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New Blood Test Helps Determine Who Benefits Most From Implantable Cardioverter Defibrillators
Date: Aug-27-2012Some heart failure patients benefit from having an implantable cardioverter defibrillator (ICD) while others do not - a new blood test that predicts risk of death may help doctors determine who should get an ICD, Professor Samuel Dudley, from the University of Illinois at Chicago College of Medicine explained at the European Society of Cardiology Congress 2012, in Munich, Germany. An estimated 5 million people in the USA suffer from heart failure, a condition where not enough blood is pumped around the body...
Heart Failure Patients With Preserved Ejection Fraction May Benefit From New Drug, LCZ696
Date: Aug-27-2012LCZ696, a first-in-class compound, may improve treatment outcomes for half of all patients with heart failure, according to a Phase II clinical trial on heart failure patients with preserved ejection fraction; preserved ejection fraction is when all the heart failure signs are present, but the heart's left ventricle pumps out more blood when it contracts compared to others with heart failure. Dr Scott Solomon and team, of the Brigham and Women's Hospital, USA, presented the human study results at the European Society of Cardiology 2012 Annual Congress, in Munich, Germany...
Sudden Cardiac Death Less Likely If You're Exercising
Date: Aug-27-2012There is a smaller chance of dying from sudden cardiac arrest if it is exercise-related, than cardiac arrests for other reasons, researchers from The Netherlands reported at the European Society for Cardiology 2012 Congress, in Munich, Germany. Dr Arend Mosterd, and team from the Academic Medical Center, University of Amsterdam, presented their findings from ARREST (the Amsterdam Resuscitation Study). The study has been published in Circulation...
Merck Aims For Two Cardiovascular Medication Approvals Next Year
Date: Aug-27-2012Merck & Co announced yesterday that it is aiming for the approval of two cardiovascular drugs in the United States and the European Union for 2013. The two drugs are vorapaxar, an experimental drug for acute coronary syndrome chest pain caused by coronary artery disease, and K-524A (tredaptive), for the treatment of HDL (bad cholesterol) to reduce the incidence of vascular events. The company made the announcement at the European Society for Cardiology 2012 Congress, in Munich, Germany...
Gallstone Risk Higher Among Obese Children And Teenagers
Date: Aug-27-2012Obese and overweight children or teenagers have a considerably higher risk of developing gallstones compared to their peers of normal weight, researchers from Kaiser Permanente, USA, reported in the Journal of Pediatric Gastroenterology & Nutrition. Gallstones are not usually seen in kids, the researchers added...
Racial Disparities In Prostate Cancer Care
Date: Aug-27-2012A study led by investigators from Vanderbilt-Ingram Cancer Center (VICC), Nashville, Tenn., finds that black men with prostate cancer receive lower quality surgical care than white men. The racial differences persist even when controlling for factors such as the year of surgery, age, comorbidities and insurance status. Daniel Barocas, M.D., MPH, assistant professor of Urologic Surgery, is first author of the study published in the Journal of Urology...
Balancing Quality And Quantity Of Life For Pancreatic Cancer Patients
Date: Aug-27-2012Every year, nearly 45,000 Americans are diagnosed with pancreatic cancer. The odds against those stricken by the disease are truly dismal; pancreatic cancer almost always kills within two years after diagnosis, no matter how it is treated. Even aggressive intervention with chemotherapy, radiation or surgery rarely yields more than an extra month to a year of survival, depending on the stage of the disease...
Project Helps Decision Makers Address Issues Related To Urban Pollution, Human Comfort
Date: Aug-27-2012Cities - with their concrete canyons, isolated greenery, and congested traffic - create seemingly chaotic and often powerful wind patterns known as urban flows. Carried on these winds are a variety of environmental hazards, including exhaust particles, diesel fumes, chemical residues, ozone, and the simple dust and dander produced by dense populations...
Researchers Identify PHF20, A Regulator Of Gene P53, Critical For Normal Cell Growth And Tumor Suppression
Date: Aug-27-2012Researchers at Moffitt Cancer Center and colleagues have identified PHF20, a novel transcriptional factor, and clarified its role in maintaining the stability and transcription of p53, a gene that allows for both normal cell growth and tumor suppression. PHF20, the researchers found, plays a previously unknown and unique role in regulating p53. When p53 is activated, it can mend DNA damage and eliminate cancer cells by binding to DNA...
Blood Flow In Brain Rebooted By Nanoparticles
Date: Aug-27-2012A nanoparticle developed at Rice University and tested in collaboration with Baylor College of Medicine (BCM) may bring great benefits to the emergency treatment of brain-injury victims, even those with mild injuries. Combined polyethylene glycol-hydrophilic carbon clusters (PEG-HCC), already being tested to enhance cancer treatment, are also adept antioxidants. In animal studies, injections of PEG-HCC during initial treatment after an injury helped restore balance to the brain's vascular system. The results were reported this month in the American Chemical Society journal ACS Nano...
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