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Weill Cornell scientists find gene implicated in progression and relapse of deadly breast cancer

Date: Mar-26-2014
Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in Nature, suggests that targeting the gene may be a new approach to treating the disease.About 42,000 new cases of triple negative breast cancer (TNBC) are diagnosed in the United States each year, about 20 percent of all breast cancer diagnoses.

Immunotherapy data heralds new era of lung cancer treatment

Date: Mar-26-2014
A new era of lung cancer therapy is close to dawning, using drugs that can prevent tumour cells from evading the immune system, experts have said at the 4th European Lung Cancer Congress.For decades, scientists and doctors thought immunotherapy - treatments that harness the immune system to fight a disease - was of marginal benefit in lung cancer, says Jean-Charles Soria, Institute Gustave Roussy in Paris, France.However a new class of drugs known as "immunocheckpoint regulators" have shown huge potential, Soria says. New data on several of these drugs are presented at the conference.

Researchers take mathematical route to fighting viruses

Date: Mar-26-2014
Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.The researchers have constructed a mathematical model that provides important new insights about the molecular mechanisms behind virus assembly which helps to explain the efficiency of their operation.

Researchers take mathematical route to fighting viruses

Date: Mar-26-2014
Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.The researchers have constructed a mathematical model that provides important new insights about the molecular mechanisms behind virus assembly which helps to explain the efficiency of their operation.

Elsevier's Maturitas publishes position statement on the management of postmenopausal women with vertebral osteoporotic fracture

Date: Mar-26-2014
Elsevier, a world-leading provider of scientific, technical and medical information products and services, has announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) in the journal Maturitas on the topic of the management of postmenopausal women with vertebral osteoporotic fracture.Vertebral osteoporotic fracture is an underestimated condition as only about a third of people with the disease seek medical attention. While it may cause acute back pain, the presentation may be insidious with gradual loss of height.

Elsevier's Maturitas publishes position statement on the management of postmenopausal women with vertebral osteoporotic fracture

Date: Mar-26-2014
Elsevier, a world-leading provider of scientific, technical and medical information products and services, has announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) in the journal Maturitas on the topic of the management of postmenopausal women with vertebral osteoporotic fracture.Vertebral osteoporotic fracture is an underestimated condition as only about a third of people with the disease seek medical attention. While it may cause acute back pain, the presentation may be insidious with gradual loss of height.

Certain genetic variants may put bladder cancer patients at increased risk of cancer recurrence

Date: Mar-26-2014
In the Western world, bladder cancer is the fourth most common cancer in men and the eighth most common in women, with many patients experiencing recurrence after treatment. A new study published in BJU International indicates that inheriting certain DNA sequences can affect a patient's prognosis. The findings may help physicians identify sub-groups of bladder cancer patients who should receive intensive treatment and monitoring.Nearly half of patients diagnosed with bladder cancer experience tumor recurrences, but it is difficult to predict which patients are at risk.

Certain genetic variants may put bladder cancer patients at increased risk of cancer recurrence

Date: Mar-26-2014
In the Western world, bladder cancer is the fourth most common cancer in men and the eighth most common in women, with many patients experiencing recurrence after treatment. A new study published in BJU International indicates that inheriting certain DNA sequences can affect a patient's prognosis. The findings may help physicians identify sub-groups of bladder cancer patients who should receive intensive treatment and monitoring.Nearly half of patients diagnosed with bladder cancer experience tumor recurrences, but it is difficult to predict which patients are at risk.

Certain genetic variants may put bladder cancer patients at increased risk of cancer recurrence

Date: Mar-26-2014
In the Western world, bladder cancer is the fourth most common cancer in men and the eighth most common in women, with many patients experiencing recurrence after treatment. A new study published in BJU International indicates that inheriting certain DNA sequences can affect a patient's prognosis. The findings may help physicians identify sub-groups of bladder cancer patients who should receive intensive treatment and monitoring.Nearly half of patients diagnosed with bladder cancer experience tumor recurrences, but it is difficult to predict which patients are at risk.

Blood glucose measure appears to provide little benefit in predicting risk of cardiovascular disease

Date: Mar-26-2014
In a study that included nearly 300,000 adults without a known history of diabetes or cardiovascular disease (CVD), adding information about glycated hemoglobin (HbA 1c ), a measure of longer-term blood sugar control, to conventional CVD risk factors like smoking and cholesterol was associated with little improvement in the prediction of CVD risk, according to a study in JAMA.