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Heart Risk Prediction Improves With Calcium Scan
Date: Aug-24-2012A review of six screening tools for identifying people at high risk for heart disease who are misclassified as intermediate risk using the current standard, suggests the best one is a CT scan that looks for calcium build-up in the arteries around the heart. The review is published this week in the Journal of the American Medical Association, JAMA. The lead author is Joseph Yeboah, assistant professor of cardiology at Wake Forest Baptist Medical Center in Winston-Salem, North Carolina...
Urgent Need For More Research, Funding Highlighted By Deadly Outbreak Of West Nile Virus
Date: Aug-24-2012Mosquito-borne West Nile virus (WNV) caused 26 deaths already this year, and nearly 700 cases had been reported by mid-August according to the Centers for Disease Control and Prevention (CDC). WNV had become "old news" among the public and the media. Furthermore, funding to support research, training and education, and surveillance and vector control had waned. Now there is an urgent imperative to redouble our efforts to understand and control this dangerous virus. Vector-Borne and Zoonotic Diseases*, a major peer-reviewed journal from Mary Ann Liebert, Inc...
Food Insecurity, Poor Nutrition Increases Hospital Use By HIV-Infected Urban Poor In SF
Date: Aug-24-2012UCSF researchers found that poor HIV-infected individuals living in San Francisco are significantly more likely to visit emergency rooms and to have hospital stays if they lack access to food of sufficient quality and quantity for a healthy life. "In the prior three months, a quarter of participants in the study reported an ER visit, and just over a tenth reported a hospitalization, which shows that we are dealing with a population with high levels of illness...
Improving Understanding Of The Mechanism Involved In The Development Of Drug Resistance In Tuberculosis
Date: Aug-24-2012Edward Yu took note of the facts - nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally drug-resistant strains - and decided to shift his research focus to tuberculosis. Yu, an Iowa State University and Ames Laboratory researcher, has described in the journal Nature the three-part structure that allows E. coli bacteria to pump out toxins and resist antibiotics...
Unique Adverse Events With Newly Approved Drug Reviewed By Melanoma Expert
Date: Aug-24-2012An internationally recognized melanoma researcher at Moffitt Cancer Center and colleagues at the University of Kiel in Germany, including Axel Hauschild, M.D., and Katharina C. Kahler, M.D., have published an article in the Journal of Clinical Oncology that describes immune-related adverse events for patients receiving either tremelimumab or ipilimumab. Both drugs are anti-CTLA-antibodies with similar mechanisms of action but manufactured by different companies. Ipilimumab is an immunoglobulin G1 with a plasma half-life of 12 to 14 days...
Intravenous Administration Of Green Tea Compound Shows Promise For Tackling Cancer
Date: Aug-24-2012A compound found in green tea could be a weapon in treatments for tackling cancer, according to newly-published research at the University of Strathclyde in Glasgow, Scotland. The extract, known as epigallocatechin gallate, has been known to have preventative anti-cancer properties but fails to reach tumours when delivered by conventional intravenous administration. However, in initial laboratory tests at the Universities of Strathclyde and Glasgow, researchers used an approach which allowed the treatment to be delivered specifically to the tumours after intravenous administration...
New Research Could Reduce Risks For People Who Work With Tiny Fibres Used In Manufacturing Industries
Date: Aug-24-2012Research into the health risks posed by nanofibres - used to strengthen objects from tennis rackets to airplane wings - has pinpointed the lengths at which these fibres are harmful to the lungs. Health risks Nanofibres, which can be made from a range of materials including carbon, are about 1,000 times smaller than the width of a human hair and can reach the lung cavity when inhaled. This may lead to a cancer known as mesothelioma, which is known to be caused by breathing in asbestos fibres, which are similar to nanofibres...
Exposing Male Mice To Chronic Social Stress Results In Anxious Female Offspring
Date: Aug-24-2012A study in mice conducted by researchers at Tufts University School of Medicine (TUSM) suggests that a woman's risk of anxiety and dysfunctional social behavior may depend on the experiences of her parents, particularly fathers, when they were young. The study, published online in Biological Psychiatry, suggests that stress caused by chronic social instability during youth contributes to epigenetic changes in sperm cells that can lead to psychiatric disorders in female offspring across multiple generations. "The long-term effects of stress can be pernicious...
Small Bowel X-Rays, CT Enterography May Be Replaced By MR Enterography For Pediatric Patients With Crohn Disease
Date: Aug-24-2012Parents with children nine years old and older who have Crohn disease should ask their children's doctor about MR enterography as a replacement for small bowel x-rays or CT enterography, a new study indicates. Children with inflammatory bowel disease must often undergo repeated examinations, which, with x-rays and CT, could lead to significant radiation exposure, said William A. Faubion, Jr., MD, one of the authors of the study...
Blood Cells Returned To Stem Cell State
Date: Aug-24-2012Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body. The work, described in the journal Public Library of Science (PLoS), is "Chapter Two" in an ongoing effort to efficiently and consistently convert adult blood cells into stem cells that are highly qualified for clinical and research use in place of human embryonic stem cells, says Elias Zambidis, M.D., Ph.D...
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