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Health Care Workers At Increased Risk Of Accidents Driving Home After Night Shift
Date: Jun-11-2012The drowsiness experienced by medical staff who have been on night duty can make their driving dangerous, French researchers have found. The first study to use simulated driving tests on medical staff returning home after a night shift showed that, under the monotonous driving conditions similar to those experienced on autoroutes (motorways or highways), it was more difficult for them to hold a straight line while driving than it was when they had not been working overnight. They also had greater difficulty in controlling their speed when driving in monotonous conditions. Dr...
Early Menopause Predicts A Milder Form Of Rheumatoid Arthritis
Date: Jun-11-2012A new study presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism, shows that early menopause predicts a milder form of rheumatoid arthritis (RA). New insights on factors influencing RA are good news for sufferers of the chronic inflammatory disease that currently affects over 2 million women in Europe...
Affordable Care Act Enabled 13.7 Million Young Adults To Be On Their Parents' Health Plans In 2011
Date: Jun-11-2012In 2011, 13.7 million young adults ages 19 to 25 stayed on or joined their parents' health plans, including 6.6 million who would likely not have been able to do so before passage of the Affordable Care Act, according to a new Commonwealth Fund report. However, not all young adults have parents with health plans they can join, and many still experience gaps in coverage and face medical bill problems and medical debt...
Why Concussions Affect People Differently: Novel Brain Imaging Technique
Date: Jun-11-2012Patients vary widely in their response to concussion, but scientists haven't understood why. Now, using a new technique for analyzing data from brain imaging studies, researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that concussion victims have unique spatial patterns of brain abnormalities that change over time...
76 Percent Of Rheumatoid Arthritis Patients On Oral JAK1/JAK2 Inhibitor Plus DMARDS Achieve ACR20 Response At Week 12
Date: Jun-11-2012Data from a Phase IIb study presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism, show that 76% of patients with active rheumatoid arthritis (RA) receiving either 4mg or 8mg of baricitinib, an oral JAK1/JAK2 inhibitor, plus stable methotrexate (MTX) achieved ACR20* response compared with 41% of placebo-treated patients (p less than or equal to 0.001) at 12 weeks...
Predicting Risk Of Serious Infection In Rheumatoid Arthritis Patients Using Rabbit Risk Score
Date: Jun-11-2012Results of a study presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism, suggest that the newly developed RABBIT Risk Score, which calculates the risk of serious infections in patients with rheumatoid arthritis (RA) who are treated with anti-tumour necrosis factor drugs (anti-TNFs) or conventional disease modifying anti-rheumatic drugs (DMARDs) is a valid and effective tool for rheumatologists to predict risk of serious infection...
Researchers Discover New Route To Heart Failure, And Drugs To Match
Date: Jun-11-2012A new study in the journal Circulation packs a powerful one-two punch in the fight against heart failure. The leading blow: Identification of a unique alliance of proteins that plays a major role in the development of the disease. The second but equally powerful hit: Drugs that interfere with this axis already exist. Though still in its infancy, the combination is just the type of research the scientific community is looking for in its efforts to speed up the development of the next generation of treatments for the nation's biggest killers, of which heart disease is the long-reigning champ...
Discovery Provides Evidence Of New Therapeutic Target That Could Delay Axon Decay
Date: Jun-10-2012Degeneration of the axon and synapse, the slender projection through which neurons transmit electrical impulses to neighboring cells, is a hallmark of some of the most crippling neurodegenerative and brain diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease and peripheral neuropathy. Scientists have worked for decades to understand axonal degeneration and its relation to these diseases. Now, researchers at the University of Massachusetts Medical School are the first to describe a gene - dSarm/Sarm1 - responsible for actively promoting axon destruction after injury...
Researchers Make Important Breakthrough In Immunology
Date: Jun-10-2012A team of researchers at the IRCM led by Dr. Andre Veillette made an important breakthrough in the field of immunology, which was published online by the scientific journal Immunity. The scientists explained a poorly understood molecular mechanism associated with a human immune disorder known as XLP disease or Duncan's syndrome. "We studied the SAP molecule, which plays a critical role in multiple different types of immune cells," says Dr. Veillette, Director of the Molecular Oncology research unit at the IRCM...
Innovative Technique Lays Groundwork For Novel Stem Cell Therapies
Date: Jun-10-2012Scientists at the Gladstone Institutes have for the first time transformed skin cells - with a single genetic factor - into cells that develop on their own into an interconnected, functional network of brain cells. The research offers new hope in the fight against many neurological conditions because scientists expect that such a transformation - or reprogramming - of cells may lead to better models for testing drugs for devastating neurodegenerative conditions such as Alzheimer's disease. This research comes at a time of renewed focus on Alzheimer's disease, which currently afflicts 5...
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