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Cancer Prevention, Treatment By Targeting Inflammation
Date: Aug-25-2012Researchers at the Georgia Health Sciences University Cancer Center have identified a gene that disrupts the inflammatory process implicated in liver cancer. Laboratory mice bred without the gene lacked a pro-inflammatory protein called TREM-1 and protected them from developing liver cancer after exposure to carcinogens. The study, published in Cancer Research, a journal for the American Association for Cancer Research, could lead to drug therapies to target TREM-1, said Dr. Anatolij Horuzsko, an immunologist at the GHSU Cancer Center and principal investigator on the study...
The Molecular Cogs Of Clock Genes Responsive To Temperature Variations
Date: Aug-25-2012Numerous processes in our body fluctuate in a regular pattern during the day. These circadian (or daily) variations can be driven by local oscillators present within our cells or by systemic signals controlled by the master pacemaker, located in the brain. Ueli Schibler, professor at the University of Geneva (UNIGE), Switzerland, unveils a molecular mechanism by which body temperature rhythms influence the expression of 'clock genes' and synchronize local oscillators...
Shedding New Light On Alcohol-Related Birth Defects
Date: Aug-25-2012A collaborative research effort by scientists at the University of North Carolina School of Medicine, Duke University, and University College of London in the UK, sheds new light on alcohol-related birth defects. The project, led by Kathleen K. Sulik, PhD, a professor in the Department of Cell and Developmental Biology and the Bowles Center for Alcohol Studies at UNC, could help enhance how doctors diagnose birth defects caused by alcohol exposure in the womb. The findings also illustrate how the precise timing of that exposure could determine the specific kinds of defects...
New Approach To Fighting Viral Illnesses
Date: Aug-25-2012By discovering how certain viruses use their host cells to replicate, UC Irvine microbiologists have identified a new approach to the development of universal treatments for viral illnesses such as meningitis, encephalitis, hepatitis and possibly the common cold. The UCI researchers, working with Dutch colleagues, found that certain RNA viruses hijack a key DNA repair activity of human cells to produce the genetic material necessary for them to multiply...
CWRU Dental Study Links Moms To Teen Oral Health
Date: Aug-25-2012A mother's emotional health and education level during her child's earliest years influence oral health at age 14, according to a new study from Case Western Reserve University's School of Dental Medicine. Researchers started with the oral health of the teens and worked backwards to age 3 to find out what factors in their past influenced their oral health outcomes. While mothers were interviewed, lead investigator Suchitra Nelson, professor in the dental school, believes it can apply to whoever is the child's primary caregiver...
Study Reveals Gene Activity In The Brain Which Could Deepen Understanding Of Human Diseases
Date: Aug-25-2012More sophisticated wiring, not just bigger brain, helped humans evolve beyond chimps Human and chimp brains look anatomically similar because both evolved from the same ancestor millions of years ago. But where does the chimp brain end and the human brain begin? A new UCLA study pinpoints uniquely human patterns of gene activity in the brain that could shed light on how we evolved differently than our closest relative...
Non-Valvular Artial Fibrillation Drug Xarelto® (Rivaroxaban), Studies Investigate Benefits
Date: Aug-25-2012Patients with Atrial Fibrillation (AF) who undergo cardioversion or catheter ablation therapy are at particular risk of stroke and require effective anticoagulation before and after these procedures. Xarelto is indicated for the prevention of stroke and systemic embolism in eligible adult patients with non-valvular atrial fibrillation with one or more risk factors such as: congestive heart failure, hypertension, age�75 years, diabetes mellitus and prior stroke or transient ischaemic attack...
New Imaging Technique Reveals The Brain's Continuous Renovation On Video
Date: Aug-25-2012Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell...
ABC's For New Parents From Dermatologists
Date: Aug-24-2012First-time parents have quite the scare while they rush into the emergency room or call their doctors after-hours after they see odd rashes, suspicious crusting and bumps that appear on their newborn baby out of the blue, however, they are very common, easy to treat, and rarely mean anything is seriously wrong. Kate Püttgen, M.D., Johns Hopkins Children's Center dermatologist, said: "Neonatal rashes tend to develop suddenly and have a dramatic appearance that can easily frighten a rookie parent, but luckily most of these are completely benign...
Obese Youth Have Significantly Higher Risk Of Gallstones
Date: Aug-24-2012Girls and Hispanic Youth at Higher Risk of Disease Usually Seen in Adults Children who are overweight or obese face an increased risk for gallstones, according to a Kaiser Permanente study published in the Journal of Pediatric Gastroenterology & Nutrition. Researchers found that children and adolescents who were overweight were twice as likely to have gallstone disease, compared to children and adolescents who had a normal body mass index...
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