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"Three-Parent IVF" Up For Public Consultation In Britain
Date: Sep-18-2012Following an invitation from the government, the UK's Human Fertilisation and Embryology Authority (HFEA) has launched a public consultation on the ethics of a new IVF technique that uses DNA from three "parents" to avoid passing on serious mitochondrial diseases. Professor Lisa Jardine is chair of the HFEA, an expert independent regulator that oversees the use of reproductive cells and embryos in fertility treatment and research...
News From The Annals Of Internal Medicine: Sept. 18. 2012
Date: Sep-18-20121. Hospital-initiated Transitional Care Interventions Can Improve Outcomes in Stroke and MI Transitional care is the treatment patients receive in between levels of care, or in between hospitalization and release to home. For chronically ill, older patients, transitional care strategies can reduce unnecessary use of health services and improve patient outcomes. Less is known about the benefits and harms of transitional care strategies for patients who have a new acute event...
Researchers Identify Principles To Support Brain Simulation Models
Date: Sep-18-2012One of the greatest challenges in neuroscience is to identify the map of synaptic connections between neurons. Called the "connectome," it is the holy grail that will explain how information flows in the brain. In a landmark paper, published the week of 17th of September in PNAS, the EPFL's Blue Brain Project (BBP) has identified key principles that determine synapse-scale connectivity by virtually reconstructing a cortical microcircuit and comparing it to a mammalian sample. These principles now make it possible to predict the locations of synapses in the neocortex...
News From The Journal Of Clinical Investigation: Sept. 17, 2012
Date: Sep-18-2012Improving pancreatic islet transplantation in humans One of the major obstacles to widespread use of pancreatic islet transplantation for the treatment of diabetes is the risk of post-transplant inflammation and immune rejection. Additionally, generalized immune suppression has many side effects and there is a need for immunosuppressive therapies that specifically target the transplant site...
Blood Test To Track Huntington's Disease Progression
Date: Sep-18-2012Huntington's disease is a fatal, inherited neurodegenerative disorder caused by a mutation in the gene encoding huntingtin. Expresion of mutant huntingtin (mHTT) protein is correlated with the onset and progression of the disease and new therapies are being developed to reduce the expression of mHTT. In order to evaluate these new therapies, researchers need to be able to quantify the amount of mHTT in a particular patient; however, non-invasive quantification of mHTT isn't currently possible...
Cancer Now Leading Cause Of Death In US Hispanics
Date: Sep-18-2012A new report from American Cancer Society researchers finds that despite declining death rates, cancer has surpassed heart disease as the leading cause of death among Hispanics in the U.S. In 2009, the most recent year for which actual data are available, 29,935 people of Hispanic origin in the U.S. died of cancer, compared to 29,611 deaths from heart disease. Among non-Hispanic whites and African Americans, heart disease remains the number one cause of death...
How Tissues And Organs Select The 'Best' Cells For Themselves, At The Expense Of 'Losers' Who Might Cause Disease
Date: Sep-18-2012Scientists from the Spanish National Cancer Research Centre (CNIO) describe how natural selection also occurs at the cellular level, and how our body's tissues and organs strive to retain the best cells in their ranks in order to fend off disease processes. These results appear in the new issue of Cell Reports. The research, carried out in the CNIO, is led by Eduardo Moreno, who is currently working at the University of Bern in Switzerland...
Trends In Rehabilitation Research In Multiple Sclerosis
Date: Sep-18-2012Nancy Chiaravalloti, PhD, an expert in cognitive rehabilitation research, authored two commentaries on trends in multiple sclerosis (MS) research. Dr. Chiaravalloti is director of Neuropsychology & Neuroscience Research at Kessler Foundation. She was recently appointed director of Traumatic Brain Injury Research at the Foundation and is principal investigator of the Northern New Jersey TBI System, a NIDRR-funded model system. Dr. Chiaravalloti is also an associate professor at UMDNJ-New Jersey Medical School...
New Study Of Stem Cell Differentiation Could Help Researchers Better Understand The Genetic Basis Of Heart Disease
Date: Sep-18-2012The fate of an embryonic stem cell, which has the potential to become any type of body cell, is determined by a complex interaction of genes, proteins that bind DNA, and molecules that modify those genes and proteins. In a new paper, biologists from MIT and the University of California at San Francisco have outlined how those interactions direct the development of stem cells into mature heart cells. The study, the first to follow heart-cell differentiation over time in such detail, could help scientists better understand how particular mutations can lead to congenital heart defects...
Reversible Method Of Tagging Proteins Developed By Chemists
Date: Sep-18-2012Chemists at UC San Diego have developed a method that for the first time provides scientists the ability to attach chemical probes onto proteins and subsequently remove them in a repeatable cycle. Their achievement, detailed in a paper that appears online in the journal Nature Methods, will allow researchers to better understand the biochemistry of naturally formed proteins in order to create better antibiotics, anti-cancer drugs, biofuels, food crops and other natural products...
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