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Following Orthopaedic Surgery Or Trauma, Anti-Clotting Therapy May Be Used Too Often

Date: Sep-04-2012
Some smaller clots may not require potentially risky treatment Men and women who undergo joint replacement procedures, as well as those who have significant fractures, tend to be at an increased risk of developing pulmonary emboli (PE), blood clots that travel to the lungs where they may cause serious complications and even death...

Smoking Prevention Programs Still Critical For Adolescents

Date: Sep-04-2012
While many might see the case for programs to prevent adolescent cigarette smoking as already made, a pair of Wayne State University researchers believes that due to increasingly challenging economic times, policymakers need to be reminded to continue allocating funding for such programs. Xinguang Chen, M.D., Ph.D., professor of pediatrics in the School of Medicine, and Feng Lin, Ph.D., professor of electrical and computer engineering in the College of Engineering, have found a way to provide policymakers with some hard evidence...

Gastrointestinal Stromal Tumor Treatment Regorafenib Submitted To FDA

Date: Sep-04-2012
Bayer Also Initiates Expanded Access Program for Patients Diagnosed with GIST Bayer HealthCare and Onyx Pharmaceuticals (NASDAQ: ONXX) has announced that Bayer HealthCare has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the oral multi-kinase inhibitor regorafenib for the treatment of metastatic and/or unresectable gastrointestinal stromal tumors (GIST) in patients whose disease has progressed despite prior treatment. Regorafenib is a Bayer compound developed by Bayer. In 2011, Bayer entered into an agreement with Onyx Pharmaceuticals, Inc...

Compound Interacts With Receptor In Brain That Plays Role In Neurodegenerative Processes In Alzheimer's Disease

Date: Sep-04-2012
A compound developed to treat neuropathic pain has shown potential as an innovative treatment for Alzheimer's disease, according to a study by researchers at Cleveland Clinic's Lerner Research Institute and Anesthesiology Institute. "Cleveland Clinic dedicated two years of research into the examination of this compound and our findings show it could represent a novel therapeutic target in the treatment of Alzheimer's disease," said Mohamed Naguib, M.D., Professor of Anesthesiology, Cleveland Clinic Lerner College of Medicine...

Electrical Engineers Demonstrate The Feasibility Of A Millimeter-Sized, Wirelessly Powered Cardiac Device

Date: Sep-04-2012
A team of engineers at Stanford has demonstrated the feasibility of a super-small, implantable cardiac device that gets its power not from batteries, but from radio waves transmitted from outside the body. The implanted device is contained in a cube just eight-tenths of a millimeter in radius. It could fit on the head of pin. The findings were published in the journal Applied Physics Letters...

If People Don't Take Their Health Into Their Own Hands, Governments May Use Policies To Do It For Them

Date: Sep-04-2012
Obesity rates in North America are a growing concern for legislators. Expanded waistlines mean rising health-care costs for maladies such as diabetes, heart disease and some cancers. One University of Alberta researcher says that if people do not take measures to get healthy, they may find that governments will throw their weight into administrative measures designed to help us trim the fat. Nola Ries of the Faculty of Law's Health Law and Science Policy Group has recently published several articles exploring potential policy measures that could be used to promote healthier behaviour...

Discovery Of Genetic Link To Prostate Cancer Risk In African Americans

Date: Sep-04-2012
Prostate cancer in African-American men is associated with specific changes in the IL-16 gene, according to researchers at the University of Illinois at Chicago College of Medicine. The study, published online in the journal Cancer Epidemiology, Biomarkers & Prevention, establishes the association of IL-16 with prostate cancer in men of both African and European descent. "This provides us with a new potential biomarker for prostate cancer," says principal investigator Rick Kittles, UIC associate professor of medicine in hematology/oncology...

Discovery Of The Molecular Root Cause Of The Euphoric Phases That Occur In Bipolar Disorder

Date: Sep-04-2012
Flying high, or down in the dumps - individuals suffering from bipolar disorder alternate between depressive and manic episodes. Researchers from the University of Bonn and the Central Institute of Mental Health in Mannheim have now discovered, based on patient data and animal models, how the NCAN gene results in the manic symptoms of bipolar disorder. The results have been published in the current issue of The American Journal of Psychiatry. Individuals with bipolar disorder are on an emotional rollercoaster...

Falls Prevention: New Physio Guidelines For Seniors At Risk

Date: Sep-04-2012
Taking a fall in older life can not only result in injury, but also a potentially debilitating loss of confidence. But new guidelines for physiotherapists, co-compiled by a leading academic in the field from the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, aim to refresh out-dated guidelines and introduce better direction for physiotherapists who work with elderly people at risk of falling. As we get older our risk of falling increases, regardless of environment and social background - King Juan Carlos of Spain is a high profile example...

New Intriguing Knowledge On Blood Haemoglobin Published

Date: Sep-04-2012
Scientists at the research centre MEMBRANES at Aarhus University, Denmark, have completed an old puzzle, which has been regarded as impossible to complete since the 60s. The challenge was to solve the structure of the protecting protein complex that forms when haemoglobin is released from red cells and becomes toxic. This toxic release of haemoglobin occurs in many diseases affecting red cell stability, e.g. malaria. Technically, the most important finding in this report in Nature is a high-resolution three-dimensional mapping of the so-called 'haptoglobin-haemoglobin complex'...