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Antisense Technology That Exploits Gene Splicing Mechanism Used To Kill Cancer Cells
Date: Nov-02-2012Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. To do this they need to speed up their metabolism. CSHL Professor Adrian Krainer and his team have found a way to target the cancer cell metabolic process and in the process specifically kill cancer cells. Nearly 90 years ago the German chemist and Nobel laureate Otto Warburg proposed that cancer's prime cause was a change in cell metabolism - i.e...
Human-Animal Interaction Transformed By Virtual Reality 'Beaming' Technology
Date: Nov-02-2012Using cutting-edge virtual reality technology, researchers have 'beamed' a person into a rat facility allowing the rat and human to interact with each other on the same scale. Published in PLOS ONE, the research enables the rat to interact with a rat-sized robot controlled by a human participant in a different location. At the same time, the human participant (who is in a virtual environment) interacts with a human-sized avatar that is controlled by the movements of the distant rat. The authors hope the new technology will be used to study animal behaviour in a completely new way...
Confirmation Of Nitisinone Efficacy For Life-Threatening Liver Disease
Date: Nov-02-2012After 5 years of treatment, no trace of the disease can be detected in the liver of newborns who were treated starting from the first month of life A consortium of Quebec researchers coordinated by the Medical Genetics Service of the Sainte-Justine UHC has just published the findings of a 25-year study on the treatment of tyrosinemia, a life-threatening liver disease of genetic origin, which is screened at birth in the province of Quebec, where it is much more frequent than anywhere else in the world...
For Best Outcomes In Stroke, Near-Complete Blood Flow Restoration Critical
Date: Nov-02-2012Two Rhode Island Hospital researchers recently found that restoring near-complete blood flow to the brain is necessary to restore or preserve neurological function following stroke. Seems like a no-brainer, right? Yet until their research was complete, many physicians and researchers believed that partial blood-flow restoration was good enough. Not anymore. The study by Mahesh Jayaraman, M.D., director of interventional neuroradiology, and Brian Silver, M.D...
Continued Controversy Over Flame Retardants In Millions Of Sofas, Chairs And Other Products
Date: Nov-02-2012Flame retardants in the polyurethane foam of millions of upholstered sofas, overstuffed chairs and other products have ignited a heated debate over safety, efficacy and fire-safety standards - and a search for alternative materials. That's the topic of a cover story package in the current edition of Chemical & Engineering News (C&EN), the weekly newsmagazine of ACS, the world's largest scientific society...
Key To Preventing Lung Disease In Babies Could Be Microscopic Packets Of Stem Cell Factors
Date: Nov-02-2012Researchers at Boston Children's Hospital have found that microscopic particles containing proteins and nucleic acids called exosomes could potentially protect the fragile lungs of premature babies from serious lung diseases and chronic lung injury caused by inflammation. The findings explain earlier research suggesting that while transplanting a kind of stem cell called mesenchymal stem cells (MSCs) could help reduce lung injury and prevent inflammation in a mouse model, the fluid in which the cells were grown was more effective than the cells themselves...
Definition Of Remission From Depression: Are Clinicians And Patients On The Same Wavelength?
Date: Nov-02-2012Rhode Island Hospital researcher Mark Zimmerman, M.D., director of outpatient psychiatry, has found that patients suffering from major depressive disorder (MDD) define remission from depression differently than clinicians. While many psychiatrists and clinicians view remission from a symptom-based standpoint, the study found that patients put much more emphasis on life satisfaction and sense of well-being than on actual symptoms. The paper is published online in advance of print in the Journal of Psychiatric Research...
In Several Childhood Psychiatric Disorders, A Single Protein Targeted As The Root Biological Cause
Date: Nov-02-2012A new research discovery has the potential to revolutionize the biological understanding of some childhood psychiatric disorders. Specifically, scientists have found that when a single protein involved in brain development, called "SRGAP3," is malformed, it causes problems in the brain functioning of mice that cause symptoms that are similar to some mental health and neurological disorders in children. Because this protein has similar functions in humans, it may represent a "missing link" for several disorders that are part of an illness spectrum...
Gastrointestinal Cancers Likely Reduced By Consumption Of Green Tea
Date: Nov-02-2012Women who drink green tea may lower their risk of developing some digestive system cancers, especially cancers of the stomach/esophagus and colorectum, according to a study led by researchers from Vanderbilt-Ingram Cancer Center. The study by lead author Sarah Nechuta, Ph.D., MPH, assistant professor of Medicine, was published online in advance of the Nov. 1 edition of the American Journal of Clinical Nutrition. Wei Zheng, M.D., Ph.D...
Do Retail Clinics Disrupt Doctor-Patient Relationships?
Date: Nov-02-2012A new RAND Corporation study examining the impact of retail medical clinics on the receipt of primary medical care finds mixed evidence about whether the clinics may disrupt doctor-patient relationships. The study found that people who visit retail medical clinics are less likely to return to a primary care physician for future illnesses and have less continuity of care. However, there was no evidence retail medical clinics disrupted preventive medical care or management of diabetes, two important measures of quality of primary care...
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