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Study Sheds Light On Risk Of Bariatric Procedures Including Increased Alcohol Use Disorders Over Time
Date: Jun-19-2012Adults who had a common bariatric surgery to lose weight had a significantly higher risk of alcohol use disorders (AUD) two years after surgery, according to a study by a National Institutes of Health research consortium. Researchers investigated alcohol consumption and alcohol use disorders symptoms in 1,945 participants from the NIH-funded Longitudinal Assessment of Bariatric Surgery (LABS), a prospective study of patients undergoing weight-loss surgery at one of 10 hospitals across the United States...
BI-1 Suppression Reduced Human Lung Cancer Tumor Growth In Animal Models
Date: Jun-19-2012A multi-institutional research study has uncovered a new mechanism that may lead to unique treatments for lung cancer, one of the leading causes of death worldwide. The study recently published in the journal Genes & Development was a collaboration between Sanford-Burnham Medical Research Institute, Virginia Commonwealth University (VCU) Massey Cancer Center and the VCU Institute of Molecular Medicine, the University of California, San Diego, the University of Minnesota and St. Jude Children's Research Hospital...
Risk Of Death From Stroke Increased By Psychological Distress
Date: Jun-19-2012Psychological distress was associated with a higher risk of death from stroke, according to a study published in CMAJ (Canadian Medical Association Journal). Psychological distress includes factors such as anxiety, depression, sleeping problems and loss of confidence, and is common in approximately 15%-20% of the general population. Although there is evidence linking psychological distress to coronary artery disease, there is a dearth of data linking psychological distress with the risk of death from stroke and other cerebrovascular diseases...
After Brain Injury In Children, Outcomes Difficult To Predict And Highly Variable
Date: Jun-19-2012Outcomes for children with brain injury acquired during childhood are difficult to predict and vary significantly, states an analysis of evidence on the topic published in CMAJ (Canadian Medical Association Journal). "There is no single best approach to describing outcome after acquired brain injury during childhood, and the one chosen must be appropriate to the purpose at hand (e.g., identifying individual, population, global or domain-specific outcomes)," writes Dr...
News From The Annals Of Internal Medicine: June 19, 2012, Online
Date: Jun-19-20121. Hospitalization Often Catastrophic for Alzheimer Patients Hospitalization of patients with Alzheimer disease (AD) often leads to complications such as delirium, loss of independence, institutionalization, and death. Researchers theorized that AD patients who suffer an episode of delirium during hospitalization are at increased risk for adverse outcomes...
Global Fatness Adds Half Billion Extra People
Date: Jun-19-2012Population fatness puts as big a pressure on world resources as numbers, and the global effect of overweight and obese people is like adding half a billion to the 7 billion humans on the planet, scientists revealed this week. Looking at the planet's distribution of human biomass and the effect of obesity, the researchers found that while North America is home to 6% of the world's population, it is responsible for more than a third of global obesity. Around half the food a human being eats is burned up in physical activity...
Cause Of Chronic Sinus Condition Better Understood Following Microbiome Analysis
Date: Jun-19-2012A study of the microbiome of the human nose provides clues to the cause of a chronic sinus condition and potential strategy for a cure. Researchers from the University of California, San Francisco reported their findings at the 2012 General Meeting of the American Society for Microbiology. Chronic rhinosinusitis (CRS) is characterized by inflammation of the nasal and paranasal sinuses lasting over 12 weeks...
New Sequencing Method Finds Gaps That Can Lead To Disease
Date: Jun-19-2012Scientists worldwide are racing to sequence DNA - decipher genetic blueprints - faster and cheaper than ever by passing strands of the genetic material through molecule-sized pores. Now, University of Utah scientists have adapted this "nanopore" method to find DNA damage that can lead to mutations and disease. The chemists report the advance in the week of June 18 online edition of the journal Proceedings of the National Academy of Sciences...
News From The Journal Of Clinical Investigation: June 18, 2012
Date: Jun-19-2012AGING Preventing cellular aging and aging-related degenerative diseases Age-associated degeneration is caused, at least in part, by accumulated cellular damage, including DNA damage, but how these types of damage drive aging remains unclear. Dr. Paul Robbins and colleagues at the University of Pittsburgh sought to address this question using a mouse model of DNA repair deficiency. The Robbins team found that DNA damage drives aging, in part, by activating NF-κB, a transcription factor that responds to cellular damage and stress...
Potential Link Between Intestinal Bacteria And Inflammation
Date: Jun-19-2012Researchers at Baylor College of Medicine and Texas Children's Hospital have identified commensal bacteria in the human intestine that produce a neurotransmitter that may play a role in preventing or treating inflammatory bowel diseases such as Crohn's disease. "We identified, to our knowledge, the first bifidobacterial strain, Bifidobacterium dentium, that is capable of secreting large amounts of gamma-aminobutyric acid (GABA)...
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