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Metformin Makes Brain Cells Grow
Date: Jul-08-2012The discovery is an important step toward therapies that aim to repair the brain not by introducing new stem cells but rather by spurring those that are already present into action, says the study's lead author Freda Miller of the University of Toronto-affiliated Hospital for Sick Children. The fact that it's a drug that is so widely used and so safe makes the news all that much better. Earlier work by Miller's team highlighted a pathway known as aPKC-CBP for its essential role in telling neural stem cells where and when to differentiate into mature neurons...
Step Closer To Understanding Childhood Degenerative Brain Disease Ataxia-Telangiectasia
Date: Jul-07-2012Researchers at UQ's Australian Institute for Bioengineering and Nanotechnology (AIBN) are a step closer to understanding and combating the degenerative brain disease ataxia-telangiectasia. As part of a collaborative project, Associate Professor Ernst Wolvetang's AIBN research group has reprogrammed, for the first time, skin cells from people with the disease so they can study the effectiveness of potential treatments...
Some Patients With Multiple Sclerosis Experience Fewer Flu-Like Symptoms With Fingolimod
Date: Jul-07-2012The immunosuppressive drug fingolimod (trade name: Gilenya®) is approved for the treatment of highly-active relapsing-remitting multiple sclerosis (RRMS) in adults. In an early benefit assessment pursuant to "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) assessed whether fingolimod offers an added benefit compared with the present standard therapy...
The Origins Of Key Immune Cells
Date: Jul-07-2012Chronic inflammatory conditions are extremely common diseases in humans and in the entire animal kingdom. Both in autoimmune diseases and pathogen-caused diseases, the inflamed areas are rapidly colonized by antibody producing B lymphocytes - which organize themselves in highly structured areas called "lymphoid follicles". The scaffold of such follicles is provided by follicular dendritic cells (FDCs). FDCs have important roles in the development of immune responses, since they trap antigens for protracted periods, thereby training B lymphocytes to recognize the invaders...
Obesity Linked To Acute Kidney Injury After Heart Surgery
Date: Jul-07-2012Obesity increases the risk of acute kidney injury (AKI) following cardiac surgery, according to a Vanderbilt study published in the Journal of the American Society of Nephrology. Considered common after cardiac surgery, AKI represents a fivefold increase in mortality risk within 30 days after the procedure and is associated with longer hospital stays and a range of complications. The study, led by anesthesiologist Frederic T. (Josh) Billings IV, M.D., M.Sc., followed a sample of 455 cardiac surgery patients at Vanderbilt University Hospital and Brigham and Women's Hospital in Boston...
Robotic Legs Accurately Mimic Human Walking Gait
Date: Jul-07-2012A group of US researchers has produced a robotic set of legs which they believe is the first to fully model walking in a biologically accurate manner...
Fertility Drug Usage And Cancer Risk
Date: Jul-07-2012Women using fertility drugs who did not conceive a 10-plus week pregnancy were at a statistically significant reduced risk of breast cancer compared to nonusers; however, women using the drugs who conceived a 10-plus week pregnancy had a statistically significant increased risk of breast cancer compared to unsuccessfully treated women, but a comparable risk to nonusers, according to a study published July 6 in the Journal of The National Cancer Institute...
Research Shows Genetic Factors 'Modestly' Affect Alcoholic Liver Disease Risk
Date: Jul-07-2012Research has suggested that environmental factors have a greater impact on the risk of alcoholic liver disease (ALD) than genetic predisposition. A team of researchers at Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield has published results this month in the European Journal of Gastroenterology and Hepatology showing that patients with ALD are no more likely to have relatives with ALD than are heavy drinkers without evidence of liver disease...
Some People Suffer Allergy-Like Symptoms After Drinking Wine
Date: Jul-07-2012Around seven percent of adults suffer from an intolerance to wine. This is the result of a survey presented by Peter Wigand and co-authors in the current edition of Deutsches Arzteblatt International (Dtsch Arztelb Int 2012; 109 (25): 437-44). The authors evaluated 948 questionnaires that were returned from the 4000 sent out to randomly selected people between the ages of 20 and 69 years. They found that women (8.9%) were more often affected by an intolerance to wine than men (5.2%). The most commonly reported reactions included flushed and itchy skin and a runny nose...
Uxogyn Presents New Data Showing The Ability Of Eeva™ To Non-Invasively Predict Embryo Advancement With Increased Accuracy
Date: Jul-07-2012Auxogyn, Inc., a company focused on revolutionizing the field of reproductive health, has presented data showing the ability of its flagship product, the Early Embryo Viability Assessment (Eeva) Test, to predict embryo advancement with a new level of accuracy. The Eeva™ Test uses intelligent computer vision software to measure key parameters from video images and predicts with high accuracy at the cleavage stage which embryos will likely grow to the blastocyst stage...
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