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'ACT TIL' Approach Studied For The Treatment Of Metastatic Melanoma
Date: Oct-20-2012Researchers at Moffitt Cancer Center have carried out a clinical trial in which patients with metastatic melanoma were given chemotherapy and an immunotherapy of adoptive cell transfer (ACT) with tumor infiltrating lymphocytes (TIL). Tumor tissues were surgically removed from patients, minced and grown in culture. The treatment combined chemotherapy, then ACT with TIL, followed by interleukin-2 (IL-2). The combination therapy drew a high response rate from some patients. The study appears in the October issue of the Journal of Immunotherapy...
Virus Behavior Insight Offers Hope For New Drugs
Date: Oct-19-2012An important stage in the life-cycle of viruses such as the common cold and polio has been discovered by experts at the University of Leeds. This breakthrough may pave the way for new methods of battling viral diseases. According to the study, published in the Proceedings of the National Academy of Sciences (PNAS), the researchers were the first to notice, at anatomic level, how the genome that creates the core of a single-strand RNA virus particle accumulates in its outer shell of proteins...
New Drug Combination Can Prevent Lymphoma Relapse
Date: Oct-19-2012A new drug used in unison with radiotherapy is four times more likely to result in long-term survival for lymphoma patients, than just radiotherapy alone, researchers from the University of Manchester have shown. This new study, published in Blood, shows the chemical R848 can be used to prepare the immune system to battle cancer. In the fight against lymphoma, relapse is a common scenario, and new treatments are desperately needed. These authors hope this new drug will trigger the cancer-fighting properties of the body's own immune system...
Face Transplant Patient Exceeding All Expectations
Date: Oct-19-2012Richard Lee Norris, 37, who lost most of his face in a gun accident in 1997, and underwent the most extensive full face transplant ever seven months ago, is "exceeding all expectations", his doctors announced this week. Richard Lee Norris had suffered a horrific gun accident in 1997 which claimed his lips, part of his jaw, and his nose. After literally having his face blown off, he managed his life as best he could for 15 years, wearing a mask and living as a recluse until he was selected for surgery. In March 2012, at the R...
Why Skipping Breakfast Increases Appeal Of High Calorie Foods
Date: Oct-19-2012Scientists presenting a new study at a conference this week suggest the reason skipping breakfast makes high calorie food more appealing later in the day is because our brain circuits may be primed toward seeking it when fasting. Lead author of the study, Tony Goldstone of Imperial College London in the UK, and colleagues, compared people's MRI brain scans and their eating patterns, both after breakfast and when they skipped it. They presented their findings at Neuroscience 2012 in New Orleans on Wednesday...
'Capture The Fracture' Report Calls For Implementation Of Coordinator-Based Systems Of Post-Fracture Care
Date: Oct-19-2012A newly released IOF report for World Osteoporosis Day, 'Capture the Fracture - A global campaign to break the fragility fracture cycle', clearly outlines the care gap which is leaving millions of fracture patients undiagnosed and without treatment for osteoporosis or assessment for falls risk. IOF CEO Judy Stenmark stated, "An adult who has experienced a first fragility fracture - often at the wrist or vertebrae - is at double the risk of having a fracture as compared to someone who hasn't fractured...
Researchers Clarify Process Controlling Night Vision
Date: Oct-19-2012On the road at night or on a tennis court at dusk, the eye can be deceived. Vision is not as sharp as in the light of day, and detecting a bicyclist on the road or a careening tennis ball can be tough. New research reveals the key chemical process that corrects for potential visual errors in low-light conditions. Understanding this fundamental step could lead to new treatments for visual deficits, or might one day boost normal night vision to new levels...
Social Judgment Impaired In Children With Autism: They Can Identify Misbehavior But Have Trouble Putting It In Words
Date: Oct-19-2012Children with autism have difficulty identifying inappropriate social behavior, and even when successful, they are often unable to justify why the behavior seemed inappropriate. New brain imaging studies show that children with autism may recognize socially inappropriate behavior, but have difficulty using spoken language to explain why the behavior is considered inappropriate, according to research published Oct. 17 in the open access journal PLOS ONE by Elizabeth Carter from Carnegie Mellon University and colleagues...
Bladder Cancer Mortality Increased By Depression And Shortened Telomeres
Date: Oct-19-2012The combination of shortened telomeres, a biological marker of aging associated with cancer development, and elevated depression significantly impacted bladder cancer mortality, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 16-19, 2012. "We found that patients with bladder cancer with shorter telomeres and high levels of depression symptoms have a threefold increased risk for mortality," said Meng Chen, Ph.D., an epidemiologist at The University of Texas MD Anderson Cancer Center in Houston...
A Systematic Method For Recording Patients' Physical Activity Into Their Electronic Health Records
Date: Oct-19-2012Kaiser Permanente has created a new electronic Exercise Vital Sign initiative to systematically record patients' physical activity in their electronic health records. The new feature is successfully compiling accurate and valuable information that can help clinicians better treat and counsel patients about their lifestyles, according to a Kaiser Permanente study published in the journal Medicine & Science in Sports & Exercise...
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