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Prostate Cancer That Spreads To Bones Benefits From Targeted Therapy

Date: Sep-28-2012
Prostate tumors that have spread to people's bones can be reduced in size, by a newly found cancer drug, which also helps alleviate bone pain, according to a new study. A novel cancer therapy callled Cabozantinib, which targets tumors specifically, was found to have clear and impressive results. The scientists say the trial results will be announced on September 30th at the European Society of Medical Oncology congress in Vienna...

Melatonin Helps Hypertension Patients Sleep

Date: Sep-28-2012
Beta-blockers, which are commonly given to patients with cardiovascular conditions, hypertension, and anxiety, often result in sleep issues among patients. However, researchers from Brigham and Women's Hospital have recently discovered that melatonin supplementation can improve sleep patterns among patients with hypertension who are taking beta-blockers. According to a study from 2006, beta-blockers should not be used regularly for treatment of hypertension. Melatonin, also called N-acetyl-5-methoxytryptamine, is a hormone that is closely involved in the sleeping and waking cycles...

Get Your Influenza Vaccination, The Public Is Urged

Date: Sep-28-2012
Public health officials are leading by example by getting vaccinated themselves against influenza at the NFID (National Foundation for Infectious Diseases) news conference. They urge people to do the same, and warned that nobody knows what this influenza season is going to be like. Just because last year was a mild flu season does not mean that this year will be the same. They added that even during mild seasons there are still many complications, hospitalizations and deaths from flu. Howard K. Koh, M.D., Assistant Secretary for Health at the U.S...

Benzodiazepine For Insomnia Or Anxiety Raises Dementia Risk Among Elderly

Date: Sep-28-2012
Patients over 65 years of age who take the popular insomnia and anxiety drug, benzodiazepine, have a 50% higher risk of developing dementia during the following 15 years compared to people of the same age who never took the medication, researchers reported in the BMJ (British Medical Journal). The authors say that their findings indicate that widespread indiscriminate use of benzodiazepine should be cautioned against, given the extent to which this type of medication is prescribed. Benzodiazepines have a number of potential adverse effects...

Why Is Exercise Good For Mental Health?

Date: Sep-28-2012
We all know that exercise is good for mental health, but why? What factors involved in physical activity, sports and/or exercise are good for our minds? Researchers from the Trimbos Institute in the Netherlands believe that certain psychological factors that are linked to exercise - mainly body image and social interaction - play major roles in boosting mental health. The authors, who reported their findings in the journal Clinical Psychological Science, had wanted to determine whether certain psychological factors associated with exercise played a role in boosting teenagers' mental health...

Routine Screening For Psychiatric, Cognitive, And Social Comorbidities Could Enhance Quality Of Care And Quality Of Life For People With Epilepsy

Date: Sep-28-2012
The intricate relationship between epilepsy and cognitive, psychiatric, and social problems is explored in a new paper published as part of The Lancet Series on epilepsy. Children and adults with epilepsy show an increased prevalence of psychiatric disorders (mood disorders, anxiety disorders, attention deficit hyperactive disorder (ADHD)), cognitive disorders (memory, language, problem solving) and social problems (unemployment, problematic social interactions), but the relationships between epilepsy and these complications that often occur alongside it are complex, and poorly understood...

More Than 60% Of People In Low- And Lower-Middle Income Regions Are Not Accessing Any Appropriate Epilepsy Treatment

Date: Sep-28-2012
The number of people with epilepsy in low- and lower-middle-income countries (LLMICs) is more than double that in higher-income nations, and more than 60% of people in these regions are not accessing any appropriate epilepsy treatment, according to a paper published as part of The Lancet Series on epilepsy. The paper highlights the fact that the burden of epilepsy in LLMICs is under-acknowledged by health agencies, despite the fact that treatments for this disorder are highly cost-effective...

Potential Breakthrough In Treating Type 2 Diabetes

Date: Sep-28-2012
By blocking VEGF-B, a signaling protein, fat does not accumulate in muscles and the heart, and the cells within those tissues can respond properly to insulin again, researchers from the Karolinska Institute, Sweden, the Ludwig Institute for Cancer Research, based in New York, and the Australian biopharmaceutical company CSL Limited reported in the journal Nature...

Study Provides Evidence About The Functionality Of CFTR, A Protein That Plays A Critical Role In Cystic Fibrosis

Date: Sep-28-2012
CFTR is an important protein that, when mutated, causes the life-threatening genetic disease cystic fibrosis. A study in The Journal of General PhysiologyJGP details how an accidental discovery has provided new understanding about CFTR functionality. From a scientific standpoint, CFTR is unique in that it is the only known ion channel - a protein pore that enables the passive diffusion of ions across cell membranes - in the enormous superfamily of ABC proteins, which normally operate as active transporters...

One Mystery Of Multi-Drug Tolerance Unlocked By Protein Structure

Date: Sep-28-2012
The structures of key bacterial proteins have revealed one of the biochemical secrets that enables bacteria to outwit antibiotics. In a paper published in the journal Cell Reports, Duke University School of Medicine researchers and their colleagues describe the results of a series of experiments exploring multi-drug tolerance, a phenomenon that allows bacteria to become dormant and tolerate antibiotics, only to later awaken and re-infect the host. Drug tolerance is a factor in several types of stubborn, recurring infectious diseases caused by pathogenic bacteria, such E. coli, P...