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Improving Human Immunity To Malaria

Date: Aug-03-2012
The deadliest form of malaria is caused the protozoan Plasmodium falciparum. During its life-cycle in human blood, the parasite P. falciparum expresses unique proteins on the surface on infected blood cells. Antibodies to these proteins are associated with protection from malaria, however, the identity of surface protein(s) that elicit the strongest immune response is unknown. Dr. James Beeson and colleagues at the Walter and Eliza Hall Institute of Medical Research in Victoria, Australia have developed novel assays with transgenic P...

Disease Management Programme Module On Heart Failure: Current Guidelines Indicate Some Need For Revision

Date: Aug-03-2012
On 14 February 2012, the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based clinical practice guidelines on the treatment of people with heart failure. The aim of the report is to identify those recommendations from current guidelines of high methodological quality that may be relevant for the planned revision of the module "heart failure" in the disease management programme (DMP) for coronary heart disease (CHD)...

Insomnia Now Affecting An Estimated 150 Million In Developing World

Date: Aug-03-2012
Levels of sleep problems in the developing world are approaching those seen in developed nations, linked to an increase in problems like depression and anxiety. According to the first ever pan-African and Asian analysis of sleep problems, led by Warwick Medical School at the University of Warwick, an estimated 150 million adults are suffering from sleep-related problems across the developing world. See Graph. The results are published in a study in the journal Sleep. Warwick Medical School researchers have found a rate of 16...

Medical Staff Often Miss Alcohol Problems If Patients Are Not Intoxicated

Date: Aug-03-2012
Medical staff struggle to spot problem drinking in their patients unless they are already intoxicated, according to research by the University of Leicester. The work led by Dr Alex J Mitchell, consultant at Leicestershire Partnership NHS Trust and honorary senior lecturer at the University, reveals that clinical staff often overlook alcohol problems in their patients when they do not present intoxicated...

Cause Of Death: Anorexia - In Fruit Flies On Methamphetamine

Date: Aug-03-2012
A new study finds that fruit flies exposed to methamphetamine drastically reduce their food intake and increase their physical activity, just as humans do. The study, which tracked metabolic and behavioral changes in fruit flies on meth, indicates that starvation is a primary driver of methamphetamine-related death in the insects. The new findings are described in The Journal of Toxicological Sciences. The abuse of methamphetamine can have significant harmful side effects in humans. It burdens the body with toxic metabolic byproducts and weakens the heart, muscles and bones...

Molecular Link Between Circadian Clock Disturbances And Inflammatory Diseases

Date: Aug-03-2012
Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer. Researchers at the Salk Institute for Biological Studies have now found a possible molecular link between circadian rhythm disturbances and an increased inflammatory response...

Study Reveals New Effects Of The Investigational Multiple Sclerosis Drug Daclizumab

Date: Aug-03-2012
Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation for treating MS - daclizumab - and could lead to a new class of drugs for treating MS and other autoimmune disorders. In these disorders, the immune system turns against the body's own tissues...

The Benefits Of Deworming HIV-Infected Children

Date: Aug-03-2012
HIV care centers are an important and highly accessed point of care for HIV-infected children and their families in sub-Saharan Africa, but opportunities to address other health issues are being missed. Proven interventions, including routine deworming among young children, could be effectively integrated into HIV care according to a newly published article in PLoS by University of Washington researchers...

Vaginal Pain May Mean Irritable Bowl Syndrome Or Fibromyalgia

Date: Aug-02-2012
Unexplained vulvar pain, also known as vulvodynia, affects millions of women worldwide. It can be so severe that it makes exercise, intercourse and even sitting unbearable. A new study published in the journal American College of Obstetricians and Gynecologists has now revealed that women who suffer from this painful vaginal condition have a 2 to 3 times higher risk of also developing other chronic pain conditions, such as irritable bowel syndrome, interstitial cystitis known as and fibromyalgia or musculoskeletal pain...

How To Protect Your Family From West Nile Virus

Date: Aug-02-2012
Every summer, outbreaks of West Nile virus disease occur in the U.S. This year, some parts of the country are experiencing earlier and greater activity, and the Centers for Disease Control and Prevention is urging people to take preventive steps to protect against West Nile virus infections. Infected mosquitoes transmit the West Nile virus to people. The main season for infections in the U.S. is generally between June and September, with a peak in mid-August...