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Mortality Risk Doubled By Amnestic Mild Cognitive Impairment
Date: Jul-17-2012Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that people with a form of mild cognitive impairment (MCI), a risk factor for developing Alzheimer's disease, have twice the risk of dying compared with cognitively normal people. Those with dementia have three times the risk. The findings are being presented at the Alzheimer's Association International Conference in Vancouver this week...
The Health Benefits Of Living By The Sea
Date: Jul-17-2012A new study from the European Centre for Environment & Human Health, Peninsula College of Medicine and Dentistry, University of Exeter, has revealed that people living near the coast tend to have better health than those living inland. Researchers from the Centre used data from the UK's census to examine how health varied across the country, finding that people were more likely to have good health the closer they live to the sea. The analysis also showed that the link between living near the coast and good health was strongest in the most economically deprived communities...
Newest Blood-Thinning Drug Recommended For Unstable Angina In Updated AHA/ACCF Guidelines
Date: Jul-17-2012Ticagrelor, a blood-thinning drug approved by the FDA in 2011, should be considered along with older blood thinners clopidogrel and prasugrel for treating patients who are experiencing chest pain or some heart attacks, according to joint updated guidelines issued by the American Heart Association (AHA) Task Force on Practice Guidelines and the American College of Cardiology (ACCF) Foundation...
Racial Disparities In Voice Box Preserving Cancer Treatment
Date: Jul-17-2012A new epidemiological study led by UC Davis researchers reveals significant racial disparities in the use of non-surgical larynx-preservation therapy for locally advanced laryngeal cancer. A review of medical records between 1991 and 2008 from across the country reveals that over 80 percent of white patients received radiation treatment combined with chemotherapy that preserves the larynx, or voice box. Only 74...
Matching Cancer Drugs With Gene Targets
Date: Jul-17-2012A new study details how a suite of web-based tools provides the research community with greatly improved capacity to compare data derived from large collections of genomic information against thousands of drugs. By comparing drugs and genetic targets, researchers can more easily identify pharmaceuticals that could be effective against different forms of cancer. The newly updated software, called CellMiner, was built for use with the NCI-60, one of the most widely utilized collections of cancer cell samples employed in the testing of potential anti-cancer drugs...
Pre-Injury Cartilage Biomarkers Associated With Subsequent Anterior Cruciate Ligament Injuries
Date: Jul-17-2012U.S. Army researchers made a surprising discovery while examining the impact of an anterior cruciate ligament (ACL) tear (a common knee injury), on four serum biomarkers associated with cartilage health. The researchers found that pre-injury concentrations for all but one of the four serum biomarkers studied were associated with the subsequent likelihood of ACL injury. The findings were presented at the annual meeting of the American Orthopaedic Society for Sports Medicine (AOSSM)...
Mosquitoes Prevented From Transmitting Malaria Through Genetic Modification Of Their Gut Bacteria
Date: Jul-17-2012Researchers at the Johns Hopkins Malaria Research Institute have genetically modified a bacterium commonly found in the mosquito's midgut and found that the parasite that causes malaria in people does not survive in mosquitoes carrying the modified bacterium. The bacterium, Pantoea agglomerans, was modified to secrete proteins toxic to the malaria parasite, but the toxins do not harm the mosquito or humans. According to a study published by PNAS, the modified bacteria were 98 percent effective in reducing the malaria parasite burden in mosquitoes...
Brain Maps Created During Study Of Aging Reveal That Alzheimer's Patients Drive Differently
Date: Jul-17-2012Activity lingers longer in certain areas of the brain in those with Alzheimer's than it does in healthy people, Mayo Clinic researchers who created a map of the brain found. The results suggest varying brain activity may reduce the risk of Alzheimer's disease. The study, "Non-stationarity in the "Resting Brain's" Modular Architecture," was presented at the Alzheimer's Association International Conference and recently published in the journal PLoS One. Researchers compared brain activity to a complex network, with multiple objects sharing information along pathways...
How The Intrauterine Environment Molds The Human Epigenome Could Provide Critical Information About Disease Risk
Date: Jul-17-2012Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime. In a study published online in Genome Research, researchers have for the first time shown that the environment experienced in the womb defines the newborn epigenetic profile, the chemical modifications to DNA we are born with, that could have implications for disease risk later in life...
New Method For Identifying Lung Nodules
Date: Jul-17-2012Pulmonary nodules are common, but few studies of lung nodule identification and clinical evaluation have been performed in community settings. Researchers from Kaiser Permanente Southern California identified 7,112 patients who had one or more nodules by using existing information within the electronic medical record. Their study presented in the August 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed how researchers developed and implemented a new method for identifying lung nodules in community-based settings...
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