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Mechanism By Which Tumor Suppressor MIG6 Triggers Cell Suicide

Date: Sep-26-2012
Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells - a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. When cells refuse to die, and instead multiply uncontrollably, they become what we call tumors. An intricate circuitry of biochemical reactions inside cells coordinates their self-sacrifice. Tracing that circuitry is, naturally, an important part of cancer research. In a major contribution to that effort Dr...

Gene Identified For Back Pain

Date: Sep-26-2012
Researchers at King's College London have for the first time identified a gene linked to age-related degeneration of the intervertebral discs in the spine, a common cause of lower back pain. Costing the UK an estimated £7billion a year due to sickness leave and treatment costs, the causes of back pain are not yet fully understood. Until now, the genetic cause of lower back pain associated with lumbar disc degeneration (LDD) was unknown, but the largest study to date, published this week in the journal Annals of Rheumatic Diseases, has revealed an association with the PARK2 gene...

Fighting Obesity With An Immune System Molecule

Date: Sep-26-2012
Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have identified a molecule in the immune system that could affect hunger and satiety. The researchers hope that new treatments for obesity will benefit from this finding. Interleukin-6 is a chemical messenger in our immune system that plays an important role in fighting off infection. However, recent research has, surprisingly, shown that it can also trigger weight loss...

Breakthrough For IVF

Date: Sep-26-2012
Researchers at the University of Gothenburg have discovered that a chemical can trigger the maturation of small eggs to healthy, mature eggs, a process that could give more women the chance of successful IVF treatment in the future. The results have been published in the journal PloS ONE. Women and girls treated for cancer with radiotherapy and chemotherapy are often unable to have children as their eggs die as a result of the treatment. Although it is now possible to freeze eggs and even embryos, this is not an option for girls who have yet to reach puberty...

Cardiovascular Disease Prevention Should Start In Childhood

Date: Sep-26-2012
A new multi-national survey reveals the extent of misconceptions about when is the right time to start taking action to prevent cardiovascular disease (CVD). In a four-country survey sample of 4,000 adults, 49 per cent answered age 30 years or older when asked at what age they believe people should start to take action about their heart health to prevent conditions such as heart disease and stroke. The fact is that CVD can affect people of all ages and population groups, and the risk begins early in life through unhealthy diets, lack of physical activity and exposure to tobacco...

Many Europeans Still Exposed To Harmful Air Pollutants

Date: Sep-26-2012
Almost a third of Europe's city dwellers are exposed to excessive concentrations of airborne particulate matter (PM), one of the most important pollutants in terms of harm to human health as it penetrates sensitive parts of the respiratory system. The EU has made progress over the past decades to reduce the air pollutants which cause acidification, but a new report published today by the European Environment Agency (EEA) shows that many parts of Europe have persistent problems with outdoor concentrations of PM and ground level ozone...

Nanotechnology Device Aims To Prevent Malaria Deaths Through Rapid Diagnosis

Date: Sep-26-2012
A pioneering mobile device using cutting-edge nanotechnology to rapidly detect malaria infection and drug resistance could revolutionise how the disease is diagnosed and treated. Around 800,000 people die from malaria each year after being bitten by mosquitoes infected with malaria parasites. Signs that the parasite is developing resistance to the most powerful anti-malarial drugs in south-east Asia and sub-Saharan Africa mean scientists are working to prevent the drugs becoming ineffective. The €5...

Onset Of Snoring During Pregnancy Linked To Hypertension

Date: Sep-26-2012
Women who start snoring during pregnancy have an increased risk for preeclampsia and high blood pressure. Scientists from the University of Michigan discovered that pregnancy-onset snoring was significantly linked to gestational hypertension and preeclamspia in their study in the American Journal of Obstetrics and Gynecology. Previous research in 2011 has suggested that high blood pressure in pregnancy may be explained by the infiltration of white blood cells into an expectant mother's blood vessels. Louise O'Brien, Ph.D...

Bosses Experience Less Stress Than Their Subordinates

Date: Sep-26-2012
Bosses have lower levels of stress than their employees, according to a recent study by a team of Harvard and Stanford experts. The report says that the famous Shakespearean quote, "Uneasy lies the head that wears the crown," is actually very rare, because people who wear the "crown" are usually at ease more than those beneath them...

Why Do Some HIV-Positive Patients Have More Virus?

Date: Sep-26-2012
Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams than others. Their findings, detailed in a paper in this week's advance online issue of the journal Nature, could also shed light on the mystery of why some people with HIV never develop symptoms of AIDS...