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Discovery Of First Gene Linked To Missing Spleen In Newborns
Date: May-07-2012Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children at risk of dying from infections they cannot defend themselves against. The gene, Nkx2.5, was shown to regulate genesis of the spleen during early development in mice. The study, published online in Developmental Cell, raises the hope that a simple genetic screening test for Nkx2.5 mutations can be developed that will alert parents that their developing child may be missing the organ, which...
Presence Of Fetal Cells In Women Lowers Risk Of Breast Cancer But Raises Risk Of Colon Cancer
Date: May-07-2012For the first time, scientists have found what could be a causative link between the concentration of circulating Y-chromosome fetal cells in women who gave birth to children of either sex and their risk of later developing breast cancer and colon cancer. The findings show that the presence of fetal cells is a double-edged sword: Women with the lowest concentration of fetal cells were 70 percent less likely to have breast cancer, while women with the highest concentration of fetal cells had a four-fold increased risk for colon cancer when compared with healthy controls. The how and why of this...
SPECT/CT Improves Staging And Risk Stratification Of Thyroid Cancer
Date: May-07-2012The use of single positron emission computed tomography (SPECT)/computed tomography (CT) has been reported to change clinical management in a significant number of thyroid cancer patients according to research presented in the May issue of /i>The Journal of Nuclear Medicine. Information obtained from these scans not only helps determine the need for radioiodine therapy or alterative options, but also impacts the long-term follow-up strategy. "In this article I aimed to highlight the role of radioiodine imaging in risk stratification of patients with thyroid cancer and to assess the...
Possible Protective Blood Factors Against Type 2 Diabetes Identified By Study
Date: May-07-2012Researchers at Albert Einstein College of Medicine of Yeshiva University in collaboration with Nurses' Health Study investigators have shown that levels of certain related proteins found in blood are associated with a greatly reduced risk for developing type 2 diabetes up to a decade or more later. The findings, published in the online edition of Diabetes, could open a new front in the war against diabetes. These proteins are part of what is called the IGF axis. This axis was named for insulin-like growth factor-1, (IGF-1), so called because it has biological effects similar to those of...
Environmental Epigenetics And Ovarian Disease
Date: May-07-2012Washington State University researchers have found that ovarian disease can result from exposures to a wide range of environmental chemicals and be inherited by future generations. WSU reproductive biologist Michael Skinner and his laboratory colleagues looked at how a fungicide, pesticide, plastic, dioxin and hydrocarbon mixtures affected a gestating rat's progeny for multiple generations. They saw subsequent generations inherit ovarian disease by "epigenetic transgenerational inheritance." Epigenetics regulates how genes are turned on and off in tissues and cells. Three generations were...
Prostate Cancer Stem Cells Identified Among Low-PSA Cells
Date: May-07-2012Prostate Cancer Psychology / Psychiatry Public Health Radiology / Nuclear Medicine Regulatory Affairs Rehabilitation Respiratory Restless Legs Syndrome s - z Schizophrenia Seniors / Aging Sexual Health / STDs Sleep / Sleep Disorders Smoking / Quit Smoking Sports Medicine / Fitness Statins Stem Cell Research Stroke Swine Flu Transplants / Organ Donations Tropical Diseases Tuberculosis Urology / Nephrology Vascular Veterans / Ex-Servicemen Veterinary Viruses / Bacteria Water - Air Quality / Agriculture ...
Daily Omega 3 Fatty Acids In Fish May Ward Off Heart Disease
Date: May-07-2012Most people, whether healthy or having cardiovascular disease (CVD), would benefit from regular consumption of oily fish, concluded speakers at the EuroPRevent 2012 meeting. While eating whole fish undoubtedly offers the optimum approach for increasing omega-3 intakes in both primary and secondary prevention, delegates heard, supplements have a major role to play in increasing omega-3 intakes for people who do not like fish. The EuroPRevent 2012 meeting,in Dublin, Ireland, was organised by the European Association for Cardiovascular Prevention and Rehabilitation (EACPR), a registered branch of...
Moderate, Regular Jogging Relates To Dramatic Increase In Life Expectancy
Date: May-07-2012Undertaking regular jogging increases the life expectancy of men by 6.2 years and women by 5.6 years, reveals the latest data from the Copenhagen City Heart study presented at the EuroPRevent2012 meeting. Reviewing the evidence of whether jogging is healthy or hazardous, Peter Schnohr told delegates that the study's most recent analysis (unpublished) shows that between one and two-and-a-half hours of jogging per week at a "slow or average" pace delivers optimum benefits for longevity. The EuroPRevent2012 meeting, held in Dublin, Ireland, was organised by the European Association for...
Preventing The Passing Of Mitochondrial Mutations From Mother To Child
Date: May-07-2012Research conducted at the Oregon National Primate Research Center at Oregon Health & Science University helps answer some long-standing questions about how certain disease-causing gene mutations are inherited. The research specifically focused on gene mutations in cell mitochondria that can cause several diseases, including forms of cancer, diabetes, infertility and neurodegenerative diseases. With this new information, we now better understand how and when these mutations are passed to children to improve diagnosis and prevention. The research will be published online in the journal Cell...
Extensive Study Questions Previous Study's Analytic Methods Regarding Cardiovascular Safety Concerns Over Smoking-Cessation Drug
Date: May-07-2012A popular smoking cessation medication has been under a cloud of suspicion ever since the Canadian Medical Association Journal (CMAJ) published a study in July 2011 reporting "risk of serious adverse cardiovascular events associated with varenicline." Varenicline, also known as Chantix, blocks the pleasant effects of nicotine on the smoker's brain and lessens nicotine withdrawal symptoms. UCSF researchers, however, question the way the previous study was conducted, and their new analysis in BMJ reaches a very different conclusion. "We found no clinically or statistically significant increase...
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