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The Balance Between Fertility And Child Survival In The Developing World

Date: Oct-05-2012
Children in smaller families are only slightly more likely to survive childhood in high mortality environments, according to a new study of mothers and children in sub-Saharan Africa seeking to understand why women, even in the highest fertility populations in world, rarely give birth to more than eight children...

Administrative Assistant Inspires Creation Of Trojan Horse Drug Therapy For Treating Breast Cancer

Date: Oct-05-2012
When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease. An administrative assistant in the Department of Chemistry at Wake Forest University, Tuttle was more accustomed to talking to faculty and staff about meetings and course loads - not doctors' appointments and treatment plans...

Disarming Pathogens Rather Than Killing Them

Date: Oct-05-2012
A new type of antibiotic can effectively treat an antibiotic-resistant infection by disarming instead of killing the bacteria that cause it. Researchers report their findings in mBio®, the online open-access journal of the American Society for Microbiology. "Traditionally, people have tried to find antibiotics that rapidly kill bacteria...

Kidney Failure And Heart Disease In Diabetic Patients May Be Affected By Race

Date: Oct-05-2012
Diabetes is among the ten leading causes of death in both white and African American patients, but the prevalence of diabetic complications are race-specific, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). "This study is one of only a few to assess whether there is a racial difference in the incidence of diabetic complications," said Gang Hu, MD, PhD, of Pennington Biomedical Research Center in Baton Rouge, Louisiana, and lead author of the study...

New Study Indicates Possible Usefulness Of IGF-1 In Alzheimer's Disease Treatment

Date: Oct-05-2012
Low serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) are associated with Alzheimer's Disease in men, but not women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). IGF-1 and IGFBP-3 are involved in longevity and could be beneficial to cognition, especially in Alzheimer's disease where experimental studies have shown that IGF-1 opposes the main pathological processes of Alzheimer's disease...

NF1 Linked To More Than 25% Of Breast Cancers

Date: Oct-05-2012
Cancerous tumors contain hundreds of mutations, and finding these mutations that result in uncontrollable cell growth is like finding the proverbial needle in a haystack. As difficult as this task is, it's exactly what a team of scientists from Cornell University, the University of North Carolina, and Memorial Sloan-Kettering Cancer Center in New York have done for one type of breast cancer. In a report appearing in the journal GENETICS, researchers show that mutations in a gene called NF1 are prevalent in more than one-quarter of all noninheritable or spontaneous breast cancers...

Hospital Bedsores May Predict Patient Mortality

Date: Oct-05-2012
A new clinical study spearheaded by the dean of UCLA's School of Nursing has found a direct correlation between pressure ulcers - commonly known as bedsores - and patient mortality and increased hospitalization. The research is believed to be the first of its kind to use data directly from medical records to assess the impact of hospital-acquired pressure ulcers on Medicare patients at national and state levels...

Essential Updates On Evidence-Based Care In Periodontics And Implant Dentistry

Date: Oct-05-2012
What's the latest, research-supported best practice in periodontal care and implant dentistry? Dental specialists and generalists alike can read about it in the first of a new series from The Journal of Evidence-Based Dental Practice (JEBDP), the foremost publication of information about evidence-based dental practice, published by Elsevier. The inaugural edition of the Annual Report on Periodontal and Implant Treatment is now available, containing concise, authoritative reviews based on the evidence about practice-critical topics. Mark A...

The Immune System May Be Able To Boost Regeneration Of Peripheral Nerves

Date: Oct-05-2012
Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew. Influencing the macrophages immediately after injury may affect the whole cascade of biochemical events that occurs after nerve damage, potentially eliminating the need to directly stimulate the growth of axons using nerve growth factors...

New Approach That May Lead To Possible Cure For Myopia

Date: Oct-05-2012
Nearsightedness, or myopia, affects more than 40 percent of people in the U.S. and up to 90 percent of children in some parts of Asia. The problem begins in childhood and often progresses with age. Standard prescription lenses can correct the defocus but do not cure nearsightedness, and do not slow progression rates as children grow...