a study published in the Journal of Clinical Investigation, Robert Farese and colleagues at the University of California, San Francisco, identified a family with two of three children affected by CDD. The affected children both carried a rare mutation in the DGAT1 gene. DGAT1 mediates the formation of triglycerides and is being assessed as a therapeutic target in the treatment of obesity...
"Rebooting" MS Drug Succeeds In Trials
Date: Nov-02-2012Two phase 3 trials of a drug for treating multiple sclerosis (MS) that "reboots" the immune system showed it to be effective in patients who had not responded to first-line therapy: it reduced risk of disability and brain shrinkage. Reporting in the 1 November issue of The Lancet, the researchers describe how alemtuzumab (known commercially as Lemtrada), previously used to treat a type of leukaemia, was able to help people with early MS who relapsed on previous treatments as well as patients who had not yet received any treatment...
Predicting Tamoxifen Resistance In Breast Cancer Treatment
Date: Nov-02-2012Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen. Tamoxifen - used alongside traditional chemotherapy and radiotherapy - blocks the female hormone oestrogen that, in certain breast cancers, is required by the tumour to grow; it has been shown to improve cancer survival rates by up to one third. However, about one third of patients with the appropriate type of breast cancer - known as oestrogen receptor positive breast cancer - do not respond to tamoxifen or develop resistance to the drug...
Herpes Viruses And Co-Infection
Date: Nov-02-2012The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue...
New Tick Disease In Switzerland
Date: Nov-02-2012Until now, we knew that ticks primarily transmit two pathogens to humans in Switzerland: the bacterium Borrelia burgdorferi - which causes borreliosis - and the early-summer-meningoencephalitis virus, which can cause cerebral inflammation. Now, microbiologists from the University of Zurich confirm the existence of another tick disease in Switzerland - neoehrlichiosis. The pathogenic bacteria Candidatus Neoehrlichia mikurensis was first discovered in ticks and rodents in Europe and Asia in 1999...
Medicare Barrier To Hospice Increases Hospitalization
Date: Nov-02-2012A Medicare rule that blocks thousands of nursing home residents from receiving simultaneous reimbursement for hospice and skilled nursing facility (SNF) care at the end of life may result in those residents receiving more aggressive treatment and hospitalization, according a new analysis...
Automated Calls Advising Self-Care Help Patients In Under-Developed Countries Manage Hypertension
Date: Nov-02-2012Hypertension is one of the greatest epidemics threatening the health of people in low and middle-income countries. For patients struggling with high blood pressure in countries with limited access to health care, the key to improving health may be as simple as a phone call. New University of Michigan research evaluated the impact of automated calls from a U.S.-based server to the mobile phones of patients with hypertension (high blood pressure) in Honduras and Mexico. The program was designed to be a low-cost way of providing long distance checkups and self-management education...
New Micropumps For Hand-Held Medical Labs Produce Pressures 500 Times Higher Than Car Tyre
Date: Nov-02-2012In an advance toward analyzing blood and urine instantly at a patient's bedside instead of waiting for results from a central laboratory, scientists are reporting development of a new micropump capable of producing pressures almost 500 times higher than the pressure in a car tyre. Described in ACS' journal Analytical Chemistry, the pumps are for futuristic "labs-on-a-chip," which reduce entire laboratories to the size of a postage stamp...
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