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New Ebola Outbreak In Uganda
Date: Aug-14-2012A new case of Ebola was confirmed on July 28, 2012 in Uganda. The World Health Organization (WHO), located in Kampala, immediately went into action in order to prevent the disease from spreading. Their response was to isolate confirmed cases using lab testing, educate the public about the virus, provide treatment support and follow up with contacts. The Ebola virus causes Ebola hemorrhagic fever, an extremely infectious virus that easily spreads by direct contact with bodily fluids. The virus is passed from wild animals to people...
Rare Risk Of Severe Liver Injury In Older Patients From Common Antibiotics
Date: Aug-14-2012The commonly used broad-spectrum antibiotics moxifloxacin and levofloxacin are associated with an increased risk of severe liver injury in older people, according to a new study published in CMAJ (Canadian Medical Association Journal). Moxifloxacin and levofloxacin are commonly prescribed "fluoroquinolone" antibiotics often used for bacterial infections such as respiratory infections, sinus infections and others...
Protective Bacteria In The Infant Gut Have Resourceful Way Of Helping Babies Break Down Breast Milk
Date: Aug-14-2012A research team at the University of California, Davis, has found that important and resourceful bacteria in the baby microbiome can ferret out nourishment from a previously unknown source, possibly helping at-risk infants break down components of breast milk. Breast milk is amazingly intricate, providing all of the nutrients necessary to sustain and strengthen infants in the first months of life. Moreover, this natural source of nutrition provides protection from infections, allergies and many other illnesses...
Personalized Cancer Care Via Chromosomal Translocations
Date: Aug-14-2012A broken chromosome is like an unmoored beansprout circling in search of attachment. If a cell tries to replicate itself with broken chromosomes, the cell will be killed and so it would very much like to find its lost end. Often, it finds a workable substitute: another nearby chromosome. When a broken chromosome attaches to another, or when chromosomes use a similar process to exchange genetic material, you have a translocation - genes end up fused to other genes, encoding a new protein they shouldn't...
Hope For Improved Treatment For Acute Myeloid Leukemia Following Gene Discovery
Date: Aug-14-2012Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a step closer to new treatment options. Their study results were published online in Cancer Cell. "We have discovered that a gene called HLX is expressed at abnormally high levels in leukemia stem cells in a mouse model of AML," said Ulrich Steidl, M.D., Ph.D., assistant professor of cell biology and of medicine at Einstein and senior author of the paper...
Muscle Atrophy: Researchers Identify Key Culprit
Date: Aug-14-2012Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle - even slight or gradual - is about as common to the human condition as breathing. Yet despite its everyday nature, scientists know little about what causes skeletal muscles to atrophy. They know proteins are responsible, but there are thousands of possible suspects, and parsing the key actors from the poseurs is tricky. In a new paper, researchers from the University of Iowa report major progress...
Discovery Of Molecule That Controls Tumor Vessel Maturation Could Lead To More Effective Cancer Drugs
Date: Aug-14-2012Sanford-Burnham researchers discover molecule that controls tumor vessel maturation -- a counterintuitive approach that could improve cancer drug delivery To survive, tumors need blood supply to provide them with nutrients and oxygen. To get that supply, cancer cells stimulate new blood vessel growth - a process called tumor angiogenesis. Many attempts have been made to inhibit this process as a means to choke off tumors. But tumor angiogenesis can be sloppy, resulting in immature and malformed blood vessels...
Alzheimer's Blood Test - Scientists Closing In
Date: Aug-14-2012Scientists are a step closer to developing a blood test for Alzheimer's disease following the publication online this month in Neurology of a new study that found four biomarkers showed consistent results across three independent groups of patients. Current methods for diagnosing Alzheimer's are based mainly on clinical symptoms that often have to be confirmed with expensive PET scans, or by testing for beta-amyloid protein in samples of cerebrospinal fluid with a procedure that can be painful and distressing...
Intervention By Bystanders Helps Put A Stop To Bullying
Date: Aug-14-2012With new national anti-bullying ads urging parents to teach their kids to speak up if they witness bullying, one researcher has found that in humans' evolutionary past at least, helping the victim of a bully hastened our species' movement toward a more egalitarian society. Humans have evolved a genetically-controlled drive to help weaker individuals fight back against a bully...
News From The Journal Of Clinical Investigation: Aug. 13, 2012
Date: Aug-14-2012New class of proteins allows breast cancer cells to evade Tyrosine Kinase Inhibitors Aberrant regulation of cell growth pathways is required for normal cells to become cancerous, and in many types of cancer, cell growth is driven by a group of enzymes known as receptor tyrosine kinases (RTKs). The RTK epidermal growth factor receptor (EGFR) is overexpressed in over 30% of breast cancers; however, drugs that target RTKs, known as tyrosine kinase inhibitors (TKIs) have not been effective in treating breast cancer...
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