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Multi-Tasking Clot-Busting Enzymes
Date: Oct-08-2012The body's blood clot-busting enzymes are much busier than previously imagined, with new research showing that they also dispose of every cell that dies prematurely from disease or trauma. In research published in Cell Reports, scientists from Monash University have demonstrated for the first time the enzyme t-PA, which plays a vital role in the removal of blood clots, is also a major player in the removal of necrotic, or dead, cells. Necrosis occurs when cells in living tissue die prematurely due to external stress or injury...
The Cancer-Protective Properties Of Milk
Date: Oct-08-2012Milk consumption has been linked to improved health, with decreased risks of diabetes, metabolic syndrome, and colon cancer. A group of scientists in Sweden found that lactoferricin4-14 (Lfcin4-14), a milk protein with known health effects, significantly reduces the growth rate of colon cancer cells over time by prolonging the period of the cell cycle before chromosomes are replicated. In a new study, investigators report that treatment with Lfcin4-14 reduced DNA damage in colon cancer cells exposed to ultraviolet (UV) light...
Neuronal Reprogramming Of Cells Of Pericytic Origin Within The Damaged Brain May Lead To Degenerated Neuron Replacement
Date: Oct-08-2012Researchers have discovered a way to generate new human neurons from another type of adult cell found in our brains. The discovery, reported in Cell Stem Cell, a Cell Press publication, is one step toward cell-based therapies for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. "This work aims at converting cells that are present throughout the brain but themselves are not nerve cells into neurons," said Benedikt Berninger, now at the Johannes Gutenberg University Mainz...
New Home Hemodialysis Systems Are Easier For Kidney Disease Patients To Use
Date: Oct-08-2012Approximately 2 million patients in the world receive some sort of dialysis treatment. Most patients with chronic kidney disease who undergo hemodialysis put up with a grueling treatment regimen that involves going into a clinic several days a week and sitting through a three-to-four hour dialysis session at each visit. Home hemodialysis is more accessible than ever, though, with the advent of newer systems that are easier for patients to learn, use, and maintain, according to a review appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN)...
Research Advances Show Promise In Curbing Infections From The Bacteria That Causes Clostridium Difficile Colitis
Date: Oct-08-2012Surgeons are making progress toward preventing initial and recurrent episodes of clostridium difficile colitis (C. difficile or C. diff), a vicious bacterial infection that is estimated to affect about 336,000 people each year, typically patients on antibiotics. Using mouse models, researchers at the Massachusetts General Hospital (MGH), Boston, found that an oral medication may prevent C. difficile infections (CDI)...
Human Stell Cells Implanted In Mice Improve Chances Of Better Therapies For Rheumatoid Arthritis
Date: Oct-08-2012Researchers at Northwestern University Feinberg School of Medicine have developed the first animal model that duplicates the human response in rheumatoid arthritis (RA), an important step that may enable scientists to discover better medicines to treat the disease. Corresponding and senior author Harris Perlman, associate professor of rheumatology at Feinberg, introduced his team's new prototype mouse model in a recent online issue of the Journal of Translational Medicine...
Parkinson's Risk Linked To Specific Genetic Variants
Date: Oct-08-2012Specific genes and changes in their expression may impact on a person's risk of developing Parkinson's disease (PD), researchers from Boston University School of Medicine (BUSM) reported in the journal PLOS ONE. The researchers say they have carried out the first ever genome-wide evaluation of genetic variants linked to Parkinson's disease. Jeanne Latourelle, DSc, and Richard H...
90 Meningitis Cases, Outbreak Update Issued By The CDC
Date: Oct-08-2012So far, there have been at least 90 cases of meningitis and 7 deaths, the Centers for Disease Control and Prevention has informed in an update on this latest outbreak that has affected 7 US states. Patients became ill with a potentially fatal form of meningitis after receiving injections in their spine with a preservative-free steroid methylprednisolone acetate - which were contaminated with fungi. The steroid is administered for the treatment of inflammation and pain...
Mental Illness Affects Job Prospects More Than Physical Disability
Date: Oct-08-2012The stigma of mental illness often has a greater impact on people's employment prospects than physical disability or illness, Australian researchers reported today. The study, commissioned by WISE Employment, a not-for-profit organization aimed at empowering job seekers to find meaningful work, revealed that mental illness, even in today's supposed period of apparent enlightenment, continues to be a serious obstacle to employment. The study was commissioned as part of Mental Health Week, which started on Sunday, October 7th, 2012...
Sleeping Brain Appears To Be Remembering Things
Date: Oct-08-2012When asleep or under anesthesia, part of the human brain behaves as if it is remembering something, researchers from UCLA reported in the journal Nature Neuroscience. The authors said that their findings go against conventional theories regarding how memory is consolidated while we sleep. Team leader, Mayank R...
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