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Poor Glucose Control Impacts On Cognition
Date: Jun-21-2012A study featured Online First in Archives of Neurology reveals that Diabetes mellitus (DM) and poor glucose control in older, well-functioning adults with no dementia are linked to reduced cognitive function and higher cognitive decline. Background information in the study states that earlier studies indicated a link between DM and a higher risk of cognitive impairment as well as dementia and Alzheimer's. However, this association still creates controversy, as the knowledge about incident DM in late life and cognitive function over time still remains inadequate...
Revlimid (lenalidomide) Extension Of Indication Submission Withdrawn, Europe
Date: Jun-21-2012The European Medicines Agency has been informed by Celgene Europe Limited that it has withdrawn its submission for approval for Revlimid (lenalidomide) - an application for an extension of the therapeutic indication in newly diagnosed multiple myeloma (blood cancer) patients, as well as new pack sizes had been sought. Business analysts say this is a setback for Celgene Europe's best-selling medication, which was expected to grow...
Does Psoriasis Increase Type 2 Diabetes Risk?
Date: Jun-21-2012Two to four percent of adults suffer from psoriasis, a common chronic inflammatory disease, in which the irritated skin becomes red and flaky with silver-white scales. A new UK study, published Online First in JAMA's Archives of Dermatology, has now revealed that psoriasis could be a potential risk factor for developing type 2 diabetes mellitus (T2DM). Rahat S. Azfar, M.D...
Cardiovascular Mortality Rates Higher Among Elderly Who Live Alone
Date: Jun-21-2012It is estimated that one in seven American adults live alone. An international study of stable outpatients who were either at risk of or suffered from arterial vascular disease, such as coronary disease or peripheral vascular disease has now discovered that individuals who live alone have a higher risk of mortality and cardiovascular mortality. The study, published Online First in JAMA's Archives of Internal Medicine reveals that social isolation may be linked to poor health outcomes...
Eating Disorders Affect Older Women Too
Date: Jun-21-2012Eating disorders and aggressive weight loss strategies are commonly seen as something more associated with teenagers and young women and bulimic or anorexic girls are generally believed to be rarely older than in their early twenties. However, this is not so, says a new study published in the International Journal of Eating Disorders. Age, it seems, has little to do with body image, weight and shape. The recent study shows women over fifty wrestling with body issues, with 70% saying they are trying to lose weight, 8% reporting purging (forcing themselves to throw up after eating), and 3...
Bariatric Surgery - Which Diabetes Patients Achieve Complete Remission?
Date: Jun-21-2012According to a new study, 67% of patients with Type 2 diabetes who underwent bariatric surgery achieved complete diabetes remission 1 year after the procedure. However, if patients were not on insulin and did not have reduced pancreatic function, as measured by the glucose disposition index (GDI), this figure increased to over 96%. The study was presented at the 29th Annual Meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS). The researchers examined 139 patients with Type 2 diabetes who underwent a gastric bypass...
Antioxidant Enzyme Reduces Cardiovascular Disease Risk
Date: Jun-21-2012According to a study published by PLoS One, researchers have found an enzyme called glutathione peroxidase (GPx3) can significantly lower the risk of heart disease. Gpx3 is a natural antioxidant that helps the body naturally repair itself and helps protect organisms from oxidant injury. Researchers from the University of Minnesota Medical School, in collaboration with the School of Public Health, discovered that the GPx3 enzyme could potentially be a significant benefit for patients with low levels of good cholesterol (HDL)...
Slowing Aging By Blocking A Protein
Date: Jun-21-2012Researchers at the University of Pittsburgh School of Medicine have successfully slowed down the aging process in mice by blocking a protein that regulates the activity of certain genes. The study is published in the Journal of Clinical Investigation. The teams findings could lead to the development of new drugs that prevent cellular damage from aging, cancer, and diseases caused by abnormal DNA repair activity. Senior author Paul Robbins, Ph.D...
Weight Loss Surgery - Females And Caucasians Respond Best
Date: Jun-21-2012Researchers from Einstein Healthcare Network in Philadelphia have found that white patients and women who undergo gastric bypass surgery lost more weight than African-Americans and males. The study, which followed 1,096 gastric bypass patients, was presented at the 29th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS). Study participants were, on average, 45 years of age, and had an average body mass index (BMI) of 47.6...
McGill Researchers Discover The Cause Of An Inherited Form Of Epilepsy
Date: Jun-21-2012Researchers at McGill University have discovered the cause of an inherited form of epilepsy. The disease, known as double-cortex syndrome, primarily affects females and arises from mutations on a gene located on the X chromosome. Drs. Susanne Bechstedt and Gary Brouhard of the Department of Biology have used a highly advanced microscope to discover how these mutations cause a malformation of the human brain. The results of their study are published in the journal Developmental Cell. When the brain develops in the uterus, new brain cells are born deep within the brain, near the center...
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