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Exercise Affects The Brain

Date: May-23-2012
It is a well-known fact that exercise is good for the body. It clears the mind, improving blood circulation and supplies the brain with more oxygen. According to David Bucci, an associate professor at Dartmouth's Department of Psychological and Brain Sciences, exercise also involves other factors.  He says: "In the last several years there have been data suggesting that neurobiological changes are happening - [there are] very brain-specific mechanisms at work here." Bucci and his team discovered that exercise has different effects on memory and on the brain depending on the person's age, i.e....

Fake, Poor Quality Malaria Drugs Threaten Progress

Date: May-23-2012
Up to 42% of anti-malaria drugs available across Southeast Asia and sub-Saharan Africa are poor quality or fake, resulting in drug resistance and inadequate treatment that threatens vulnerable populations and to undermine the huge progress made in recent years, according to a new study published online in The Lancet Infectious Diseases this week. The study was funded by the Fogarty International Center at the US National Institutes of Health in Bethesda, Maryland, where co-author Dr Joel Breman is Senior Scientist Emeritus. He told the press: "Poor quality antimalarial drugs are very likely to...

New Heart Muscle Cells Grow From Patients' Skin

Date: May-23-2012
In a world first, scientists have grown new, healthy heart muscle cells using skin cells from heart failure patients. Writing about their work in a paper published online this week in the European Heart Journal, the Israel-based team explain how the new heart muscle cells are capable of integrating with exisiting heart tissue, opening up the prospect of repairing heart damage in heart failure patients using their own stem cells. However, the researchers caution there are still many hurdles to overcome before such a method is available for patients, and estimate it may take five to ten years...

Preventing Childhood Obesity: A Systems Approach

Date: May-23-2012
Currently more than 10% of preschoolers in the U.S. are obese and effective strategies that target pregnancy, infancy, and toddlers are urgently needed to stop the progression of the childhood obesity epidemic, as proposed in an article in Childhood Obesity, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free online ahead of print on the Childhood Obesity website.* Evidence increasingly suggests that the risk for childhood obesity begins before and during pregnancy via maternal obesity and excessive gestational weight gain. It is likely that obese...

Scientists Aiming To Activate Tumor Suppressor Gene And Inhibit Cancer

Date: May-23-2012
A team of scientists has developed a promising new strategy for "reactivating" genes that cause cancer tumors to shrink and die. The researchers hope that their discovery will aid in the development of an innovative anti-cancer drug that effectively targets unhealthy, cancerous tissue without damaging healthy, non-cancerous tissue and vital organs. The research will be published in the Journal of Biological Chemistry. The team, led by Yanming Wang, a Penn State University associate professor of biochemistry and molecular biology, and Gong Chen, a Penn State assistant professor of chemistry,...

Patients' Blood Pressure Decreases With Behavioral Support From Peers, Staff

Date: May-23-2012
Behavioral Support From Peers, Staff Main Category: Hypertension Also Included In: Psychology / Psychiatry Article Date: 23 May 2012 - 1:00 PDT  email to a friend   printer friendly   opinions    rate article  Current ratings for: 'Patients' Blood Pressure Decreases With Behavioral Support From Peers, Staff' Patient / Public: Healthcare Prof: 2 (1 votes) Behavioral support from peers and primary care office staff can help patients improve their blood pressure control by as much as starting a new drug, a new study found. Barbara J. Turner, M.D., M.S.Ed., M.A., M.A.C.P., of UT...

News From The Journals Of The American Society For Microbiology

Date: May-23-2012
Genes Culled From Desert Soils Suggest Potential Medical Resource Despite their ecologic similarity, soils from three geographically distinct areas of the American southwest harbor vastly different collections of small, biosynthetic genes, a finding that suggests the existence of a far greater diversity of potentially useful products than was previously supposed. The research is published in the May issue of Applied and Environmental Microbiology. Natural compounds have been the sources of the majority of new drugs approved by the US Food and Drug Administration, and bacteria have been the...

For Pulmonary Hypertension, Inhibition Of PBEF Is A Possible Therapeutic Target

Date: May-23-2012
Inhibition of pre-B Cell Colony-Enhancing Factor (PBEF) could be a potential therapeutic target for pulmonary hypertension (PH), according to a preclinical study in an animal model of PH. "PBEF expression appears to be significantly increased in PH. Accordingly, we examined whether inhibiting PBEF could prevent and reverse PH in rats," said Roberto Machado, MD, associate professor of medicine at the University of Illinois at Chicago. "We found that PBEF not only prevented the development of PH, but was able to reverse established PH, suggesting its potential use as a therapy for PH in humans."...

Nanotechnology In Brain Treatment Research

Date: May-23-2012
Researchers at Purdue University are working with the U.S. Army and neurosurgeons at the Walter Reed National Military Medical Center to create a new type of "bioactive" coating for stents used to treat brain aneurisms including those caused by head trauma from bomb blasts. "Stents coated with a bioactive coating might be inserted at the site of an aneurism to help heal the inside lining of the blood vessel," said Jean Paul Allain, an associate professor of nuclear engineering. "Aneurisms are saclike bulges in blood vessels caused by weakening of artery walls. We're talking about using a...

Severe Asthma With Fungal Sensitization May Be Cause Of Children Failing Asthma Therapy

Date: May-23-2012
New research presented at the ATS 2012 International Conference in San Francisco suggests that a significant proportion of children with asthma failing Step 4 or greater therapy may have severe asthma with fungal sensitization (SAFS). "SAFS is a newly described sub-phenotype of asthma, and its prevalence and clinical characteristics in children are unknown," said Alfin Vicencio, MD, chief of pediatric pulmonology and cystic fibrosis at the Cohen Children's Medical Center in Great Neck, NY, and David Goldman, associate professor of pediatric infectious diseases at the Children's Hospital at...