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Inflammation Related To GERD May Contribute To Esophageal Cancer Risk
Date: May-13-2012Inflammation might be an important factor in the progression from reflux to esophageal cancer, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association. "Our research shows that damage to the esophageal lining that can be seen with endoscopy is important in the progression from normal cells to cancer, and Barrett's esophagus is likely to be an intermediate step," said Rune Erichsen, MD, of Aarhus University Hospital and lead author of this study. In the past three decades, the incidence of esophageal cancer has...
Gene Discovered That Causes Joubert Syndrome
Date: May-13-2012C5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. This is what a study in The American Journal of Human Genetics reveals. The study was conducted by researchers from the Sainte-Justine University Hospital Research Center and the Centre of Excellence in Neuromics of Universite de Montréal (CENUM). Joubert Syndrome is a condition that affects brain development and manifests itself through delayed psychomotor...
Blood Pressure Control Improved With Home Telemonitoring By Pharmacists
Date: May-13-2012Patients receiving telemonitoring along with high blood pressure management support from a pharmacist were more likely to lower their blood pressure than those not receiving extra support, according to research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2012. "Patients with high blood pressure visit physicians an average of four times each year, yet blood pressure is controlled in only about half of U.S. patients," said Karen Margolis, M.D., M.P.H., the study's lead author and director of clinical research of HealthPartners Research...
Rituximab Ineffective For Children With Idiopathic Nephrotic Syndrome
Date: May-12-2012The drug rituximab, an antibody that targets the immune system and is often used to treat immune disorders such as lymphoma and arthritis, has recently emerged as a potential treatment for a childhood kidney disorder known as idiopathic nephrotic syndrome (INS). While the cause of INS is not fully known, it is believed to be an immune disorder. Unfortunately, rituximab does not appear to benefit children who have INS that is resistant to standard treatments, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN). INS has an...
MiR-TRAP Allows Scientists To Better Understand The Roles MicroRNAs Play In Human Development And Disease
Date: May-12-2012Human cells are thought to produce thousands of different microRNAs (miRNAs) - small pieces of genetic material that help determine which genes are turned on or off at a given time. miRNAs are an important part of normal cellular function, but they can also contribute to human disease - some are elevated in certain tumors, for example, where they promote cell survival. But to better understand how miRNAs influence health and disease, researchers first need to know which miRNAs are acting upon which genes - a big challenge considering their sheer number and the fact that each single miRNA can...
Research With Infant Twins Shows That Environmental Conditions Determine Testosterone Levels
Date: May-12-2012By comparing the testosterone levels of five-month old pairs of twins, both identical and non-identical, University of Montreal researchers were able to establish that testosterone levels in infancy are not inherited genetically but rather determined by environmental factors. "Testosterone is a key hormone for the development of male reproductive organs, and it is also associated with behavioural traits, such as sexual behaviour and aggression," said lead author Dr. Richard E. Tremblay of the university's Research Unit on Children's Psychosocial Maladjustment. "Our study is the largest to be...
Faster Treatment For Heart Attack Patients Taken Directly To PCI Hospitals
Date: May-12-2012Heart Attack Patients Taken Directly To PCI Hospitals Main Category: Cardiovascular / Cardiology Also Included In: Public Health Article Date: 12 May 2012 - 0:00 PDT email to a friend printer friendly opinions rate article Current ratings for: 'Faster Treatment For Heart Attack Patients Taken Directly To PCI Hospitals' Patient / Public: Healthcare Prof: Heart attack patients in North Carolina who were rushed directly to hospitals equipped to do percutaneous coronary intervention (PCI) received treatment significantly faster than patients first taken to hospitals...
Genes And Vascular Risk Modify Effects Of Aging On Brain And Cognition
Date: May-12-2012Efforts to understand how the aging process affects the brain and cognition have expanded beyond simply comparing younger and older adults. "Everybody ages differently. By looking at genetic variations and individual differences in markers of vascular health, we begin to understand that preventable factors may affect our chances for successful aging," said Wayne State University psychology doctoral student Andrew Bender, lead author of a study supported by the National Institute on Aging of the National Institutes of Health and now in press in the journal Neuropsychologia. The report,...
Kidney Donation Hindered By Obesity
Date: May-12-2012Researchers at the Hofstra North Shore-LIJ School of Medicine and Feinstein Institute for Medical Research conducted a retrospective analysis which found that morbid obesity impedes kidney donation. In fact, in the analysis of 104 potential living kidney donors, 23 (22 percent) donors were classified as morbidly obese, only three (13 percent) of whom were able to successfully lose weight and donate their kidney. This data was presented at the National Kidney Foundation (NKF) 2012 Spring Clinical Meetings, being held from May 9-13 in Washington, DC. Morbidly obese patients are generally...
Predicting The Risk Of Sudden Cardiac Arrest Using Novel Imaging Could Better Identify Patients Who Would Benefit From ICDs
Date: May-12-2012New research from the University at Buffalo suggests that cardiologists may have a new way to identify patients who are at the highest risk of sudden cardiac arrest, and the most likely to benefit from receiving an implantable cardiac defibrillator (ICD). ICDs are used to prevent sudden cardiac arrest in patients with advanced heart disease, but many patients' devices are never triggered. New research suggests that imaging the loss of nerve function in the heart may identify those patients at greatest risk of developing a life-threatening arrhythmia. That finding was reported as a...
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