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Most Women With Heart Disease Can Go Through Pregnancy And Delivery Safely

Date: Sep-14-2012
Results from the world's first registry of pregnancy and heart disease have shown that most women with heart disease can go through pregnancy and delivery safely, so long as they are adequately evaluated, counselled and receive high quality care. However, this is not always the case: women and babies in developing countries are more likely to die than those in developed countries where women are more likely to access better care and counselling before and during pregnancy; women with cardiomyopathy, a disease of the heart muscle, are also more affected by pregnancy...

Substantial Road Traffic Noise In Urban Areas Contributes To Sleep Disturbance And Annoyance

Date: Sep-14-2012
The World Health Organization recently recognized environmental noise as harmful pollution, with adverse psychosocial and physiological effects on public health. A new study of noise pollution in Fulton County, Georgia, suggests that many residents are exposed to high noise levels that put them at risk of annoyance or sleep disturbance, which can have serious health consequences. The research is published in the October issue of American Journal of Preventive Medicine. "Our research estimated that the percentage of the overall populations at risk of high annoyance is 9...

Active Follow-Up With Telephone Help Can Reduce Deaths In Chronic Heart Failure Patients

Date: Sep-14-2012
Chronic heart failure (CHF) patients are less likely to have died a year after discharge if they are involved in a programme of active follow-up once they have returned home than patients given standard care, according to a new Cochrane systematic review. These patients were also less likely to need to go back into hospital in the six months that follow discharge. CHF is a serious condition, mainly affecting elderly people. It is becoming increasingly common as the population ages, and carries high risks of emergency hospitalisation and death...

New Discovery Related To Gum Disease

Date: Sep-14-2012
A University of Louisville scientist has found a way to prevent inflammation and bone loss surrounding the teeth by blocking a natural signaling pathway of the enzyme GSK3b, which plays an important role in directing the immune response. The discovery of UofL School of Dentistry researcher David Scott, PhD, and his team recently published on-line first in the journal Molecular Medicine. The finding not only has implications in preventing periodontal disease, a chronic inflammatory disease that causes tooth loss, but also may have relevance to other chronic inflammatory diseases...

Breast Cancer Risks Acquired In Pregnancy May Pass To Next 3 Generations

Date: Sep-14-2012
Chemicals or foods that raise estrogen levels during pregnancy may increase cancer risk in daughters, granddaughters, and even great-granddaughters, according to scientists from Virginia Tech and Georgetown University. Pregnant rats on a diet supplemented with synthetic estrogen or with fat, which increases estrogen levels, produce ensuing generations of daughters that appear to be healthy, but harbor a greater than normal risk for mammary cancer, the researchers report in today's Nature Communications...

Study Provides Insight Into Why Severely Obese Women Have Difficulty Getting Pregnant From IVF

Date: Sep-14-2012
One third of American women of childbearing age are battling obesity, a condition that affects their health and their chances of getting pregnant. Obese women often have poor reproductive outcomes, but the reasons why have not been clearly identified. Now, a novel study led by Catherine Racowsky, PhD, director of the Assisted Reproductive Technologies Laboratory at Brigham and Women's Hospital (BWH), and performed by Ronit Machtinger, M.D., of BWH, in collaboration with Catherine Combelles, PhD, of Middlebury College, gains further insight into the underlying mechanisms...

Improved Nanoparticles Deliver Drugs Into Brain

Date: Sep-14-2012
The brain is a notoriously difficult organ to treat, but Johns Hopkins researchers report they are one step closer to having a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and perhaps other maladies affecting that organ. In a report published online on August 29 in Science Translational Medicine, the Johns Hopkins team says its bioengineers have designed nanoparticles that can safely and predictably infiltrate deep into the brain when tested in rodent and human tissue...

BYU Biochemistry Professor And Students Solve A Birth-Defect Mystery

Date: Sep-14-2012
The cellular cause of birth defects like cleft palates, missing teeth and problems with fingers and toes has been a tricky puzzle for scientists. Now Professor Emily Bates and her biochemistry students at Brigham Young University have placed an important piece of the developmental puzzle. They studied an ion channel that regulates the electrical charge of a cell. In a new study published by the journal Development, they show that blocking this channel disrupts the work of a protein that is supposed to carry marching orders to the nucleus...

Beacons Light Up Stem Cell Transformation

Date: Sep-14-2012
A novel set of custom-designed "molecular beacons" allows scientists to monitor gene expression in living populations of stem cells as they turn into a specific tissue in real-time. The technology, which Brown University researchers describe in a new study, provides tissue engineers with a potentially powerful tool to discover what it may take to make stem cells transform into desired tissue cells more often and more quickly. That's a key goal in improving regenerative medicine treatments...

Stroke Risk Increases In Men With Divorced Parents

Date: Sep-14-2012
Men from divorced families have a higher chance of suffering a stroke than men from families that are still intact. According to the study, from the University of Toronto and published this month in the International Journal of Stroke, adult men have a 3 times higher chance to stroke if their parents were divorced before they reached 18, compared to those whose parents were together. On the contrary, women who have divorced parents have no greater risk of stroke than other females from intact families...